The invention mainly relates to a
monensin sodium premix and a preparation method thereof, and belongs to the technical field of
veterinary drugs. The preparation method comprises the following steps: carrying out
enzyme wall breaking inactivation,
ionic solution system pore forming and
sodium loading on a
monensin fermentation solution to obtain a
monensin sodium treatment solution, and carrying out auxiliary material dispersion,
solid-liquid separation and preparation on the treatment solution to obtain the
monensin sodium premixing agent. According to the preparation method disclosed by the invention, Na < + > loading of monensin can be promoted by adopting
enzyme wall breaking and
ionic solution system pore forming, formation of
monensin sodium is facilitated, loss of Na < + > in a
solid-liquid
separation process is avoided, the sodium loading amount is remarkably increased, and improvement of the
pesticide effect is facilitated; meanwhile, the process preparation is simple, the heating and
organic solvent extraction processes are avoided, the filtrate can form recyclable
reclaimed water after purification treatment, and the method is more energy-saving, environment-friendly and safe.