5 results about "Topical microbicides" patented technology

A method of sterilizing biological tissue such as soft mammalian tissue that can be used to make bioprosthetic devices is disclosed. The method comprises contacting biological tissue with a bioburden reduction mixture, contacting biological tissue with a tissue drying mixture, and thereafter sterilizing the dry tissue with supercritical carbon dioxide. Prior to sterilizing the biological tissue with supercritical carbon dioxide, the biological tissue is placed under vacuum and, in some embodiments, is treated with a vaporized microbicide. Bioprosthetic devices made using the methods disclosed herein include bioprosthetic heart valves, biological tissue derived vascular grafts or vessels, and surgical tissue patches.

Provided is a microbicide-containing aqueous composition having a superior effect of stabilizing 5-chloro-2-methyl-4-isothiazolin-3-one. This microbicide composition includes: (A) 5-chloro-2-methyl-4-isothiazolin-3-one; (B) 2,2,6,6-tetramethylpiperidin-1-oxyl; and (C) at least one solvent selected from the group consisting of water and a hydrophilic organic solvent.

A plant disease control composition includes Tebufloquin and a microbicide other than Tebufloquin as active components. The microbicide includes at least one selected from the group consisting of Pyraclostrobin, Picoxystrobin, Fluoxastrobin, Mandestrobin, Trifloxystrobin, Azaconazol, Bitertanol, Bromuconazole, Ciproconazole, Diphenoconazole, Diniconazole, Epoxiconazole, Etaconazole, Fenbuconazole, Fluquinconazole, Flusilazole, Flutriafol, Hexaconazole, Imibenconazole, Ipconazole, Mefentrifluconazole, Metconazole, Myclobutanil, Penconazole, Propiconazole, Prothioconazole, Simeconazole, Mefentrifluconazole, Tebuconazole, Tetraconazole, Triadimefon, Triadimenol, Triticonazole, Penflufen, Inpyrfluxam, Fluindapyr, Pyraziflumid, Penthiopyrad, Fluopyram, Pyridachlometyl, Pyroquilon, and Ipflufenoquin.

Compound of formula I wherein R1 is C1-C4alkyl or C1-C4haloalkyl; R2 is hydrogen, fluoro or chloro; R3 is hydrogen or C1-C4alkyl; R4 and R5, independently from each other, are hydrogen or C1-C4alkyl; X is oxygen, sulfur or absent; R6 is C1-C4alkyl or Crathaloalkyl if X is oxygen or sulfur, or is hydrogen if X is absent; R7 and R8 independently from each other, are hydrogen, halogen or=-R9; with the proviso that at least one of R7 and R8 is different from hydrogen; m is 1, 2, 3 or 4; R9 is hydrogen, C1-C6alkyl, C1-C6haloalkyl or C1-C4alkoxyalkyl; are suitable for use as microbiocides.

A catheter system may include a catheter adapter, which may include a distal end and a proximal end. The catheter system may include a catheter extending from the distal end of the catheter adapter. The catheter may include an outer surface having an active area and a passive area proximate the active area. In some embodiments, a plurality of active areas and a plurality of passive areas alternate along a length of the catheter. The active area includes one or more microbiocidal agents. The passive area includes a nitric oxide-generating compound and a glycocalyx polysaccharide matrix to simulate vascular endothelial surface. In further detail, the passive area may be superhydrophilic.