The invention discloses a urea mixing device. A partition is arranged between a front housing and a rear housing, a breaking plate is fixed to the partition, a front baffle is arranged on the front end part of the partition, an opening is formed in a part corresponding to the partition, of the front baffle, a flow guide plate and a hole plate are arranged on the opening, and an intake port is formed between the flow guide plate and an inner wall surface corresponding to the front housing; a blade opened inwards and towards an injection cavity is formed in the flow guide plate; a plurality of first through holes are formed in the hole plate; grating openings are formed in a wall surface facing the breaking plate, of the partition; and the rear housing is provided with a waist-reducing part.According to the urea mixing device, the plurality of grating openings are formed in the part facing the breaking plate, of the partition, and play a role of secondary breaking on urea drops, and more thorough atomization and volatilization for the urea drops are ensured, so that adequate mixing for mixed gas flow is much benefited, and higher mixing uniformity is achieved. The rear housing is provided with the waist-reducing part, and the flowing speed of the mixed gas flow while passing through the waist-reducing part, is increased, so that a better mixing effect and higher mixing uniformity are achieved.