The present invention relates to an osmosis water purifier with real-time monitoring. The osmosis water purifier comprises a water pump, a filtration unit, a RO reverse osmosis membrane treatment unit, and a water storage barrel connected to the purified water outlet pipe of the RO reverse osmosis membrane treatment unit, wherein the filtration unit and the RO reverse osmosis membrane treatment unit are sequentially connected to a water inlet pipe, the water inlet pipe position of the RO reverse osmosis membrane treatment unit is provided with an electromagnetic valve, the filtration unit sequentially comprises a PP filtration core, a granular active carbon filtration core and a compressed carbon filtration core, the water outlet ends of every stage of the filtration cores of the filtration unit are respectively provided with a water flow rate monitoring device, the water outlet end of the RO reverse osmosis membrane treatment unit is provided with a TDS detection device, and a water flow rate detection device and the TDS detection device are connected to a display device. According to the present invention, the osmosis water purifier has beneficial effects of timely filtration assembly monitoring, RO reverse osmosis membrane service life prolonging, energy consumption reducing, and wastewater output reducing.