Compound electrolytic fructose injection

A compound electrolyte and injection technology, applied in the field of medicine, can solve problems such as increasing water and electrolyte disorders, and achieve the effects of reducing blood sugar fluctuations, reducing the number of drug additions, and reducing the number of liquid replacements

Active Publication Date: 2007-08-29
上海致真生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, when the urine sugar increases, the osmotic diuretic effect of glucose will cause important ions such as sodium and potassium in the patient's body and water to be lost with the urine, thereby increasing the possibility of water and electrolyte disorders.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1. preparation compound electrolyte fructose injection

[0020] No fruit sugar 1710g, NaCl 515.7g, CaCl 2 2H 2 O 29.4g, MgCl 2 ·6H 2 Add 17.1g of O, 29.8g of KCl, 291.4g of sodium lactate, water for injection to 100L, mix well, adjust the pH to 4.5 with hydrochloric acid, pack into 100 bags, 1000ml / bag, seal and sterilize at high temperature.

[0021] Animal experiments have proved that after infusion of the injection of the present invention, the level of electrolytes and pH in the blood of grass dogs do not change significantly before and after infusion, and the blood sugar level is also significantly lower than that of the control group.

[0022] During the clinical trial of the present invention, the determination of K in the blood of kidney transplantation patients at different time points after operation + 、Na + , Cl - , Ca 2+ , carbon dioxide binding capacity, blood sugar and urine sugar and other values, the results are shown in Table 2 and Tab...

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PUM

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Abstract

Disclosed is a compound electrolytic fructose injection for fluid replacement treatment in diuresis period after kidney transplantation surgery, wherein levulose is used for substituting glucose, for making compound injection with correct concentration range, The volume of the transfusion bottle and the transfusion bag is increased, thus simplifying transfusion operational program, reducing working capacity of fluid replacement treatment, and overcoming the possible pollution and error caused by frequent replacement of transfusion bottle or bag.

Description

technical field [0001] The invention relates to the technical field of medicine, and relates to a compound electrolyte fructose injection used for postoperative fluid infusion, and is especially suitable for fluid infusion treatment in polyuria period after kidney transplantation. Background technique [0002] Clinically, patients after surgery often cannot eat a large amount of food immediately, and need to replenish water, electrolytes and calories from the veins. Electrolyte solutions are also needed during hemorrhagic shock from surgery or trauma. Most of the commonly used rehydration schemes are to supplement electrolytes with balance fluid, and glucose solution to supplement the heat and water needed by the human body. However, because the body is in a state of stress after surgery or trauma, the ability to utilize glucose is reduced, and a large amount of glucose quickly input can not be fully utilized by the body, but also can lead to a significant increase in blood...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7004A61K9/08A61P3/12
Inventor 朱有华张晓萍胡琛李朴清张纯
Owner 上海致真生物科技有限公司
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