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Granule for treating hyperosteogeny and preparation method thereof

A technology for bone hyperplasia and granules, which is applied in the field of preparations for the treatment of osteoporosis and hyperostosis, can solve the problems of inconvenience for patients to take, the amount of added oyster is not clear, the amount of oyster is large, etc., and can improve the biomechanics of tibia and femur Low cost, increased femoral weight and length

Active Publication Date: 2007-08-08
湖北欣泽霏药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the vinegar extraction process, the extraction frequency and time are stipulated, but the amount of addition is not specified; after drying, it is directly crushed into fine powder, which is easy to absorb moisture, has poor taste, and is not convenient for patients to take; 3000g oysters are finally made into 1000g powder, oyster High consumption and high cost

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] This granule is mainly composed of oysters, which can promote bone formation, maintain nerve conduction, muscle contraction, normal capillary osmotic pressure, and maintain blood acid-base balance. It is used for the treatment of osteoporosis, hyperosteogeny, bone pain, muscle spasm and rickets in children, adults or the elderly caused by calcium deficiency. The present invention changes Shengu powder into granules, and when changing the dosage form, on the premise of ensuring that there is no qualitative change before molding, the relevant parameters of the preparation process are optimized, and the quality standard is improved, so as to better control the quality of the preparation.

[0015] 1. Vinegar extraction research: extract with multiple edible vinegar respectively, other steps remain unchanged according to the original process, concentrate to a thick paste with a relative density of 1.35 (80°C), vacuum dry at 80°C, and the dry paste yield is Investigate the in...

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Abstract

The invention relates to a method for preparing the particles which can treat osteoporosis and hyperosteogeny. The inventive particle is formed by oyster powder and findings, amidon pulp or alchol. And the preparation comprises that breaking oyster into rough powder, to be immerged and extracted by vinegar for three times; combining the extractives, filtering, depressurizing and concentrating the filter liquor into dense paste to be vacuum dried and broken; adding finding into the paste powder, mixing uniformly, adding amidon pulp or alcohol to prepare soft material and particles, to obtain the while particle agent. The invention can prepare particle agents, added with findings and reduced with oyster consumption, with low cost and better taste. The animal test has proved the osteoporosis resistance of said particle agent.

Description

technical field [0001] The invention relates to a preparation capable of treating osteoporosis and hyperosteogeny and a preparation method thereof. Background technique [0002] Osteoporosis, hyperosteogeny, and rickets in children are common senile diseases and frequently-occurring diseases in children, which seriously endanger the health of the crowd. Shengusan is currently used in the treatment of osteoporosis, hyperosteogeny, and rickets in children. Kidney bone powder was originally recorded in the local standard and upgraded to the national standard orthopedics volume, standard number WS-10453(ZD-0453)-2002. It is to extract 3000g oysters with edible vinegar three times (80°C, 24 hours, 12 hours, 12 hours), combine the extracts, filter, concentrate the filtrate under reduced pressure to a thick paste, dry it in vacuum at 80°C, and pulverize it. Get powder. In the vinegar extraction process, the number and time of extraction are stipulated, but the amount of addition...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61K9/16A61P19/10A61K35/618
Inventor 鲁至诚
Owner 湖北欣泽霏药业有限公司