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Use of extract of bracken flavone as medicament for lead expelling and lead poisioning alleviation

A technology of bracken flavonoids and extracts, applied in the direction of medical raw materials, drug combinations, and anti-toxins derived from ferns/filamentous plants, can solve problems such as side effects and malnutrition, and achieve small side effects, small toxic side effects, The effect of convenience

Inactive Publication Date: 2007-08-08
WEST ANHUI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While these drugs excrete lead, they also excrete essential trace elements in the body, resulting in malnutrition and obvious side effects.

Method used

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  • Use of extract of bracken flavone as medicament for lead expelling and lead poisioning alleviation

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Experimental program
Comparison scheme
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Embodiment Construction

[0026] In order to better understand the essence of the present invention, the new application of the bracken flavone extract in the field of pharmacy will be described below through specific experimental results and data.

[0027] (1) The experimental basis of bracken flavonoid extract in the aspect of lead discharge:

[0028] 1 Materials and methods

[0029] 1.1 Animals and grouping

[0030] 50 Kunming mice, male, weighing about 20 g. Certificate number: Anhui Medical Practice No. 01. Provided by the Experimental Animal Center of Anhui Medical University. Animals were randomly divided into 5 groups: blank control group; model control group; low-dose group (daily feeding 30mg / kg.bw bracken flavonoids group); medium dose group (daily feeding 90mg / kg.bw bracken flavonoids group) ; High-dose group (day feeding 180mg / kg.bw bracken flavone group).

[0031] 1.2 Extraction of crude flavonoids from bracken and determination of flavonoids content

[0032] Fresh bracken is baked ...

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Abstract

The invention relates to a method for using bracken chromocor extractive to prepare the drug used to discharge lead and release the lead poison, wherein, each day and each kilogram can use 30-180mg drug, to obtain significant lead discharge effect. And each day and each kilogram can use 50-300mg bracken chromocor to obtain significant lead poison release effect. The inventive drug will not discharge needed element of human body, while the bracken chromocor extractive contains the needed elements as iron and zinc of people.

Description

technical field [0001] The present invention relates to the use of bracken flavone extract. Background technique [0002] Lead is a harmful metal and has no physiological effect in the human body. The ideal blood lead concentration should be zero. However, with the rapid development of modern industry and modern transportation, environmental lead pollution is becoming more and more serious, seriously endangering human health. Lead is a blue-gray metal that is a non-degradable environmental pollutant. It can accumulate in the environment for a long time. It can absorb lead through water, air, food, etc. through the mouth, respiratory tract, gastrointestinal tract, and skin. Some of it accumulates in the human body for a long time. If it cannot be completely excreted, it will cause damage to the human nervous, hematopoietic, immune, digestive and other systems and various organs of the human body to varying degrees, resulting in chronic poisoning. Compared with adults, child...

Claims

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Application Information

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IPC IPC(8): A61K36/11A61P39/02A61P43/00A61K125/00
Inventor 陈乃富张莉陈存武韩邦兴谷仿丽李耀亭
Owner WEST ANHUI UNIV
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