Gluconic acid cobalt and method of preparing the same

Abstract

Gluconic cobalt and the production method relate to a cobalt-containing organic compound, gluconic cobalt, suitable for pharmaceutical intermediates and the production method. The present invention aims to solve the problem that the current domestic and foreign markets have no gluconic cobalt. The chemical formula is C12H22CoO14. In the production method, the cobalt sulphate and sodium bicarbonate are respectively dissolved in water to prepare saturated solution; the saturated solution is filtered and refined; the mixture reacts in a reactor; the reaction temperature is controlled at 80 DEG C; after one hour, the mixture is arranged in another container to be statically laid for 12 hours; the following process comprises the centrifugal separation, washing, drying, crushing, and screening. The chemical reaction formula is 5CoSO4question mark 7H2O+10NaHCO3arrow 2CoCO3question mark 3Co(OH)2+5Na2SO4+8CO2. Then the prepared alkali cobalt carbonate and glucose acid react in the reactor for one hour at a temperature between 70 and 100 DEG C; the products are then arranged in a crystallization slot for crystallization, drying and crushing. The present invention has the advantages of easy solubility in water and simple production process.

Description

[technical field] [0001] The invention relates to a cobalt-containing organic compound cobalt gluconate suitable for use as a pharmaceutical intermediate and a production method thereof. [Background technique] [0002] At present, the pharmaceutical industry is in urgent need of an ideal cobalt-containing organic compound suitable for use as a pharmaceutical intermediate, but it has not been sold in the domestic and foreign markets so far, and no relevant reports have been seen. [Content of the invention] [0003] The object of the present invention is to provide a kind of cobalt-containing organic compound cobalt gluconate suitable for making medicine intermediate and production method thereof. [0004] The purpose of the present invention is achieved like this: the first step is produced basic cobalt carbonate, and method is to dissolve cobalt sulfate and sodium bicarbonate respectively in water, make saturated aqueous solution, and filter and prepare respectively, and r...

AI Technical Summary

Problems solved by technology

[0002] At present, the pharmaceutical industry is in urgent need of an ideal cobalt-containing organic compound suitable for pharmaceutical intermediates, but it has not been sold in the domestic and foreign markets so far, and no relevant reports have been seen.