New medicament usage of paeonol unction

A technology of paeonol and ointment, which is applied in the new medical field of paeonol ointment, which can solve the problems of many side effects, difficult acceptance by patients, and poor taste of medicine

Inactive Publication Date: 2008-04-09
HEFEI LIFEON PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most of the clinical treatments for acne use antibiotics for anti-inflammation, anti-androgen endocrine regulation, and retinoic acid drugs (with anti-keratinization, inhibition of sebaceous gland differentiation and sebum production, anti-inflammation, inhibition of collagenase synthesis in skin tissue, immune regulation, etc.) Although it has a certain clinical effect, it has many side effects, such as the impact on liver function, rough skin, and adverse reactions to the central nervous system. Women's use may even cause congenital deformities in babies.
Traditional Chinese medicine often uses products for clearing away heat and detoxifying, softening and dispelling stagnation, commonly used for oral treatment such as Loquat Qingfei Decoction, Wuwei Xiaodu Decoction, etc. Because of its poor taste and taste, patients are not easy to accept

Method used

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Embodiment Construction

[0009] The clinical and results of paeonol ointment in the treatment of adolescent acne vulgaris are described as follows:

[0010] Randomly divided 205 adolescent patients with acne vulgaris into a treatment group of 104 cases and a control group of 101 cases. The treatment group was treated with paeonol ointment, while the control group was treated with Zeping Fencijing.

[0011] 1 Clinical data Among the 104 cases in the treatment group, there were 56 males and 48 females; the average age was (19.97±2.56) years; the average disease duration was (4.05±1.68) years. Among the 101 cases in the control group, there were 52 males and 49 females; the average age was (20.04±1.98) years; the average disease duration was (3.85±0.93) years. There was no significant difference in gender, age, clinical manifestations and other data between the two groups after statistical processing (P>0.05), and they were comparable.

[0012] 1.1 The diagnostic criteria are drawn up with reference to ...

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Abstract

The invention relates to new medical use of paeonol ointment, namely, the application of the paeonol ointment for preparing a medicine for treating common acne. Acne is a chronic and phlogistic skin disease of hair follicles and sebaceous glands. In Western medicines, antibiotics and antiandrogen for incretion regulation, and retinoic acid medicines are commonly used, although the medicines have curative effect, side effects are in a large amount, and misuse of the medicines by female can cause congenital malformation to infants. In Chinese medicines, loquat lung clearing decoction and antiphlogistic decoction of five drugs are commonly used for peroral treatment, but have suboptimal taste, thereby being uneasily accepted by patients. The paeonol ointment is an antiallergic medicine for external use, and applicants use the paeonol ointment for treating acne, with the total effectiveness ratio of 100 percent.

Description

1. Technical field [0001] The invention relates to a new application of a known substance, in particular to a new medical application of paeonol ointment. 2. Background technology [0002] Paeonol ointment is a variety recorded in the tenth volume of Chinese patent medicine preparations in the "Drug Standards of the Ministry of Health", and it is composed of raw materials such as paeonol and clove oil. Clinically used for anti-allergic, anti-inflammatory and antipruritic effects. It is mainly used for various skin diseases caused by allergies, such as eczema, dermatitis, hives, itchy skin, redness and swelling caused by mosquito bites, and the curative effect is exact. The causes of dermatitis, eczema, and urticaria include internal and external factors: the so-called internal factors are the allergic constitution of the patient itself, or the instability of the internal environment such as chronic digestive system diseases, mental stress, insomnia, excessive fatigue, emoti...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K9/06A61P17/10A61K31/12
Inventor 季俊虬高美华季永明
Owner HEFEI LIFEON PHARMA
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