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Use of extract of non-fruit part of prune tree

A technology of extracts and uses, applied in the application field of medicine and health food

Active Publication Date: 2012-05-23
HANGZHOU U MATE TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, according to the characteristics of acute gout, there are no drugs that have significant curative effects in anti-inflammatory, analgesic and uric acid-lowering aspects.

Method used

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  • Use of extract of non-fruit part of prune tree
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  • Use of extract of non-fruit part of prune tree

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] Green Plum Extract

[0110] The flowers of Prunus mume 'Da Ye Qing', Xiaoshan Daqingmei variety, were collected, dried, pulverized into coarse powder of about 10 mesh, and 15kg was taken into a supercritical extraction kettle for extraction.

[0111] Extraction conditions: extraction pressure 35MPa, extraction temperature 60°C, separation temperature 40°C, separation pressure 4MPa, cyclic dynamic extraction for 2 hours, 720g of plum blossom fat-soluble extract (Dietmate Fructus) was obtained in the separation kettle. TM (Trademark of Hangzhou Umate Technology Co., Ltd.)-F01).

[0112] By GC-MS analysis, it mainly contains long-chain alkanes, polyolefins, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (tricosahexaene) in the fat-soluble effective part is 1.04% by mass.

[0113] The raffinate was taken out from the extraction kettle, and the raffinate was extracted by 30% ethanol-water solution under reflux.

[0114] E...

Embodiment 2

[0118] Green Plum Branch Extract

[0119] The branches of Prunus mume 'Xi Ye Qing' of Xiaoshan Daqingmei variety were collected, dried, pulverized into coarse powder of about 10 meshes, and 15kg was taken into a supercritical extraction kettle for extraction.

[0120] Extraction conditions: extraction pressure 30MPa, extraction temperature 55°C, separation temperature 45°C, separation pressure 4MPa, cyclic dynamic extraction for 2 hours to obtain 645g (Dietmate TM -B01).

[0121] By GC-MS analysis, it mainly contains long-chain alkanes, polyolefins, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (tricosahexaene) in the fat-soluble effective part is 4.87% by mass.

[0122] The raffinate was taken out from the extraction kettle, and the raffinate was extracted by 30% ethanol-water solution under reflux.

[0123] Extraction conditions: temperature 80° C., material-liquid ratio 1:15 (W / V), reflux extraction for 2 hours], to obt...

Embodiment 3

[0127] Green Plum Leaf Extract

[0128] The leaves of Xiaoshan Daqingmei variety Hongding (Prunus mume 'Hong Ding') were collected, dried, pulverized into coarse powder of about 10 meshes, and 15 kg were taken into a supercritical extraction kettle for extraction.

[0129] Extraction conditions: extraction pressure 35MPa, extraction temperature 55°C, separation temperature 40°C, separation pressure 6MPa, cyclic dynamic extraction for 2 hours to obtain 975g of plum leaf fat-soluble extract (Dietmate TM -L01).

[0130] By GC-MS analysis, it mainly contains long-chain alkanes, polyolefins, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (tricosahexaene) in the fat-soluble effective part is 44.15% by mass.

[0131] The raffinate was taken out from the extraction kettle, and the raffinate was extracted by 30% ethanol-water solution under reflux.

[0132] Extraction conditions: the temperature is 70 ° C, the ratio of material to l...

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PUM

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Abstract

The invention discloses application of plum extract in gout. The application can be realized by decreasing blood uric acid, reducing blood fat and / or inhibiting inflammation. The invention also discloses application of plum extract in treating and preventing hyperuricemia, and the application can result in effects of treating or preventing gout.

Description

technical field [0001] The present invention relates to the field of medicine and health food. More specifically, it relates to the application of extracts of plum blossoms, plum branches, plum stems, plum roots and plum leaves in the preparation of medicines and health foods for preventing and treating hyperuricemia and gout. Background technique [0002] Plum is a plant of the Rosaceae family, scientific name Prunus mume Sieb.Et Zucc. In horticultural cultivation, plums are divided into flower plums and fruit plums, and fruit plums are divided into white plums, green plums and red plums. [0003] WO00 / 39249 (PCT / JP99 / 07285) discloses a medicinal plum extract and a composition containing the extract, wherein the following content is disclosed: "Using 5 times the volume of methanol, from the stems and leaves of plum Extracts prepared from the nuts and plum blossoms of Prunus cerevisiae, the extracts have antioxidant effects, gastric mucosal damage inhibition, aldose reducta...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61K9/00A61P19/06A61P29/00A61P3/06C07B63/00C07C7/10C07C67/58C07D311/30C07J9/00C07J63/00A61K135/00A61K133/00A61K127/00A61K125/00
Inventor 张英陆柏益吴晓琴夏道宗张泳华刘志河
Owner HANGZHOU U MATE TECH
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