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Use of extract of non-fruit part of prune tree

A technology of extract and use, applied in the application field of medicine and health food

Active Publication Date: 2008-06-04
HANGZHOU U MATE TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, according to the characteristics of acute gout, there are no drugs that have significant curative effects in anti-inflammatory, analgesic and uric acid-lowering aspects.

Method used

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  • Use of extract of non-fruit part of prune tree
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  • Use of extract of non-fruit part of prune tree

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] Plum Blossom Extract

[0110] The flowers of Xiaoshan plum variety Prunus mume ‘Da Ye Qing’ are collected, dried, crushed into a coarse powder of about 10 mesh, and 15 kg is extracted in a supercritical extraction kettle.

[0111] Extraction conditions: extraction pressure 35MPa, extraction temperature 60°C, separation temperature 40°C, separation pressure 4MPa, circular dynamic extraction for 2 hours, 720g of plum blossom fat-soluble extract was obtained in the separation kettle (Dietmate TM (Trademark of Hangzhou Youmate Technology Co., Ltd.)-F01).

[0112] By GC-MS analysis, it mainly contains long-chain alkanes, polyenes, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (squalene) in the fat-soluble effective part is 1.04% by mass fraction.

[0113] The raffinate was taken out from the extraction kettle, and the raffinate was extracted with 30% ethanol-water solution under heat reflux.

[0114] Extraction condition...

Embodiment 2

[0118] Plum Branch Extract

[0119] The branches of Prunus mume 'Xi Ye Qing', a Xiaoshan plum variety, were collected, dried, and crushed into a coarse powder of about 10 meshes, and 15 kg was extracted in a supercritical extraction kettle.

[0120] Extraction conditions: extraction pressure 30MPa, extraction temperature 55°C, separation temperature 45°C, separation pressure 4MPa, circular dynamic extraction for 2 hours to obtain 645g of plum branch fat-soluble extract (Dietmate TM -B01).

[0121] By GC-MS analysis, it mainly contains long-chain alkanes, polyenes, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (squalene) in the fat-soluble effective part is 4.87% by mass fraction.

[0122] The raffinate was taken out from the extraction kettle, and the raffinate was extracted with 30% ethanol-water solution under heat reflux.

[0123] Extraction condition: temperature 80 ℃, solid-liquid ratio 1: 15 (W / V), reflux extraction ...

Embodiment 3

[0127] Plum Leaf Extract

[0128] The leaves of Prunus mume 'Hong Ding' from Xiaoshan are collected, dried, and crushed into a coarse powder of about 10 meshes, and 15 kg is extracted in a supercritical extraction kettle.

[0129] Extraction conditions: extraction pressure 35MPa, extraction temperature 55°C, separation temperature 40°C, separation pressure 6MPa, circular dynamic extraction for 2 hours to obtain 975g of plum leaf fat-soluble extract (Dietmate TM -L01).

[0130] By GC-MS analysis, it mainly contains long-chain alkanes, polyenes, V E , phytosterols and triterpenoids, wherein the content of the characteristic compound squalene (squalene) in the fat-soluble effective fraction is 44.15% by mass.

[0131] The raffinate was taken out from the extraction kettle, and the raffinate was extracted with 30% ethanol-water solution under heat reflux.

[0132] Extraction condition: temperature 70 ℃, solid-liquid ratio is 1: 12 (W / V), extract 3 hours], obtain plum leaf water...

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PUM

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Abstract

The invention discloses application of plum extract in gout. The application can be realized by decreasing blood uric acid, reducing blood fat and / or inhibiting inflammation. The invention also discloses application of plum extract in treating and preventing hyperuricemia, and the application can result in effects of treating or preventing gout.

Description

technical field [0001] The invention relates to the field of medicine and health food. More specifically, it relates to the application of extracts of plum blossom, plum branch, plum stem, plum root and plum leaf in the preparation of medicines and health food for preventing and treating hyperuricemia and gout. Background technique [0002] Plum is a plant of the family Rosaceae (Rosaceae), and its scientific name is Prunus mume Sieb.Et Zucc. In horticulture, plum is divided into flower plum and fruit plum, and fruit plum is divided into white plum, green plum and red plum. [0003] WO00 / 39249 (PCT / JP99 / 07285) discloses a medicinal plum extract and a composition containing the extract, which discloses the following content: "Using 5 times the volume of methanol, from the stems and leaves of plum The extract is prepared from the nuts and plum blossoms of plum, plum, and has antioxidative effect, gastric mucosal damage inhibitory effect, aldose reductase inhibitory effect, bl...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61K9/00A61P19/06A61P29/00A61P3/06C07B63/00C07C7/10C07C67/58C07D311/30C07J9/00C07J63/00A61K125/00A61K127/00A61K133/00A61K135/00
Inventor 张英陆柏益吴晓琴夏道宗张泳华刘志河
Owner HANGZHOU U MATE TECH
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