Guyinjian oral preparation and preparing method thereof

An oral preparation, Yin-deficiency technology, applied in the field of medicine, can solve problems such as inability to commercialize, inconvenient to carry and take, and inaccurate dosage

Inactive Publication Date: 2008-07-30
BEIJING JINFANGHUA MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The ancient "Guyin Decoction" did not only have a decoction, but it needs to be decocted and taken after purchasing decoction pieces. It is very inconvenient to carry and take it. After research, we have made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate and the quality is stable. , easy to take, suitable for large-scale commercial production, overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize, and is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1: Preparation method of "Guyin decoction" extract 1 (extract)

[0047] Prescription: 10g ginseng, 15g rehmannia, 24g yam, 15g dogwood, 20g dodder, 10g polygala, 10g schisandra, 10g roasted licorice

[0048] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6 to 15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, and combine the extracts; the water extracts stand still After 12-48 hours, filter the supernatant, concentrate under reduced pressure to obtain about 21.4 g of water extract.

Embodiment 2

[0049] Example 2: Preparation method of "Guyinjian" extract 2 (dry powder)

[0050] Prescription: 9g ginseng, 9g rehmannia, 9g yam, 9g dogwood, 9g dodder, 6g polygala, 6g schisandra, 6g roasted licorice

[0051] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8 to 10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts; the water extracts stand still After 12-48 hours, the supernatant was collected by filtration, concentrated under reduced pressure, and spray-dried to obtain about 18.1 g of water extract as a dry powder.

Embodiment 3

[0052] Embodiment three: "Guyin decoction" oral solid preparation preparation method

[0053] (1) Preparation of "Guyinjian" granules

[0054] prescription:

[0055] "Guyinjian" extract 1 10-90%

[0056] Starch 5.0-70%

[0057] Dextrin 2.0-20%

[0058] Xylitol 5.0-20%

[0059] Methyl sorbate 0.001-2.0%

[0060] Preferred Prescription:

[0061] "Guyinjian" Extract 1 21.4g

[0062] Starch 3.0g

[0063] Dextrin 10.0g

[0064] Xylitol 5.0g

[0065] Methyl sorbate 0.002g

[0066] Preparation method: prepare the extract of "Guyinjian" according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dry and pack.

[0067] (2) Preparation of "Guyin Decoction" tablet:

[0068] (1) Ordinary tablet prescription:

[0069] "Guyinjian" Extract 2 5.0-90%

[0070] Starch 5.0-50%

[0071] Dextrin 2.0-20%

[0072] Microcrystalline Cellulose 5.0-20%

[0073] Talc 0.5-5.0%

[0074] Magnesium stearate ...

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PUM

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Abstract

The invention relates to an oral preparation of consolidating-yin decoction medicine, which is prepared with ginseng and other seven Chinese medicines mainly for treating yin deficiency and emission, turbid leucorrhea and dribbling and non-consolidation of menses resulted from deficiency, and the preparation method thereof. The oral preparation is prepared according to the conventional processes and utilizing the mixed extracts as raw materials, such as ginseng, old land, Chinese yam, cornus officinalis, dodder, milkwort, schisandra chinensis and baked licorice, together with vector or excipient which are utilized as matrix and acceptable in pharmacy. The preparation has the effects of reinforcing kidney and regulating menstruation, and mainly treats yin deficiency and frequent diarrhea, turbid leucorrhea and dribbling and non-consolidation of menses resulted from deficiency. The long-term clinical application of the prescription shows that the preparation has good effects on menoxenia, dysfunctional uterine bleeding, infertility, amenorrhea and nocturnal emission, etc.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral preparation for mainly treating yin deficiency, slippery diarrhea, turbid stranguria, and menstrual fluid not solidified due to deficiency, and a preparation method thereof, in particular to taking the extract of the traditional Chinese medicine prescription of solid yin decoction as a medicine Oral formulation of the active ingredient. Background technique [0002] "Guyin Decoction" was created in "Jingyue Quanshu" by Zhang Jingyue in the Ming Dynasty. It has always been used as a common prescription for tonifying the kidney and regulating menstruation. , Indications for slippery diarrhea due to yin deficiency, with turbid stranguria and menstrual water due to deficiency and not solidification. The long-term clinical application of this prescription has shown that it has a good curative effect on the treatment of irregular menstruation, dysfunctional uterin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/48A61K9/20A61K9/16A61K9/10A61K9/28A61K9/46A61K47/38A61K47/34A61K47/32A61P15/00A61P15/08A61P13/12A61K47/10
Inventor 张文芳
Owner BEIJING JINFANGHUA MEDICAL SCI TECH
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