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System for evaluation of Chinese medicine numeralization color spectrum dactylogram similarity

A technology of similarity evaluation and fingerprint spectrum, which is applied in the field of similarity evaluation system of traditional Chinese medicine fingerprints, can solve problems such as difficulties in traditional Chinese medicine, achieve the effects of improving the comparability between peaks, making it easier to compare, and realizing dataization

Inactive Publication Date: 2008-09-03
WANNAN MEDICAL COLLEGE
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  • Description
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AI Technical Summary

Problems solved by technology

[0002] With the development of China's economy, the standardization of traditional Chinese medicine and its various products is becoming more and more important. The digital fingerprint of traditional Chinese medicine is an important part of the standardization of traditional Chinese medicine, but there are more or less digital fingerprints of traditional Chinese medicine from different origins. This makes it difficult for the drug supervision and drug inspection departments in different places to quickly judge the authenticity of traditional Chinese medicine.

Method used

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  • System for evaluation of Chinese medicine numeralization color spectrum dactylogram similarity
  • System for evaluation of Chinese medicine numeralization color spectrum dactylogram similarity
  • System for evaluation of Chinese medicine numeralization color spectrum dactylogram similarity

Examples

Experimental program
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Effect test

Embodiment 1

[0052] like figure 1 shown:

[0053] In steps 101-106, input the original database of authentic and inspected products detected by the high performance liquid chromatograph, and after performing one or more corrections on the sample data according to the retention time of the reference sample, a database of authentic and inspected products to be processed is formed, A genuine product in the genuine product library is set as the standard sample, and its data is used as the standard data. After the data of the other genuine products and the inspection products are matched with the standard data, the authentic product fingerprint atlas set and the inspection product fingerprint atlas set are formed;

[0054] In steps 107-110, in the fingerprint collection of the genuine product, n peaks with higher content are selected as n strong peaks, and chromatographic peaks with the same retention time of different samples are used as common peaks, and the common peaks account for the total...

Embodiment 2

[0061] Except that steps 113-117 are changed to steps 401-406, the rest is the same as that of Embodiment 1.

[0062] In steps 401-406, calculate the difference rate R of each sample in the authentic fingerprint database, and use the maximum difference rate R of the authentic product as the threshold to calculate the difference rate between the tested product and the authentic product. The difference rate R of the tested product 样 , judging the mean value of difference degree R 样 The mean value R of the degree of difference with the feature fingerprint database, if the difference rate of the inspected product is R 样 If it is less than the difference rate R in the authentic fingerprint database, it is a qualified product, and its data is added to the original database of the authentic product to increase the representativeness of the authentic fingerprint database. If the difference rate of the inspection product is R 样 If it is greater than the average similarity J in the aut...

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Abstract

The invention discloses a system for evaluating the similarity of digital chromatographic fingerprint of Chinese medicine, which includes the test of the substances by HPLC, input of the test result into the digital computer which saves programs, the digital computer which saves programs executes the following step: inputting data of quality goods and tested samples being tested by the HPLC into the original database, matching the data of quality goods and tested samples with the standard data, forming a quality goods fingerprint collection, a quality goods characteristic fingerprint database and a tested sample fingerprint collection; processing peak matches between the data in the tested sample fingerprint collection with the data in the quality goods characteristic fingerprint database, forming a tested sample fingerprint database, calculating the similarity between the quality goods and the similarity between the tested samples and every quality good, if the similarity mean of the tested samples is larger than the similarity mean J of the quality goods characteristic fingerprint database, the product is a qualified product, compared with the prior art, the peak-to-peak comparability is improved, the scientific processing is combined with integrity and fuzzyness, the datamation of the map is realized.

Description

technical field [0001] The invention belongs to a similarity evaluation system of traditional Chinese medicine fingerprints, in particular to a computer-based similarity evaluation system of digital fingerprints of traditional Chinese medicines. Background technique [0002] With the development of China's economy, the standardization of traditional Chinese medicine and its various products is becoming more and more important. The digital fingerprint of traditional Chinese medicine is an important part of the standardization of traditional Chinese medicine, but the digital fingerprints of traditional Chinese medicine of different origins exist more or less. The difference makes it difficult for drug administrations and drug inspection departments in different places to quickly judge the authenticity of traditional Chinese medicines. SUMMARY OF THE INVENTION [0003] The technical problem to be solved by the present invention is to provide a computer system that can quickly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/86G06F17/00
Inventor 邹纯才鄢海燕
Owner WANNAN MEDICAL COLLEGE
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