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Chinese medicinal composition for treating nephrotic syndrome and preparation thereof

A technology for nephrotic syndrome and composition, which is applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc.

Inactive Publication Date: 2008-09-10
BEIJING ZHONGTAI TIANHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine began to use hormones and immunosuppressants in the 1950s and 1960s, and in the 1970s, high-dose hormones were used for shock therapy. Although the fatality rate of this disease was reduced from 60% to 70% in the past to 4% to 7%, however, The ensuing toxic side effects cannot be ignored

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: Chinese medicine composition granule of the present invention

[0038] (1) 180g of Wujiapi is crushed into fine powder for later use;

[0039] (2) 260g of tangerine peel, 200g of motherwort, and 80g of Chinese yam were refluxed twice with 60% ethanol, each time for one hour, and filtered in stages, the combined filtrate was concentrated under reduced pressure into a clear paste with a relative density of 1.15 (60°C);

[0040] (3) Astragalus 160g, Salvia miltiorrhiza 80g, Codonopsis 80g, Atractylodes macrocephala 210g, Eucommia 130g, Eucommia 130g, Sangjisheng 180g, Yiren 130g, Imperata rhizome 180g, Poria cocos skin 200g, Xianling spleen 180g, Rehmannia glutinosa 160g, add water and decoct twice, each time After 2 hours, filter, combine the filtrates, let stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder, dry, grind into a fine powder, add lactose ...

Embodiment 2

[0041] Embodiment 2: Chinese medicine composition capsule of the present invention

[0042] (1) 180g of Wujiapi is crushed into fine powder for later use;

[0043] (2) 260g of tangerine peel, 200g of motherwort, and 80g of Chinese yam were refluxed twice with 60% ethanol, each time for one hour, and filtered in stages, the combined filtrate was concentrated under reduced pressure into a clear paste with a relative density of 1.15 (60°C);

[0044] (3) Astragalus 160g, Salvia miltiorrhiza 80g, Codonopsis 80g, Atractylodes macrocephala 210g, Eucommia 130g, Eucommia 130g, Sangjisheng 180g, Yiren 130g, Imperata rhizome 180g, Poria cocos skin 200g, Xianling spleen 180g, Rehmannia glutinosa 160g, add water and decoct twice, each time After 2 hours, filter, combine the filtrates, let stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder and clear paste, dry, and grind into fine po...

Embodiment 3

[0045] Embodiment 3: Chinese medicine composition tablet of the present invention

[0046] (1) 180g of Wujiapi is crushed into fine powder for later use;

[0047] (2) 260g of tangerine peel, 200g of motherwort, and 80g of Chinese yam were refluxed twice with 60% ethanol, each time for one hour, and filtered in stages, the combined filtrate was concentrated under reduced pressure into a clear paste with a relative density of 1.15 (60°C);

[0048] (3) Astragalus 160g, Salvia miltiorrhiza 80g, Codonopsis 80g, Atractylodes macrocephala 210g, Eucommia 130g, Eucommia 130g, Sangjisheng 180g, Yiren 130g, Imperata rhizome 180g, Poria cocos skin 200g, Xianling spleen 180g, Rehmannia glutinosa 160g, add water and decoct twice, each time After 2 hours, filter, combine the filtrates, let stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder and clear paste, dry, and grind into fine pow...

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PUM

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Abstract

The present invention relates to a Chinese medicine compound for curing nephropathy syndrome, which is made from milk veteh, dried orange peel, salvia, dangshen, largehead atractylode, cortex eucommiae, motherwort herb, gordon euryale seed, parasite scurrula, coix seed, Chinese yam, imperatae rhizome, poria skin, epimedium powder, slenderstyle acanthopanax bark, cooked rehmannia root and / or acceptable carriers in pharmacology. The present invention also relates to a preparation method of the Chinese medicine compound. The Chinese medicine compound of the present invention has the effects of reinforcing the spleen and replenishing qi, removing heat and toxic substance, promoting diuresis and eliminating dampness, nourishing liver and kidney, etc., which is used for curing such symptoms as a large amount of albuminuria, serious edema, hypoproteinemia and hyperlipidemia caused by nephropathy syndrome.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating nephrotic syndrome and a preparation method thereof. Background technique [0002] Nephrotic syndrome (NS) is not an independent disease, but a group of clinical syndromes in glomerular diseases. Typical manifestations are massive proteinuria (>3.5g / 1.73m2 body surface area per day), hypoalbuminemia (plasma albumin<30g / L), edema with or without hyperlipidemia, and the diagnostic criteria should be a large amount of protein Urine and hypoalbuminemia. Massive proteinuria is characteristic of glomerular disease and is less common in renovascular disease or tubulointerstitial disease. Since hypoalbuminemia, hyperlipidemia, and edema are the consequences of massive proteinuria, it is believed that the diagnostic criteria should be based on massive proteinuria. [0003] Many diseases can cause damage to the gl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/48A61K9/16A61K9/20A61P13/12
Inventor 何俊保
Owner BEIJING ZHONGTAI TIANHE SCI & TECH
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