Method for screening high immunoglobulinlg IgG synthesizing ability lactation cow

Abstract

The invention discloses a method for screening lactating dairy cows with high immunoglobulin IgG synthesis capacity, the specific steps are as follows: (1) a milk sample of the dairy cow is collected; (2) the somatic cell number SCC, the milk fat rate, the milk protein, the lactose and the total solids of the collected milk sample are measured; (3) the somatic cell score SCS is obtained by utilizing the somatic cell number SCC for calculation; (4) the IgG index is calculated; (5) the dairy cows are screened: the dairy cows with the IgG index which is more than -4.3 are selected. The experiment shows that the method can accurately screen the dairy cows with high IgG content in the milk from the dairy herd, managers can clearly know the dairy cows with high IgG yield and carry out the centralized feeding of the dairy cows; compared with the dairy herd which is not screened, the IgG content in the milk product obtained can be greatly improved by more than 19.5 percent, and the feeding cost can be greatly reduced. The application of the method of the invention can remarkably improve the IgG content in the milk and can provide the possibility for the production of the milk which is rich in high immunoglobulin.

Description

technical field [0001] The invention relates to a method for screening dairy cows, in particular to a method for screening lactating dairy cows with high immunoglobulin IgG synthesis ability. Background technique [0002] Immunoglobulins are the most important immune active proteins in colostrum and milk. The immunoglobulins in milk mainly include IgG, IgM, and IgA. Immune colostrum or immune milk contains specific antibodies that can prevent and treat intestinal diseases, and can prevent some human infectious diseases, such as Shigella flexneri, Escherichia coli, Clostridium stubborn (Clostridium difficile), Cryptosporidium parvum, Streptococcus mutans, and Helicobacter pylori. The specific Ig in milk can effectively inhibit the reproduction of bacteria, inhibit bacterial colonization, inhibit the binding of substrates, inhibit the secretion of toxins from bacteria, prevent the binding of toxins to human cell receptors, neutralize toxins, and reduce bacterial activity. a...

AI Technical Summary

Problems solved by technology

However, the high production cost of immune milk and the special requirements of processing technology have become the restrictive factors for the further development of immune milk; the structure-activity relationship and molecular mechanism of many bioactive peptides are still unclear

The low concentration of bioactive peptides, complex enzymatic hydrolysis conditions, and difficulty in separation and purification have become the main factors restricting the industrial production of dairy deep processing technology; the production efficiency of transgenic animals is low, and the offspring of transgenic individuals cannot express or express chaotically and cannot be passed on to offspring, etc. Problems that limit the industrial production of immunologically active proteins

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