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Multichannel surface plasma wave sensing detection system

A technology of surface plasmon waves and detection systems, applied in the field of biosensors

Inactive Publication Date: 2011-07-06
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

[0005] In view of this, the purpose of the present invention is to provide a multi-channel surface plasmon wave sensing and detection system, which can overcome the complex operation and false positive rate existing in the prior art High and low throughput, poor specificity and other shortcomings, and various detection items, less time-consuming, high sensitivity, easy to carry, especially can fully meet the needs of use in complex environments, and has broad application prospects

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  • Multichannel surface plasma wave sensing detection system

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Embodiment Construction

[0034] figure 1 It is a structural schematic diagram of the present invention; figure 2 Schematic diagram for the coating of biological probes; image 3 It is a schematic diagram of photoelectric signal transmission; Figure 4 It is a schematic diagram of the control structure of the cruising adjustable light source. As shown in the figure, the present invention includes an SPR biosensing detection device, an incident light channel, an outgoing light channel and an intelligent analysis and processing platform 22:

[0035] Among them, the SPR biosensing detection device includes an SPR biosensor: the SPR biosensor includes a reaction cell 1, a lens I2 and a substrate 3, the reaction cell 1 is arranged on the upper part of the SPR biosensor, the lens I2 is arranged on the lower part of the SPR biosensor, and the substrate 3 is arranged on the SPR biosensor. Between the reaction pool 1 and the lens I2, a metal film 4 is provided on the substrate 3, and the metal film 4 is ke...

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Abstract

The invention discloses a multi-channel surface plasma wave sensing-monitoring system, which comprises a SPR biological sensing-monitoring device, an incident light channel, an exit light channel and an intelligent analysis processing platform, wherein the SPR biological sensing-monitoring device comprises a SPR biological sensor and an adjustable detecting light source, the incident light channel comprises a cruising adjustable polarized light source which comprises a polarized light source and a control system, and the exit light channel comprises a convergent lens and a photodetector. The multi-channel surface plasma wave sensing-monitoring system can accurately analyze the interaction (the function of multiple factors) of various matters in specimens, avoids system deviation which is brought by single measurement, greatly reduces monitoring time, and improves monitoring efficiency. The invention has the advantages of compact structure, convenient carrying, convenient employment and high sensitiveness, which can be applied in a plurality of fields and various environments, and has wide application prospect.

Description

technical field [0001] The invention relates to the field of biosensors, in particular to a multi-channel surface plasmon wave sensing and detection system. Background technique [0002] Surface plasmon resonance (SPR) is a physical optics phenomenon. Surface plasmon resonance detection is a detection technology using surface plasmon waves (SPW, Surface Plasma Wave), which has the advantages of no labeling, high speed, specificity, high sensitivity, and a large number of parallel screening. Surface plasmons (SP) are formed by electromagnetic waves propagating along the interface between a metal and a dielectric. When the polarized light parallel to the surface is incident on the interface at an angle called surface plasmon resonance, when attenuated total reflection occurs, the incident light is coupled into the surface plasmon, and a large amount of light energy is absorbed. At this angle, due to the surface plasmon resonance Causes a significant reduction in reflected li...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/55G01N21/41G01N21/552
Inventor 王珏罗阳府伟灵
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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