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Preparation of D-chiro-inositol in mungbean sprout

A technology of chiral inositol and mung bean sprouts extract, applied in the field of bioengineering, can solve the problems such as the inability of patients to produce enough D-chiro-inositol and the obstruction of insulin signal transmission.

Inactive Publication Date: 2009-05-20
INST OF CROP SCI CHINESE ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have found that blood and urine of normal people contain a certain concentration of D-chiro-inositol, but it is almost undetectable in patients with type II diabetes. Therefore, these patients may not be able to produce a sufficient amount of D-chiro-inositol. block insulin signaling

Method used

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  • Preparation of D-chiro-inositol in mungbean sprout
  • Preparation of D-chiro-inositol in mungbean sprout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Biological method for significant conversion of D-chiro-inositol derivatives to D-chiro-inositol in mature mung bean seeds.

[0013] Observe the effects of different conditions and germination time of mung bean seeds on the content of D-chiroinositol as shown in the following table 1:

[0014] Table 1:

[0015] germination time

[0016] It is concluded from Table 1 that under the condition of 10mM NaCl, mung beans germinated for 36 hours have the highest concentration of D-chiro-inositol, which is suitable for the prevention and treatment of diabetes.

Embodiment 2

[0017] Example 2, extracting mung bean seed dry powder rich in the conversion of D-chiroinositol of the present invention

[0018] single factor test

[0019] 2.1 Investigate the influence of temperature on the extraction rate (fixed ethanol concentration 50%, extraction time 30 minutes), the results are shown in the following table 2:

[0020] Table 2

[0021] extraction temperature 30 degrees 40 degree 50 degrees 60 degrees 80 degrees Yield 2.9％ 4.1％ 4.7％ 3.5％ 3.1％

[0022] 2.2 Investigate the influence of ethanol concentration on the extraction rate (fixed temperature 40 degrees, extraction time 30 minutes), the results are shown in the following table 3:

[0023] table 3

[0024] ethanol concentration 40％ 60％ 70％ 80％ 100％ Yield 1.13％ 1.46％ 1.80％ 2.02％ 1.24％

[0025] 2.3 Investigate the influence of extraction time on extraction rate (fixed temperature 40 degrees, ethanol concentration 50%), the results are ...

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Abstract

The invention provides a method for extracting a functional component of mungbean sprout. The obtained extract has remarkable function of reducing blood sugar and can be used to prepare a drug for treating diabetes or health-care food for preventing and treating diabetes.

Description

technical field [0001] The invention relates to the technical field of bioengineering, and provides a method for extracting D-chiroinositol from mung bean sprouts, and the obtained extract has a significant function of lowering blood sugar, and can be used to prepare antidiabetic drugs or health food for preventing and treating diabetes . Background technique [0002] Mung bean (Vinga radiata L.) belongs to a cultivated species in the phaseoleae (phaseoleae) Vigna plant. It has a cultivation history of more than 2,000 years in my country and is rich in resources and various in variety. Traditional Chinese medicine has elaborated on the medicinal effects of mung beans. It is recorded in "Kaibao Materia Medica": "Mung beans are sweet, cold, and non-toxic. Enter the heart and stomach meridian. Mainly erysipelas, irritability, heat, rubella, hot air rushing to the porpoise, raw grinded twisted juice is taken , also cook food, reduce swelling and relieve qi, press heat and detox...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61K9/08A61K9/10A61K9/20A61K9/48A61P3/10A23L1/172A23L1/30A61K131/00A23L33/105
Inventor 任贵兴么杨张瑞秦培友侯召华
Owner INST OF CROP SCI CHINESE ACAD OF AGRI SCI
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