Application of Bochmeria clidemioides Miq var diffusa, ramie capsules, particles and tablets, and preparation method thereof

Abstract

The invention discloses application of Bochmeria clidemioides Miq var diffusa (Weddffanc Mazz) in treating hemorrhoid, and a preparation method of a Chinese medicine historical preparation taking the Bochmeria clidemioides Miq var diffusa as a monarch drug and bear gall powder according to a mixture ratio of 190-210:1 by weight. The Bochmeria clidemioides Miq var diffusa has the functions of clearing away heat and toxic material, detumescence and hemostasis; and toxicological experiments prove that the preparation is nearly non toxic, and is a new Chinese medicine for deeply development. The invention also discloses a method for preparing various Chinese medicine historical preparations according to the conventional production method in the pharmaceutical field by the Bochmeria clidemioides Miq var diffusa as the monarch drug and the bear gall powder according to the mixture ratio of 190-210:1 by weight, wherein as a preferable mode, the preparation is a capsule, and is used for treating various hemorrhoid diseases. The preparations and the method not only provide a new Chinese medicine, but also provide a Chinese medicine historical preparation using the Chinese medicine as the monarch drug, the preparation has excellent treatment effect to reduce the economical burden of a patient, meanwhile, as the preparation is an oral preparation, patient use is greatly facilitated.

Description

technical field

[0001] The invention relates to a new medicinal Chinese medicinal material, in particular to the application of ramie ramie in the treatment of various hemorrhoid diseases. Simultaneously, the present invention also relates to a formula and a preparation method of a traditional Chinese medicine preparation using ramie ramie as the main medicine. technical background

[0002] Hemorrhoids are a unique disease of human beings, and the population of hemorrhoids is very large, which seriously affects the quality of life of human beings. The most effective method for treating hemorrhoids at present is surgical therapy, which brings pain and heavy economic burden to patients. Except the operation, some suppositories for external use are also commonly used to relieve symptoms. Most of the present suppositories cannot cure hemorrhoids, and they are inconvenient to use, which are only a helpless choice for people. Contents of the invention

[0003] The object of...

Examples

Embodiment 1

[0013] Take 4750g of ramie ramie, add 47500g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put them into capsules, or pack them into bags, or press them into tablets to get the finished product .

Embodiment 2

[0015] Take 5000g of ramie ramie, add 50000g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put it into capsules, or bag it, or press it into tablets to get the finished product .

Embodiment 3

[0017] Take 5250g of ramie ramie, add 52500g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put them into capsules, or pack them into bags, or press them into tablets to get the finished product .

[0018] The drug effect test was carried out by rat ankle edema method: 20 healthy rats with a body weight of 120-150g were taken, and the rats were divided into two groups, 10 rats in each group. Concentrate 0.1ml, the second group as a blank control. After 30 minutes, 0.1 ml of 1% carrageen solution (inflammatory agent) was subcutaneously injected into the ankle of the hind limb. Using capillary amplification to measure the volume of ...

technical field

[0001] The invention relates to a new medicinal Chinese medicinal material, in particular to the application of ramie ramie in the treatment of various hemorrhoid diseases. Simultaneously, the present invention also relates to a formula and a preparation method of a traditional Chinese medicine preparation using ramie ramie as the main medicine. technical background

[0002] Hemorrhoids are a unique disease of human beings, and the population of hemorrhoids is very large, which seriously affects the quality of life of human beings. The most effective method for treating hemorrhoids at present is surgical therapy, which brings pain and heavy economic burden to patients. Except the operation, some suppositories for external use are also commonly used to relieve symptoms. Most of the present suppositories cannot cure hemorrhoids, and they are inconvenient to use, which are only a helpless choice for people. Contents of the invention

[0003] The object of...

Examples

Embodiment 1

[0013] Take 4750g of ramie ramie, add 47500g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put them into capsules, or pack them into bags, or press them into tablets to get the finished product .

Embodiment 2

[0015] Take 5000g of ramie ramie, add 50000g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put it into capsules, or bag it, or press it into tablets to get the finished product .

Embodiment 3

[0017] Take 5250g of ramie ramie, add 52500g of water to decoct twice, then combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a thick paste with a relative density of 1.25-1.30. Then take the thick paste and dry it under reduced pressure, crush it into 200-300μm fine powder, add 25g of bear bile powder and mix well, then add dextrin with 20% of the weight of the medicine powder to make granules, put them into capsules, or pack them into bags, or press them into tablets to get the finished product .

[0018] The drug effect test was carried out by rat ankle edema method: 20 healthy rats with a body weight of 120-150g were taken, and the rats were divided into two groups, 10 rats in each group. Concentrate 0.1ml, the second group as a blank control. After 30 minutes, 0.1 ml of 1% carrageen solution (inflammatory agent) was subcutaneously injected into the ankle of the hind limb. Using capillary amplification to measure the volume of ...