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Plant drug compound preparation for treating asthma in children and preparation thereof

A compound preparation and a technology for children's asthma are applied in the field of a botanical compound preparation for the treatment of children's asthma and the field of preparation thereof, which can solve the problems of unsatisfactory treatment effect of children's asthma, aggravating airway inflammation and airway hyperresponsiveness and the like, and achieve good application. Prospect, no toxic side effects, high curative effect

Inactive Publication Date: 2009-10-21
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in clinical practice, many children cannot correctly grasp hormone inhalation therapy, and some parents are unwilling to use it because they are worried about the side effects of hormone use. Although bronchodilators can quickly control bronchospasm and relieve asthma, they sometimes aggravate the symptoms of asthma. Airway inflammation and airway hyperresponsiveness lead to the unsatisfactory treatment effect of children with asthma

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] (1) Take 6g of ephedra, 9g of almond, 9g of perilla, 9g of radish, 9g of earthworm, 6g of peach kernel, 9g of pepper, 9g of scutellaria baicalensis, 3g of raw licorice, soak in cold water for 20-30 minutes, and the amount of water covers the medicine surface , so that the drug is completely immersed in water;

[0031] (2) First decoct with strong fire until the water boils, then switch to slow fire and decoct for 15 minutes, then pour out the concoction;

[0032] (3) Continue to add cold water to cover the medicinal surface without soaking, repeat the operation of step (2), and combine the above-mentioned secondary decoctions to obtain the decoction;

[0033] (4) Let the above decoction stand, filter the supernatant, concentrate, let cool to obtain a concentrated solution, add 1-4 times the volume of alcohol, stir while adding, precipitate for 12-24 hours, and filter the supernatant , concentrated to a thick extract, added with pharmaceutical excipients, vacuum-dried, ...

Embodiment 2

[0035] (1) Take 9g of ephedra, 15g of almond, 15g of perilla, 15g of radish, 15g of earthworm, 9g of peach kernel, 15g of pepper, 15g of scutellaria baicalensis, 5g of raw licorice, soak in cold water for 20-30 minutes, and the amount of water covers the medicine surface That’s it, then press all the medicines down to make the medicines all immerse in the water;

[0036] (2) First decoct with strong fire until the water boils, then switch to slow fire and decoct for 15 minutes, then pour out the concoction;

[0037] (3) Continue to add cold water to cover the medicinal surface without soaking, repeat the operation of step (2), and combine the above-mentioned secondary decoctions to obtain the decoction;

[0038](4) Let the above decoction stand, filter the supernatant, concentrate, let cool to obtain a concentrated solution, add 1-4 times the volume of alcohol, stir while adding, precipitate for 12-24 hours, and filter the supernatant , concentrated to a thick extract, added ...

Embodiment 3

[0040] (1) Take 4g of ephedra, 6g of almond, 6g of perilla, 6g of radish, 6g of earthworm, 4g of peach kernel, 6g of pepper, 6g of scutellaria baicalensis, 2g of raw licorice, soak in cold water for 20-30 minutes, and the amount of water covers the medicine surface That’s it, then press all the medicines down to make the medicines all immerse in the water;

[0041] (2) First decoct with strong fire until the water boils, then switch to slow fire and decoct for 15 minutes, then pour out the concoction;

[0042] (3) Continue to add cold water to cover the medicinal surface without soaking, repeat the operation of step (2), and combine the above-mentioned secondary decoctions to obtain the decoction;

[0043] (4) Let the above decoction stand, filter the supernatant, concentrate, let cool to obtain a concentrated solution, add 1-4 times the volume of alcohol, stir while adding, precipitate for 12-24 hours, and filter the supernatant , concentrated to a thick extract, added with ...

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PUM

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Abstract

The invention relates to a plant drug compound preparation for treating asthma in children, which comprises water extracts of the following raw materials: 1 to 8 percent of mix-fried ephedra, 1 to 12 percent of almond, 1 to 12 percent of perilla fruit, 1 to 12 percent of radish seed, 1 to 12 percent of earthworm, 1 to 8 percent of peach kernel, 1 to 12 percent of zanthoxylum seed, 1 to 12 percent of baical skullcap root, and 1 to 5 percent of raw licorice; and the preparation of the plant drug compound preparation comprises that: composition of the plant drugs in the proportion is soaked in cold water for 20 to 30 minutes, decocted by intense fire to be boiled, and then decocted by slow fire for 15 minutes, drug juice is poured out, and the operation is repeated, and decoction liquid of the twice is combined to obtain decoction; and the decoction is stood, supernatant fluid is filtered, condensed, cooled naturally, and added with alcohol of which the volume is 1 to 4 times of that of the supernatant fluid, the mixture is precipitated, supernatant fluid is filtered and condensed to thick extract, and the thick extract is added with pharmaceutic adjuvant. The invention also relates to application of the plant drug compound preparation in preparing related medicaments for treating the asthma in children. The plant drug compound preparation has the advantages of high curative effect, no toxic and side effects, low price and the like; and the preparation method is simple, and has low cost and good application prospect.

Description

technical field [0001] The invention belongs to the field of herbal medicine compound preparation for treating asthma and its preparation, in particular to a herbal medicine compound preparation for treating children's asthma and its preparation. Background technique [0002] Asthma is a common and frequently-occurring disease in children. According to the survey, there are about 160 million asthma patients in the world, and the number of patients in my country is more than 20 million. In 2000, the prevalence rate of urban children aged 0 to 14 in my country was 0.5 to 3.4%, with an average of 1.97%, and it showed an increasing trend year by year. The main characteristics of asthma are chronic airway inflammation and airway hyperresponsiveness, manifested as recurrent symptoms such as wheezing, shortness of breath, chest tightness, and coughing, which can affect the lung function of children and, in severe cases, can be life-threatening. Western medicine mainly adopts meth...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P11/06A61K35/64A61K35/62
Inventor 虞坚尔吴杰
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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