Medical prescription of catalpol freezing-drying powder for injection and preparation method

Abstract

The invention relates to a medical prescription of catalpol freezing-drying powder for injection and a preparation method thereof. The invention is characterized in that the medical prescription of the catalpol freezing-drying powder for injection comprises 1 to 1000 mg of catalpol, 50mg to 2000mg of mannite, 100mg to 4000mg of glycine, 25mg to 1000mg of fucose, and 10% of sodium hydroxide solution right amount (pH 6.8-7.0). The invention also contains the medicinal application of the catalpol freezing-drying powder for injection which is used for treating clinical ischemia cerebral disease. The invention also comprises accessories used in the prescription which are used for preparing the catalpol and the freezing-drying powder for injection of the composition which is prepared by the catalop and other medicines according to different mixing ratios and is used for treating the ischemia cerebral disease. The invention aims at providing the traditional Chinese medicine active ingredient medicinal preparation. The preparation can permeate the blood brain barrier, alleviates the injury degree of the cerebral ischemia, increases the tolerance capability of the ischemia and oxygen-poor of brain tissues, promotes the newborn and the mature of brain microvascular, protects neurovascular units, promotes the neuron axon and dendrite growth, strengthens the synapse reconstruction, improves the back neutral behaviors of the cerebral ischemia, increases the neutral function score, and promotes the motor function recovery of affected limbs after the cerebral ischemia.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations. Specifically, the invention relates to a prescription and a preparation method of a freeze-dried powder injection of catalpol, an active ingredient of the traditional Chinese medicine rehmannia glutinosa, and is used for treating clinical cerebral ischemic brain diseases. Background technique [0002] Cerebrovascular disease is one of the main diseases that seriously endanger human health. With the aging of today's society, the incidence of cerebrovascular disease continues to increase. Among the 57 countries surveyed by the United Nations World Health Organization, 11.3 people died of cerebrovascular disease %, cerebrovascular diseases accounted for the top three causes of death in 40 countries. In my country, more people die of cerebrovascular disease than heart disease and cancer, ranking first among the three major causes of death, about 1 million people every year. ...

AI Technical Summary

Problems solved by technology

However, the therapeutic targets of these drugs are single, and the side effects are relatively large, so it is difficult to achieve satisfactory results.