Application of Chinese medicinal composition in preparation of medicament for treating acute nephritis

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, drug delivery, anti-infective drugs, etc., can solve the problems of undisclosed traditional Chinese medicine composition application, etc., achieve significant curative effect, relieve symptoms, and eliminate pathogenic factors

Active Publication Date: 2010-02-03
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese

Method used

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  • Application of Chinese medicinal composition in preparation of medicament for treating acute nephritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] prescription:

[0069] Forsythia 255g Honeysuckle 255g Radix Radix 255g Rhubarb 51g

[0070] Patchouli 85g Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g

[0071] 85 grams of ephedra, 85 grams of fried bitter almonds, 255 grams of Houttuynia cordata, 85 grams of licorice

[0072] Gypsum 255 grams.

[0073] Preparation:

[0074] (1) Take Chinese medicinal materials according to the above-mentioned prescription, and cleanly select them;

[0075] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0076] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract 2 times with 8 times the amount of 70% ethanol, the first time for 2 hours, the second time for 1.5 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for subseque...

Embodiment 2

[0082] prescription:

[0083] Forsythia 200g Honeysuckle 300g Radix Radix 200g Rhubarb 60g

[0084] Patchouli 60g Mianma Guanzhong 300g Rhodiola 60g Menthol 9g

[0085] Ephedra 60g Bitter almond 100g Houttuynia cordata 200g Licorice 100g

[0086] Gypsum 200 grams.

[0087] Preparation:

[0088] (1) Take Chinese medicinal materials according to the above-mentioned prescription, and cleanly select them;

[0089] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0090] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extracted twice with 6 times the amount of 50% ethanol, the first time for 1 hour, the second time for 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was used for subsequent use;

[0091] (4) Honeysuckle, gypsu...

Embodiment 3

[0096] prescription:

[0097] Forsythia 300g Honeysuckle 200g Radix Radix 300g Rhubarb 60g

[0098] Patchouli 100g Mianma Guanzhong 200g Rhodiola 60g Menthol 5g

[0099] Ephedra 100g Bitter almond 60g Houttuynia cordata 300g Licorice 60g

[0100] Gypsum 300 grams.

[0101] Preparation:

[0102] (1) Take Chinese medicinal materials according to the above-mentioned prescription, and cleanly select them;

[0103] (2) Patchouli is broken, add 8 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0104] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract 2 times with 10 times the amount of 90% ethanol, the first time is 3 hours, the second time is 2.5 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for subsequent use;

[0105] (4) Honeysuckle, gypsum, ...

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PUM

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Abstract

The invention discloses application of Chinese medicinal composition in preparation of medicament for treating acute nephritis. The Chinese medicinal composition mainly comprises weeping forsythiae capsule, honeysuckle flower, indigowoad root, rhubarb, cablin potchouli herb, male fern rhizome, rhodiola rosea, and the like. The Chinese medicinal composition takes the advantages of integrated regulation of compound Chinese medicament, organically combines the functions of dispelling disease evil, relieving symptoms and regulating immune, realizes multi-target treatment, and is proved by clinical experiments to have remarkable effect of treating the acute nephritis.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating acute nephritis, and belongs to the field of Chinese herbal medicines. Background technique [0002] Acute nephritis is a group of diffuse glomerular diseases triggered by immune reactions caused by various reasons. Clinically, it has acute onset, mainly manifested as hematuria, hypertension and edema, often accompanied by oliguria and glomerular filtration rate Reduced, also known as acute nephritic syndrome. Acute nephritis can occur at any age, including infants, but it is more common in children and adolescents aged 5-15, less than 10% in adults over 40 years old, and the ratio of male to female is about 2:10. [0003] Acute nephritis is mostly induced by infection, and group A R-hemolytic streptococcus is the most common, and it can also occur in other pathogens, such as bacteria (including: pneumococcus, meningococc...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61K9/48A61K9/20A61K9/14A61K9/16A61K9/10A61K9/02A61K9/12A61K9/00A61P13/12A61P31/00A61K33/06
Inventor 李向军安军永王超郑立发
Owner BEIJING YILING PHARMA
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