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Preparation method for coix seed oil microemulsion

A technology of Coix seed oil and microemulsion, which is applied in the field of preparation of traditional Chinese medicine microemulsion, can solve the problems of destruction of effective components of Coix seed oil, high process operation temperature, large amount of emulsifier, etc., and achieves convenient tissue production, low process operation temperature, good bioavailability

Inactive Publication Date: 2010-10-20
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The above-mentioned background technology has the disadvantages of large amount of emulsifier, high process temperature, complicated process, and damage to the active ingredients in coix seed oil to a certain extent.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Coix seed oil 0.4 grams, Tween 80 2 grams, Span 80 1 grams, ethanol 0.5 grams, distilled water 6.1 grams. Take 0.4 grams of coix seed oil, 2 grams of Tween 80, 1 gram of Span 80, 0.5 grams of ethanol, and 0.1 grams of isopropyl myristate in the same container, and stir and mix for 10 minutes at 40 degrees Celsius. Slowly add 6.1 grams of distilled water preheated to 40 degrees Celsius while stirring under stirring to obtain microemulsion.

Embodiment 2

[0014] Coix seed oil 0.5 grams, Tween 80 2 grams, Span 80 0.6 grams, ethanol 0.5 grams, distilled water 6.4 grams. Take 0.5 grams of coix seed oil, 2 grams of Tween 80, 0.6 grams of Span 80, 0.5 grams of ethanol, and 0.05 grams of ethyl oleate in the same container, and stir and mix for 10 minutes at 40 degrees Celsius. After uniformity, stir under magnetic stirring While slowly adding 6.4 grams of distilled water preheated to 40 degrees Celsius, the microemulsion is obtained.

Embodiment 3

[0016] Coix seed oil 0.5 grams, Tween 80 2 grams, lecithin 0.2 grams, n-butanol 0.2 grams, distilled water 7.1 grams. Take 0.5 grams of coix seed oil, 2 grams of Tween 80, 0.2 grams of lecithin, 0.2 grams of n-butanol, and 0.05 grams of isopropyl myristate in the same container, stir and mix for 10 minutes at 40 degrees Celsius, and after uniformity, Slowly add 7.1 grams of distilled water preheated to 40 degrees Celsius while stirring under magnetic stirring to obtain microemulsion.

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Abstract

The invention discloses a preparation method for a coix seed oil microemulsion. The coix seed oil microemulsion is a coix seed oil microemulsion system which consists of coix seed oil, composite emulsifiers, emulsifier aids, distilled water and the like. Each 100 milliliters of coix seed oil microemulsion contains 5 to 13 grams of coix seed oil, 20 to 30 grams of composite emulsifiers, 1 to 2 grams of emulsifier aids, 0 to 10 grams of dispersants and the balance of water. The microemulsion is prepared by uniform magnetic stirring at 40 DEG C. The preparation method for the coix seed oil microemulsion has the advantages of small addition amount of the emulsifiers, simple process, high oil load, high bioavailability and the like.

Description

technical field [0001] The invention relates to a formula and a preparation process of a coix seed oil microemulsion, and belongs to the technical field of traditional Chinese medicine microemulsion preparation. Background technique [0002] Coix seed is the dry mature seed kernel of grass Coix lacrymajoib L.var.mayuen (Roman.) Stapf. Coix seed contains protein, fat, starch, a small amount of vitamin B, coixin, coixin, triterpenoids and rich mineral elements necessary for the human body. Its nutritional value is the first among grasses. Coix seed oil has the functions of enhancing the immune function of the body, providing energy nutrition, treating cardiovascular system diseases, and inhibiting malignant tumors. [0003] Coix seed oil microemulsion preparation has the advantages of reducing the decomposition of active ingredients in the body, promoting the absorption of active ingredients, and improving bioavailability. Chinese patent CN101530575A "A nano-oral preparation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/107A61P9/00A61P35/00A61P37/04
Inventor 易醒肖小年熊华刘媛洁
Owner NANCHANG UNIV
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