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Compound traditional Chinese medicine for treating slow arrhythmia and preparation method thereof

A technology of arrhythmia and compound Chinese medicine, applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, can solve problems such as no therapeutic drugs, achieve a reasonable and advanced extraction process, and increase stability.

Inactive Publication Date: 2010-11-10
ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no clear medical treatment that can cure chronic arrhythmia, and there is no ideal drug for treatment except for the installation of a pacemaker.

Method used

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  • Compound traditional Chinese medicine for treating slow arrhythmia and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take the Chinese herbal medicine according to the following ratio:

[0031] Astragalus 30g Guizhi 15g Danfu Tablet 15g Salvia miltiorrhiza 30g Chuanxiong 9g Psoralen 12g Roasted licorice 6g

[0032] Dried ginger 6g Asarum 2g

[0033] 1) Weigh 15g of cassia twig, 9g of Chuanxiong, 6g of dried ginger and 2g of asarum according to the ratio of medicinal materials, put them in a round bottom flask, add 256g of water, and soak for 1 hour;

[0034] 2) Connect the upper mouth of the round-bottomed flask in step 1) to a volatile oil extractor, use steam distillation to extract for 7 hours, filter the extract in the round-bottomed flask, keep the filter residue, and concentrate the filtrate to a concentrated medicinal solution with a relative density of 1.0 for subsequent use;

[0035] 3) Separating, collecting and weighing the volatile oil in the volatile oil extractor, placing it in a stoppered test tube, adding 2 times the weight of the volatile oil in absolute ethanol to fu...

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Abstract

The invention discloses a compound traditional Chinese medicine for treating slow arrhythmia, which is prepared from the following Chinese medicinal materials by weight: 24 to 36 grams of astragalus, 12 to 18 grams of cassia twig, 12 to 18 grams of desalted aconite accessory root, 24 to 36 grams of root of red-rooted salvia, 7 to 11 grams of szechuan lovage rhizome, 9 to 15 grams of malaytea scurfpea fruit, 4 to 8 grams honey-fried liquorice root, 4 to 8 grams of dried ginger and 1 to 3 grams of manchurian wildginger. A preparation method comprises the following steps of: extracting volatile oil in the cassia twig, the szechuan lovage rhizome, the dried ginger and the manchurian wildginger by using a steam distillation method, and performing the inclusion of beta-cyclodextrin to obtain an volatile oil inclusion compound; decocting the inclusion compound independently in water; decocting the remaining medicinal materials in the water for extracting, and depositing the extracted medicinal materials by using alcohol for refining; and merging extract, performing spray drying, adding the inclusion compound into dry powder, palletizing and packaging. The preparation method has the advantages of extracting volatile components in the compound traditional Chinese medicine effectively, retaining active ingredients of the compound traditional Chinese medicine farthest, improving the stability of the volatile components and greatly improving the solubility of the volatile components simultaneously, facilitating the implementation of a sequent preparation process, and improving the stability of preparations and the effect of clinical application, along with reasonability and simplicity.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine for treating chronic arrhythmia and a preparation method thereof. It belongs to the technical field of traditional Chinese medicine. Background technique [0002] At present, my country is about to enter an aging society, and the health problems of the elderly will become one of the important factors affecting the stable and rapid development of the family and society. In order to protect the health of the elderly and improve the quality of life, researching the diseases of the elderly and developing various preventive and therapeutic drugs are important topics faced by important scientific researchers. [0003] Bradyarrhythmia is a disease of abnormal heart beat, and it is a common geriatric disease. Long-term bradycardia is one of the common TCM symptoms. . Sick sinus is a chronic progressive disease of the sinus node, which occurs in middle-aged and elderly people. However, the eti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/06
Inventor 李亚平寿旦俞忠明章建民
Owner ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE
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