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Pharmaceutical composition for treating dog dermatomycosis, and preparation method thereof

A technology of dermatophytosis and composition, which is applied in the field of drugs for treating canine dermatophytosis, can solve the problems of large toxic and side effects and low curative effect, and achieve the effect of small toxic and side effects, low price and remarkable curative effect

Inactive Publication Date: 2012-05-09
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is to overcome the defects such as low curative effect and large toxic and side effects of existing medicines for treating canine fungal infection skin diseases, and to provide a new medicine for treating canine fungal infection skin diseases. Dermatology has significant curative effect, and good safety, less toxic and side effects

Method used

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  • Pharmaceutical composition for treating dog dermatomycosis, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation of embodiment 1 spray

[0023] Weigh each component by weight as follows:

[0024] 1. Matrine 0.01kg

[0025] 2. Bifonazole 0.1kg

[0026] 3. Dimethylsulfoxide 2.75kg

[0027] 4. Glycerin 3kg

[0028] 5.95% ethanol 3.775kg

[0029] Dissolve matrine and bifonazole in dimethyl sulfoxide first, then add glycerin and 95% ethanol, mix the above components evenly, add water to 10000ml, stir to fully dissolve each component in water, fill to In plastic jars, 100ml each, keep away from light.

Embodiment 2

[0030] The preparation of embodiment 2 spray

[0031] Weigh each component by weight as follows:

[0032] 1. Matrine 0.005kg

[0033] 2. Bifonazole 0.08kg

[0034] 3. Dimethylsulfoxide 2.0kg

[0035] 4. Glycerin 1kg

[0036] 5.95% ethanol 3.0kg

[0037] Dissolve matrine and bifonazole in dimethyl sulfoxide first, then add glycerin and 95% ethanol, mix the above components evenly, add water to 10000ml, stir to fully dissolve each component in water, fill to In plastic jars, 100ml each, keep away from light.

Embodiment 3

[0038] The preparation of embodiment 3 spray

[0039] Weigh each component by weight as follows:

[0040] 1. Matrine 0.03kg

[0041] 2. Bifonazole 0.15kg

[0042] 3. Dimethylsulfoxide 3.5kg

[0043] 4. Glycerin 5kg

[0044] 5.85% ethanol 4.5kg

[0045] Dissolve matrine and bifonazole in dimethyl sulfoxide first, then add glycerin and 85% ethanol, mix the above components evenly, add water to 10000ml, stir, so that each component is fully dissolved in water, and fill to the plastic Cans, 100ml per can, keep away from light.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating dog dermatomycosis, and a preparation method thereof. The pharmaceutical composition comprises the components of matrine, bifonazole, dimethyl sulfoxide, glycerol and ethanol. Clinical observation experiment shows that the pharmaceutical composition has remarkable treatment effect for the dog skin diseases caused by various funguses, and has the whole treatment effect superior to other similar drugs. The pharmaceutical composition contains no hormone, has no side effect such as tolerance and the like which are common in other drugs, has the advantages of remarkable treatment effect, low toxic side effect, natural crude drugs, lower price and the like, and can be effectively used for treating dog dermatomycosis.

Description

technical field [0001] The invention relates to a medicament for treating animal skin diseases, in particular to a medicament for treating canine dermatophytosis and a preparation method thereof, and belongs to the field of medicaments for treating canine dermatophytosis. Background technique [0002] Canine dermatosis can take place throughout the year, more often in summer and autumn, less in cold winter. All diseases that can cause dog skin itching, hair loss, crusting and abnormal skin changes are collectively referred to as skin diseases. There are many factors that cause dog skin diseases, including infectious factors (viral, bacterial, suppurative, fungi, parasites, etc.) and non-infectious factors (hormones, nutrition, allergies, heredity). Although skin diseases generally do not cause the death of dogs, they have a long treatment cycle, are prone to relapse, and some can infect humans, so they should be taken seriously. [0003] Canine skin diseases can be roughly...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4375A61K31/4174A61P31/10A61P17/00
Inventor 李术由天姿徐世文贾琳琳付瑶李铭
Owner NORTHEAST AGRICULTURAL UNIVERSITY