Method for preparing 2,2-diisopropylpropionitrile

Abstract

The invention relates to a method for preparing 2,2-diisopropylpropionitrile, which comprises the following steps: preparing isopropyl sulfonic acid ester from isopropanol and sulfonyl chloride, and preparing the 2,2-diisopropylpropionitrile from the isopropyl sulfonic acid ester and propionitrile under the catalytic action of strong base. The invention solves the problems of high cost of raw materials, tough production conditions and long production cycle, and the problem that the method is not beneficial to industrial operation in the prior art. Thus, the method for preparing 2,2-diisopropylpropionitrile has the advantages of low production cost, simple production process and short production cycle, and is beneficial to industrial production.

Description

A method for preparing 2,2-diisopropylpropionitrile technical field The invention relates to a method for preparing 2,2-diisopropylpropionitrile. Specifically, it is a method for preparing 2,2-diisopropylpropionitrile with low production cost, simple production process, short production period and favorable industrial production. Background technique 2,2-Diisopropylpropionitrile is the key intermediate of the new cooling agent WS-23, the full name of WS-23 is N,2,3-trimethyl-2-(1-methyl Ethyl) butyramide or N,2,3-trimethyl-2-isopropyl butanamide is widely used in food, beverage, candy, cosmetics, tobacco products, medicine, etc. The preparation method of 2,2-diisopropylpropionitrile mainly contains two kinds at present, method one: the people such as Simeon adopts in the system of lithium diisopropylamide / tetrahydrofuran, methyl bromide and 2,2-diisopropyl condensed acetonitrile to synthesize 2,2-diisopropylpropionitrile; or in the presence of sodium amide / liquid ammoni...

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Problems solved by technology

For this reason, the technical problem to be solved by the present invention lies in the problems of expensive raw materials, harsh production conditions, long production cycle and unfavorable industrial operation in the prior art, thereby providing a kind of low production cost, simple production process and long production cycle. The method for preparing 2,2-diisopropylpropionitrile that is short and beneficial to industrialized production

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