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Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof

An antidepressant and composition technology, applied to the antidepressant traditional Chinese medicine composition and the field of preparation and application thereof, can solve the problems of less medicinal taste and the like, and achieve the effects of less medicinal taste, easy availability of resources and broad application prospects

Active Publication Date: 2011-09-28
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no reports about the traditional Chinese medicine composition and its preparation method and application of the antidepressant with less medicinal taste and significant curative effect

Method used

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  • Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 Preparation of antidepressant traditional Chinese medicine composition (1)

[0022] Hemerocallis flower 70%, Curcuma 15%, Raw Paeoniae Alba 15%.

[0023] Take 10 parts of raw medicinal materials of daylily flowers, turmeric, and raw white peony, add 8-10 times the amount of water, decoct for 1-2 hours, filter after cooling slightly, add 6-8 times the amount of water to decoct the dregs , then cool and filter, combine the two filtrates, heat and concentrate under vacuum to a concentrated solution containing 1-2 grams of crude drug per milliliter, and gradually add 85-95% ethanol by gradient increasing method, so that the alcohol content of the system reaches 60-80% , refrigerated, filtered, and the filtrate recovered ethanol to a relative density of 1.05-1.40, filtered to obtain the extract. Take the above extract, add pharmaceutical excipients, and make various preparations according to conventional methods.

Embodiment 2

[0024] Example 2 Preparation of antidepressant traditional Chinese medicine composition (two)

[0025] Hemerocallis 40%, Curcuma 40%, Raw Paeoniae Alba 20%.

[0026] Take 10 parts of raw medicinal materials of daylily flowers, turmeric, and raw white peony, add 8-10 times the amount of water, decoct for 1-2 hours, filter after cooling slightly, add 6-8 times the amount of water to decoct the dregs , then cool and filter, combine the two filtrates, heat and concentrate under vacuum to a concentrated solution containing 1-2 grams of crude drug per milliliter, and gradually add 85-95% ethanol by gradient increasing method, so that the alcohol content of the system reaches 60-80% , refrigerated, filtered, and the filtrate recovered ethanol to a relative density of 1.05-1.40, filtered to obtain the extract. Take the above extract, add pharmaceutical excipients, and make various preparations according to conventional methods.

Embodiment 3

[0027] Example 3 Preparation of antidepressant traditional Chinese medicine composition (3)

[0028] Hemerocallis flower 50%, Curcuma 20%, Raw Paeoniae Alba 30%.

[0029] Take 10 parts of raw medicinal materials of daylily flowers, turmeric, and raw white peony, add 8-10 times the amount of water, decoct for 1-2 hours, filter after cooling slightly, add 6-8 times the amount of water to decoct the dregs , then cool and filter, combine the two filtrates, heat and concentrate under vacuum to a concentrated solution containing 1-2 grams of crude drug per milliliter, and gradually add 85-95% ethanol by gradient increasing method, so that the alcohol content of the system reaches 60-80% , refrigerated, filtered, and the filtrate recovered ethanol to a relative density of 1.05-1.40, filtered to obtain the extract. Take the above extract, add pharmaceutical excipients, and make various preparations according to conventional methods.

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Abstract

The invention relates to a traditional Chinese medicine composition for resisting depression, which is characterized by being prepared from the following raw medicines in percentage by weight: 40-70% of hemerocallis fulva, 15-40% of radix curcumae and 15-40% of raw white peony root. The invention also provides a preparation method as well as application of the traditional Chinese medicine composition for resisting depression. The invention has the advantages that the traditional Chinese medicine composition provided by the invention is prepared by screening layer by layer and simplifying gradually on the basis of taking traditional Chinese medicine theories and clinical researches as guidance, pure natural traditional Chinese medicine raw materials are selected, and all raw materials are proportioned to accord with the 'monarch, minister, assistant and guide' principle in the traditional Chinese medicine. The pharmacological experiment proves that the traditional Chinese medicine composition has obvious functions of calming the liver, relieving depression, tranquilizing mind and soothing the nerves, has the advantages of obvious treatment effect, small side effect, easy avalaibility of resources, few medicines and low price, is simple and convenient to prepare, is suitable for being taken for a long time, is a safe and effective medicament for treating depression and anxiety neurosis, and has wide application prospects.

Description

technical field [0001] The invention relates to an antidepressant traditional Chinese medicine composition and its preparation method and application, in particular, it is a Chinese patent medicine prepared from Chinese herbal medicines as raw materials. Background technique [0002] Depression is the main type of affective disorder. It is a syndrome characterized by significant and persistent depression as the main clinical feature. attempted suicide etc. At present, most of the drugs used to treat depression are chemical drugs with a wide variety, but Western drugs are often highly dependent, have large side effects, take a long time, and are prone to withdrawal symptoms and even series of reactions. Some even need to take drugs for life, which seriously damages the liver and kidneys. Function, forming a vicious circle, improper use of treatment not only can not treat depression, but may exacerbate the condition or transform into other mental diseases. [0003] Depressio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/24A61P25/22
Inventor 王翘楚许红王国华徐建张雯静严晓丽王惠茹许良张晓峰吴樱
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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