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Subing (quick effect heart rescue) spraying agent and its preparation method

A spray and quick-acting technology, which is applied in the field of compound traditional Chinese medicine Subing spray and its preparation, can solve the problems that there is no Subing formula, its preparation process and clinical application reports, etc., so as to avoid a large amount of volatilization, the preparation method is simple, and it is easy to apply foreground effect

Inactive Publication Date: 2012-03-14
王登之
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After retrieval, there is no report on the formulation, preparation process and clinical application of Subing (Suxiao Jiuxin) Spray

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 5 grams of storax sesame oil, 10 grams of borneol, 15 milliliters of absolute ethanol, 40065 milliliters of polyethylene glycol, and water to 100 milliliters. Weigh borneol and styrax oil according to the above ratio, dissolve in absolute ethanol and polyethylene glycol 400, stir evenly, add water to a sufficient amount, stir evenly with a milk homogenizer, quantitatively put into a spray container, and obtain a finished product.

[0027] Spray directly into the mouth when using, 1-3 sprays at a time.

Embodiment 2

[0029] 5 grams of styrofoam oil, 10 grams of borneol, 10 milliliters of propylene glycol, 28 milliliters of polysorbate 80 (Tween 80), and 20% ethanol to 100 milliliters. Weigh borneol and styrax oil according to the above ratio and add them to polysorbate 80 (Tween 80), stir evenly, add 20% ethanol to a sufficient amount, stir evenly with a homogenizer, and quantitatively put them into an aerosol container to obtain a finished product .

[0030] Spray directly into the mouth when using, 1-3 sprays at a time.

Embodiment 3

[0032] 1 gram of styrax oil, 2 grams of borneol, 5 grams of poloxamer 188, and 35% ethanol to 100 ml. Weigh borneol, styrax oil and poloxamer according to the above ratio and dissolve in 35% ethanol, stir evenly with a homogenizer, quantitatively put into a spray container to obtain a finished product.

[0033] Spray directly into the mouth when using, 1-5 sprays at a time.

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PUM

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Abstract

The invention provides a novel traditional Chinese medicinal compound Subing (quick effect heart rescue) spraying agent and its preparation method and belongs to the field of biomedicine, wherein the Subing (quick effect heart rescue) spraying agent has a good curative effect of resisting coronary angina pectoris. The problem of dissolving borneol with levant storax oil is solved by a new technology and a new method. The prescription is composed of styrax, borneol, a solubiliser, an absorption enhancer and a solvent. By the simple new technology of dissolution, homogenization and the like, borneol which is completely insoluble in water and levant storax oil which is not miscible with water phase are dissolved together in an oral water-soluble base so as to obtain an oral solution which is uniform and transparent without layers and suspension. The spraying agent or aerosol prepared in the invention can be quantitatively and directly sprayed into mouth or sprayed under tongue or directly sprayed into nasal cavity. In comparison with a solid preparation, the spraying agent prepared by styrax and borneol for oral administration has advantages of fast absorption and rapid effect, can perform a curative effect better and faster, is applicable to be taken by patients with angina pectoris during the acute phase. By the adoption of the preparation method provided by the invention, the effect onset time is greatly shortened within 60 seconds. The preparation method provides a good therapeutic novel medicine for currently high frequency and high occurrence of heart disease in our country.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine Su Bing (quick-acting heart-saving) spray for preventing and treating angina pectoris and the like and a preparation method thereof, belonging to the field of biomedicine. Background technique [0002] Styrax is the balsam resin exuded from the trunk of the storax tree Liquidambar orientalis Mill. of Hamamelidaceae, which is processed and refined. Its properties are semi-fluid thick liquid, brownish yellow or dark brown, translucent and viscous. The air is fragrant. Functions and indications are to resuscitate, eliminate filth, and relieve pain. For apoplectic phlegm, fainting suddenly, chest and abdomen cold pain, convulsions, epilepsy, febrile syndrome. Borneolum is a resin processed product of the evergreen arbor plant Diobalanops aromaticops aromati-ca Gaertn.f., or a product synthesized by chemical methods using camphor, turpentine, etc., or a perennial herb of the Compositae fami...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/12A61P9/10A61K31/045
Inventor 王登之侯鹏周艳
Owner 王登之
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