The invention discloses an
ambroxol hydrochloride osmotic pump controlled-release tablet, which belongs to the field of preparation of
ambroxol hydrochloride osmotic pump controlled-release tablets. The
ambroxol hydrochloride osmotic pump controlled-release tablet of the present invention comprises a tablet core composed of a
drug-containing layer and a booster layer, the tablet core is covered with a semipermeable film coat, and one or more small
drug release holes are arranged on the surface of the semipermeable film coat , pack
moisture-proof clothing; Described
drug-containing layer is made up of
ambroxol hydrochloride, suspending agent, penetrating agent,
osmotic pressure active substance, binding agent, colorant and
lubricant; Described booster layer is made up of penetrating agent, It is composed of
polymer swelling material,
osmotic pressure active substance, coloring agent,
adhesive and
lubricant; the semipermeable
film coating is composed of
film material,
plasticizer, porogen and
solvent. The
ambroxol hydrochloride osmotic pump controlled-release tablet of the present invention has the advantages of convenient administration, long-lasting effect, release at an approximately
constant rate for 0-12 hours, maintains stable
blood drug concentration, reduces toxic and side effects, reduces the number of times of taking
medicine and has a suitable tablet Weight, enhance
patient compliance and other advantages.