Traditional Chinese medicine composition containing folium artemisiae argyi for treating primary hyperuricemia

A technology for hyperuricemia and composition, which is applied in the field of traditional Chinese medicine composition for treating primary hyperuricemia, can solve the problems of single dosage forms and limited applicability, and achieve simple preparation process and high applicability Broadening and reducing the effect of serum uric acid concentration

Inactive Publication Date: 2016-07-13
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There are many invention patents for the treatment of primary hyperuricemia disclosed at present, but they are basically western medicines. For example: Chinese invention patent application: 200810054282.8 discloses a pharmaceutical composition for the treatment of primary hyperuricemia. The pharmaceutical composition includes febuxostat or other derivatives, probenecid and a pharmaceutically acceptable pharmaceutical carrier; febuxostat and probenecid, which play the main role in the pharmaceutical composition, have certain liver and kidney functions. Toxicity, and the dosage form is relatively simple, so the applicability is not wide

Method used

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  • Traditional Chinese medicine composition containing folium artemisiae argyi for treating primary hyperuricemia
  • Traditional Chinese medicine composition containing folium artemisiae argyi for treating primary hyperuricemia
  • Traditional Chinese medicine composition containing folium artemisiae argyi for treating primary hyperuricemia

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The Chinese medicinal composition of Example 1 of the present invention comprises the following Chinese medicinal materials in parts by weight:

[0045]

[0046] The preparation method is as follows:

[0047] (1) Remove impurities from Artemisia argyi, Fructus Fructus L., Radix Glycyrrhizae, Radix Curcumae, Ophiopogon japonicus, Radix Glycyrrhizae, wash, dry, and pulverize into coarse powder;

[0048] (2) removing the surface layer of plantain, washing, drying, and pulverizing into coarse powder;

[0049] (3) After mixing the coarse powder prepared in the above step (1) and step (2), add 6 times the amount of water to soak for 1 hour, decoct for 3 hours; filter, add 3 times the amount of water to the filter residue, and decoct for 2 hours; Filter, add 1 times the amount of water to the filter residue, decoct for 1 hour, filter, combine the three filtrates, concentrate the filtrate to a concentrated solution with a relative density of 1.15 at 55°C, and set aside;

[0...

Embodiment 2

[0054] The Chinese medicine composition of embodiment 2 of the present invention comprises the Chinese medicinal material of following parts by weight:

[0055]

[0056] The preparation method is as follows:

[0057] (1) Remove impurities from Artemisia argyi, Fructus Fructus L., Radix Glycyrrhizae, Radix Curcumae, Ophiopogon japonicus, Radix Glycyrrhizae, wash, dry, and pulverize into coarse powder;

[0058] (2) removing the surface layer of plantain, washing, drying, and pulverizing into coarse powder;

[0059] (3) Mix the coarse powder prepared in the above step (1) and step (2) evenly, add 12 times the amount of water to soak for 3 hours, decoct for 5 hours; filter, add 6 times the amount of water to the filter residue, and decoct for 4 hours; Filter, add 3 times the amount of water to the filter residue, decoct for 2 hours, filter, combine the three filtrates, concentrate the filtrate to a concentrated solution with a relative density of 1.20 at 60°C, and set aside; ...

Embodiment 3

[0064] The Chinese medicine composition of embodiment 3 of the present invention comprises the Chinese medicinal material of following parts by weight:

[0065]

[0066] The preparation method is as follows:

[0067] (1) Remove impurities from Artemisia argyi, Fructus Fructus L., Radix Glycyrrhizae, Radix Curcumae, Ophiopogon japonicus, Radix Glycyrrhizae, wash, dry, and pulverize into coarse powder;

[0068] (2) removing the surface layer of plantain, washing, drying, and pulverizing into coarse powder;

[0069] (3) Mix the coarse powder prepared in the above step (1) and step (2) evenly, add 12 times the amount of water for 3 hours, decoct for 5 hours; filter, add 6 times the amount of water to the filter residue, and decoct for 4 hours; Filter, add 3 times the amount of water to the filter residue, decoct for 2 hours, filter, combine the three filtrates, concentrate the filtrate to a concentrated solution with a relative density of 1.20 at 60°C, and set aside;

[0070]...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition containing folium artemisiae argyi for treating primary hyperuricemia. The traditional Chinese medicine composition comprises the following preparation raw materials: folium artemisiae argyi, bark of ash, lycopodium clavatum, radix curcumae, radix ophiopogonis, plantain herb, trichosanthes palmata, ligusticum wallichii, radix angelicae, frangrant daphne flowers, rhizoma zingiberis and liquorice. The traditional Chinese medicine composition abides by the prescription principles of monarch, minister, assistant and guide, is proper in medication, rigorous in compatibility and primary and secondary trenchant, achieves mutual gain, and is capable of dispelling wind, relieving pain, clearing away heat, removing dampness and normalizing the gallbladder function to treat jaundice. The traditional Chinese medicine composition is high in pertinence, obvious in curative effect and high in cure rate on treatment of the primary hyperuricemia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition containing mugwort leaves for treating primary hyperuricemia. Background technique [0002] With the development of society and changes in human diet and dietary structure, metabolic diseases have become major diseases that seriously affect the quality of life of our people, and the prevalence of hyperuricemia has increased most significantly. Uric acid is a weak acid with low solubility and no physiological function. It is in the form of sodium urate in the environment of normal human body fluid pH7.4, and in the form of uric acid in acidic liquid. There are two sources of uric acid in the human body, one is exogenous, mainly from the decomposition of nucleotides in foods rich in nucleoproteins In addition, it is endogenous, which comes from the synthesis of amino acids, phosphoribose and other small m...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P19/06
CPCA61K36/282A61K36/11A61K36/232A61K36/236A61K36/484A61K36/59A61K36/63A61K36/68A61K36/83A61K36/8968A61K36/9066A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 王一飞王亦梁刘秋英利奕成
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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