Aseptic powder injection used for breasts of cow with mastitis and preparation method thereof
A technology for dairy cow mastitis and sterile powder injection, which is applied in the field of drugs for the treatment of cow mastitis, can solve the problems of aggravating drug residues, reducing product output and quality, and increasing transportation costs, and achieves controllable quality and good thermal stability , the effect of convenient transportation
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Embodiment 1
[0022] Example 1 The method for preparing the aseptic powder injection preparation for nisin dairy cow udder with a titer of 1,500,000 units / g and an aqueous solution with a pH value of 3 comprises the following steps:
[0023] (1) 5 grams of vitamin C are dissolved in 1000 milliliters of distilled water, and the content of vitamin C is mixed with 0.5%, and the aqueous solution whose pH value is 3;
[0024] (2) 10 grams of nisin, with a titer of 15000 units / mg, is dissolved in the solution of step (1);
[0025] (3) Sterilize by filtration and dry to remove 90% of water.
Embodiment 2
[0026] Example 2 The method for preparing a sterile powder injection preparation for nisin dairy cow udder with a titer of 3,000,000 units / g and an aqueous solution with a pH value of 2 comprises the following steps:
[0027] (1) 50 grams of vitamin C are dissolved in 1000 milliliters of distilled water, and the vitamin C content that is mixed with is 5%, and the aqueous solution of pH value is 2;
[0028] (2) 20 grams of nisin with a titer of 15000 units / mg are dissolved in the solution of step (1);
[0029] (3) Sterilize by filtration and dry to remove 90% of water.
Embodiment 3
[0030] Example 3 The method for preparing a nisin milk cow udder sterile powder preparation with a titer of 500,000 units / g and an aqueous solution with a pH value of 3 comprises the following steps:
[0031] (1) 25 grams of vitamin C are dissolved in 5000 milliliters of distilled water to prepare an aqueous solution with a pH value of 3;
[0032] (2) 2.5 grams of nisin with a titer of 20000 units / mg are dissolved in the solution of step (1);
[0033] (3) Sterilize by filtration and dry to remove 90% of water.
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