Aseptic powder injection used for breasts of cow with mastitis and preparation method thereof

A technology for dairy cow mastitis and sterile powder injection, which is applied in the field of drugs for the treatment of cow mastitis, can solve the problems of aggravating drug residues, reducing product output and quality, and increasing transportation costs, and achieves controllable quality and good thermal stability , the effect of convenient transportation

Active Publication Date: 2009-01-07
福建大北农华有水产科技集团有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The long-term, extensive and high-dose use of antibiotics in the treatment of cow mastitis has led to a series of adverse consequences
The first is the problem of food public health: after treatment with antibiotics, there is a potential risk of drug residues in milk, which will adversely affect human health; secondly, the increase in drug-resistant strains: pathogenic bacteria develop drug resistance, making mastitis more severe It is becoming more and more difficult to cure, and veterinarians on cattle farms have to increase the dosage of antibiotics, which increases the risk of drug residues; other hazards of drug residues include inhibition of the fermentation process in dairy production, resulting in reduced product yield and quality
However, the solution has the disadvantages of inconvenient transportation, increased weight and increased transportation costs.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 The method for preparing the aseptic powder injection preparation for nisin dairy cow udder with a titer of 1,500,000 units / g and an aqueous solution with a pH value of 3 comprises the following steps:

[0023] (1) 5 grams of vitamin C are dissolved in 1000 milliliters of distilled water, and the content of vitamin C is mixed with 0.5%, and the aqueous solution whose pH value is 3;

[0024] (2) 10 grams of nisin, with a titer of 15000 units / mg, is dissolved in the solution of step (1);

[0025] (3) Sterilize by filtration and dry to remove 90% of water.

Embodiment 2

[0026] Example 2 The method for preparing a sterile powder injection preparation for nisin dairy cow udder with a titer of 3,000,000 units / g and an aqueous solution with a pH value of 2 comprises the following steps:

[0027] (1) 50 grams of vitamin C are dissolved in 1000 milliliters of distilled water, and the vitamin C content that is mixed with is 5%, and the aqueous solution of pH value is 2;

[0028] (2) 20 grams of nisin with a titer of 15000 units / mg are dissolved in the solution of step (1);

[0029] (3) Sterilize by filtration and dry to remove 90% of water.

Embodiment 3

[0030] Example 3 The method for preparing a nisin milk cow udder sterile powder preparation with a titer of 500,000 units / g and an aqueous solution with a pH value of 3 comprises the following steps:

[0031] (1) 25 grams of vitamin C are dissolved in 5000 milliliters of distilled water to prepare an aqueous solution with a pH value of 3;

[0032] (2) 2.5 grams of nisin with a titer of 20000 units / mg are dissolved in the solution of step (1);

[0033] (3) Sterilize by filtration and dry to remove 90% of water.

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Abstract

The invention provides a germ-free powder injection for treating cow mammitis and its preparing process, wherein the injection comprises lactic acid streptostacin to replace antibiotics in cow mammitis treatment, as a result, no unwanted residual to human body is formed in milk. The injection also has the advantages of controllable quality, better stability and convenience in transportation.

Description

technical field [0001] The invention relates to a medicine for treating cow mastitis, in particular to a sterile powder injection preparation for treating cow mastitis and a preparation method of the sterile powder injection preparation. Background technique [0002] Cow mastitis is one of the most common diseases that harm the dairy farming industry. About 50% of dairy cows in the world suffer from various types of mastitis. Affected cows have reduced milk production and quality. The direct economic loss caused by cow mastitis in the United States reaches 2 billion US dollars every year. About 70% of the loss caused by mastitis in dairy cows is the decline in milk production caused by recessive mastitis. In China, the annual loss caused by recessive mastitis alone is at least 135 million yuan. The main cause of mastitis in dairy cows is the infection of the mammary glands with pathogenic microorganisms. Therefore, the current treatment of the disease is based on antibio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/10A61K38/16A61K9/14A61P15/14
Inventor 莫云刘彤胡松华
Owner 福建大北农华有水产科技集团有限公司
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