Application of flavone glycoside compounds in preparing medicament for treating and preventing hepatitis

Abstract

The invention belongs to the field of pharmacy, and provides application of three flavone glycoside compounds luteolin-7-O-[alpha-L-rhamnose-(1->2)]-beta-D-glucoside (trivial name is lonicerin), apigenin-7-O-[alpha-L-rhamnose-(1->2)]-beta-D-glucoside (trivial name is rhoifolin) and luteolin-6-C-beta-D-glucose-8-C-beta-D-xyloside in preparing medicament or health-care food for preventing and treating hepatitis.

Description

technical field [0001] The invention belongs to the field of pharmacy, and specifically relates to the application of flavonoid glycosides represented by general formula I in the preparation of medicines for treating and preventing hepatitis. Background technique [0002] Hepatitis is one of the infectious diseases with high morbidity and mortality and serious harm. According to the etiology, it can be divided into viral hepatitis, autoimmune hepatitis, drug-induced hepatitis, alcoholic hepatitis and hepatitis caused by other infectious agents. Among hepatitis, viral hepatitis is the most harmful to humans, especially hepatitis B. At present, there are more than 350 million chronic hepatitis B virus carriers in the world. my country is a high-prevalence area of ​​hepatitis virus infection, and there are more than 120 million hepatitis B surface antigen carriers. Chronic hepatitis B is also easy to develop into liver cirrhosis and even liver cancer. About 500,000 people die ...

AI Technical Summary

Problems solved by technology

Formula Ⅰ

Images