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Chinese materia medica preparation for curing chronic kidney disease and preparation method of Chinese materia medica preparation

A technology for chronic kidney disease and traditional Chinese medicine preparations, applied in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as lack of traditional Chinese medicine connotations, delay the time to enter dialysis, protect residual renal function, The effect of delaying the decline of renal function

Active Publication Date: 2014-04-16
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing spleen-tonifying and kidney-reinforcing prescriptions for treating chronic kidney disease are traditional Chinese medicine prescriptions prepared by Chinese medicine practitioners to treat kidney disease patients. Most of them do not have profound Chinese medicine connotations, and have not been demonstrated and optimized many times

Method used

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  • Chinese materia medica preparation for curing chronic kidney disease and preparation method of Chinese materia medica preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine preparation for treating chronic kidney disease. The weight ratio of raw materials is as follows: 30 parts of Radix Astragali, 20 parts of Codonopsis Radix, 15 parts of Atractylodes Rhizoma Atractylodes Rhizome, 15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Polygonum multiflorum, 15 parts of Cuscuta, coix seed 20 parts, 15 parts of Danshen.

[0022] The preparation method of the above-mentioned traditional Chinese medicine preparation for treating chronic kidney disease comprises the following steps: after pulverizing each raw material respectively, mixing and adding 300 parts by weight of water, soaking for 30 minutes, decocting for 30 minutes after boiling, filtering to obtain filtrate 1 and filter residue, and pouring Add 250 parts by weight of water to the filter residue, continue to boil, then decoct for 30 minutes, filter to obtain filtrate 2, and mix filtrate 1 and filtrate 2 to obtain a traditional Chinese medicine p...

Embodiment 2

[0024] A traditional Chinese medicine preparation for treating chronic kidney disease. The weight ratio of raw materials is as follows: 28 parts of Radix Astragali, 22 parts of Codonopsis Radix, 16 parts of Atractylodes Rhizoma Atractylodes Rhizome, 14 parts of Poria cocos, 13 parts of Chinese yam, 17 parts of Polygonum multiflorum, 15 parts of Cuscuta, coix seed 20 parts, 18 parts of Danshen.

[0025] The preparation method of the above-mentioned traditional Chinese medicine preparation for treating chronic kidney disease comprises the following steps: after pulverizing each raw material respectively, mixing and adding 300 parts by weight of water, soaking for 30 minutes, decocting for 30 minutes after boiling, filtering to obtain filtrate 1 and filter residue, and pouring Add 250 parts by weight of water to the filter residue, continue to boil, then decoct for 30 minutes, filter to obtain filtrate 2, and mix filtrate 1 and filtrate 2 to obtain a traditional Chinese medicine p...

Embodiment 3

[0027] A traditional Chinese medicine preparation for treating chronic kidney disease. The weight ratio of raw materials is as follows: 33 parts of Radix Astragali, 15 parts of Codonopsis Radix, 18 parts of Atractylodes Rhizome, 17 parts of Poria cocos, 13 parts of Chinese yam, 17 parts of Polygonum multiflorum, 20 parts of Cuscuta, coix seed 15 parts, 10 parts of Danshen.

[0028] The preparation method of the above-mentioned traditional Chinese medicine preparation for treating chronic kidney disease comprises the following steps: after pulverizing each raw material respectively, mixing and adding 250 parts by weight of water, soaking for 50 minutes, decocting for 35 minutes after boiling, filtering to obtain filtrate 1 and filter residue, and feeding Add 300 parts by weight of water to the filter residue, continue to boil, then decoct for 40 minutes, filter to obtain filtrate 2, and mix filtrate 1 and filtrate 2 to obtain a traditional Chinese medicine preparation.

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Abstract

The invention discloses a Chinese materia medica preparation for curing a chronic kidney disease and a preparation method of the Chinese materia medica preparation. The Chinese materia medica preparation comprises astragalus root, pilose asiabell root, largehead atractylodes rhizome, indian buead, common yam rhizome, polygonum multiflorum, dodder, coix seed and salvia miltiorrhiza. The preparation method includes crushing raw ingredients, adding water to soak, boiling, decocting the raw ingredients, filtering, adding water into filter residues, repeating decoction, filtering, mixing two filter liquors, and obtaining the Chinese materia medica preparation. On the basis of the research of the field, the Chinese materia medica preparation is integrated with essence of the industry and is formed after being subjected to repeated demonstrations and optimizations. The Chinese materia medica preparation includes nine drugs such as the astragalus root, the pilose asiabell root, the dodder and the like, has a function of reinforcing spleen and kidney, has an obvious curative effect on the chronic kidney disease, particularly is good in effects of slowing down the decreasing of epidermal growth factor receptor (EGFR) of patients with chronic kidney disease stage 4 and the advancement of the chronic kidney disease, and is superior to an effective drug angiotensin-converting enzyme inhibitor (ACEI) internationally used.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine preparation for treating chronic kidney disease and a preparation method thereof. Background technique [0002] Definition of Chronic kidney disease (CKD): Anyone with any of the following two conditions can be diagnosed as chronic kidney disease, 1. Kidney damage (pathological, blood, urine, imaging abnormalities) ≥ 3 months; 2. , glomerular filtration rate (GFR) <60ml / min / 1.73m 2 , duration ≥3 months. Renal damage refers to abnormalities in the structure or function of the kidneys, manifested in one of the following situations: a. abnormal renal pathology; b. indicators of renal damage, including abnormal blood and urine components or abnormal renal imaging examinations. Chronic kidney disease (CKD) is divided into 5 stages according to the glomerular filtration rate. Among them, the fourth stage of chronic kidney disease (CKD stage...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P13/12
Inventor 刘旭生毛炜杨霓芝邹川黎创张蕾吴一帆卢富华林启展王立新包崑赵代鑫高燕翔梁晖徐鹏彭钰侯海晶左琪黄璟马红岩许苑苏镜旭马伟忠蔡寸苏卓伟杨敏林俊杰林书洲邓丽丽刘惠
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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