33 results about "Media otitis" patented technology

Disclosed herein are systems and methods for classifying a tympanic membrane by using a classifier. The classifier is a machine learning algorithm. A method for classifying a tympanic membrane includes steps of: receiving, from an interrogation system, one or more datasets relating to the tympanic membrane; determining a set of parameters from the one or more datasets, wherein at least one parameter of the set of parameters is related to a dynamic property or a static position of the tympanic membrane; and outputting a classification of the tympanic membrane based on a classifier model derived from the set of parameters. The classification comprises one or more of a state, a condition, or a mobility metric of the tympanic membrane.

The embodiment of the invention provides a clinical intervention decision-making method and device, electronic equipment and a storage medium, and belongs to the technical field of artificial intelligence. The method comprises the steps that secretory otitis media clinical data of a to-be-evaluated user are acquired, and the secretory otitis media clinical data comprise multiple etiological clinical features; obtaining a target secretory otitis media disease probability prediction model; on the basis of a target secretory otitis media disease probability prediction model, performing feature evaluation on the clinical features of the multiple etiologies to obtain multiple user feature scores; based on the target secretory otitis media disease probability prediction model and the plurality of user feature scores, performing disease probability prediction on the to-be-evaluated user to obtain user disease prediction data; and based on the user disease prediction data, performing clinical intervention decision on the to-be-evaluated user. According to the application, the secretory otitis media can be effectively prevented, the accuracy of clinical intervention decisions can be improved, and in addition, the treatment effect of the secretory otitis media can be effectively evaluated.

To provide an ultrasound transducer and a method.SOLUTION: An ultrasound transducer may include: a plurality of capacitive ultrasound transducer elements; and a base having a maximum dimension sized and shaped to be disposed within an external ear canal, the plurality of capacitive ultrasound transducers being mounted on the base. Each capacitive ultrasound transducer element and the ultrasound transducer are specifically constructed to achieve select desired performance characteristics. The ultrasound transducer may have an angular beam spread through a gaseous medium of greater than 15 degrees and an attenuation loss through the gaseous medium of greater than 10 dB measured at a distance 12.5 mm to 25 mm along a primary transmission axis of the ultrasound transducer. The ultrasound transducer may be particularly useful for characterizing fluid behind an ear drum to diagnose otitis media.SELECTED DRAWING: Figure 6A

This invention discloses a wearable ultrasound delivery device for treating otitis media, comprising a wearable main body with a flexible structure adapted to the shape of the patient's ear canal, and a through-hole central channel; an ultrasound drug delivery device, detachably disposed within the central channel, comprising a drug carrier for carrying the therapeutic drug to be delivered, an ultrasound transducer assembly for providing an ultrasound-guided drug delivery mode, and a handheld controller for adjusting the millimeter-level displacement of the drug carrier into the middle ear cavity; wherein, the ultrasound transducer assembly comprises a flexible substrate and multiple piezoelectric transducer units integrated on the flexible substrate, the multiple piezoelectric transducer units constituting a phased array transducer array. This device solves the technical problems of inaccurate drug delivery, low drug delivery efficiency, inability to adapt to the ear canal structure, and complex operation in the prior art.

A system for assessing AOM includes a computing device having a processor apparatus, wherein the processor apparatus implements a diagnostic classifier component that comprises a. trained neural network, the processor apparatus being structured and configured to receive tympanic membrane image data representing one or more images of a tympanic membrane of the patient, provide the tympanic membrane image data to the diagnostic classifier component, and process the tympanic membrane image data in the diagnostic classifier component to determine: (i) a plurality of tympanic membrane features from the tympanic membrane image data, (ii) a diagnosis of whether the patient has AOM based on the plurality of tympanic membrane features, (iii) a. confidence in the diagnosis, and (iv) an identification one or more of the tympanic membrane features determined to be predominant contributing features that led to the diagnosis.

The invention discloses an ear drop for treating otitis media and a preparation method thereof in the technical field of otitis media treatment, and the ear drop comprises the following raw materials in parts by weight: 10-60 parts of coptis chinensis, 5-20 parts of boric acid, 6-20 parts of borneol and 600-1300 parts of boiling water. According to the invention, coptis chinensis has a good treatment effect on inflammation and infection caused by otitis media, boric acid has astringency and antibacterial effects and can effectively reduce auditory meatus secretions and promote inflammation regression, and borneol can relieve pain and discomfort caused by otitis media; and by using boiling water, effective components of the medicinal materials are fully extracted in the preparation process, and meanwhile, the concentration and viscosity of the ear drops are adjusted, so that the ear drops are more suitable for the auditory meatus environment, the irritation of the ear drops is reduced, and meanwhile, the volatilization time of the ear drops in the ears of a patient is shortened.

The invention is related to 26-valent immunogenic compositions comprising 26 different S. pneumoniae polysaccharide carrier protein conjugates, wherein each of the conjugates comprises a polysaccharide from an S. pneumoniae serotype conjugated to a carrier protein, wherein the serotypes of S. pneumoniae are as defined herein. The 26-valent immunogenic compositions are useful for providing protection against S. pneumoniae infection and / or pneumococcal diseases caused by S. pneumoniae including pneumococcal pneumoniae, invasive pneumococcal disease and acute otitis media.

The present invention relates to a middle ear inflammation treatment device. Disclosed is a middle ear inflammation treatment device installed with a ventilation tube, the device comprising: a handle; a cutting sheath connected to the handle and having a tubular shape with an inner diameter greater than an outer diameter of the ventilation tube, and wherein the ventilation tube is inserted into the cutting sheath; and a suction tube formed to be relatively movable to the cutting sheath in a length direction of the cutting sheath within the cutting sheath, wherein the suction tube has a tubular shape to suck and remove exudate in a middle ear through the suction tube; and a moving tool located outside the handle and relatively moving the suction tube to the cutting sheath.

The invention discloses an imbedding ventilation pipe device for treating otitis media. The embedded ventilation pipe device for treating otitis media comprises a shell, the shell is in a hollow pipe shape, a guide part is arranged in the shell, the guide part is in a hollow pipe shape, a prefabricated part is arranged at the first end of the guide part, the prefabricated part is arranged at the first end in the shell, a ventilation pipe is arranged in the prefabricated part, and the ventilation pipe is arranged in the shell. And the second end part of the prefabricated part abuts against the first end part of the guide part. The defects of an existing surgical instrument are overcome to a certain degree, the surgical instrument is integrated, the surgical success probability is improved, and the device is better suitable for clinical use, convenient to operate, capable of shortening the surgical time and suitable for minimally invasive surgery.

The invention relates to an intelligent otitis media regulation and control method and device. The method comprises the steps that a negative electrode needle and a positive electrode needle of otitis media regulation and control equipment are connected to an intelligent regulation and control interface module; the negative electrode needle is guided by an endoscope to enter the nasal cavity of the subject; an endoscopic image is analyzed through an MSFFN positioning algorithm and a DAN model of the intelligent regulation and control interface module, preliminary image recognition is performed through the MSFFN positioning algorithm to capture multi-scale features, and treatment positions of a negative electrode needle and a positive electrode needle are learned through the DAN model; the negative electrode needle and the positive electrode needle are controlled by the intelligent treatment control interface module to be inserted into a predetermined treatment position learned by the DAN model after being in place; connecting the positive electrode needle to otitis media regulation and control equipment; and the electrode needle is positioned and adjusted through an ARNN treatment control model of the intelligent treatment control interface module. The electrode needle is intelligently controlled and adjusted through the intelligent treatment control interface module and the ARNN treatment control model, and treatment individuation and effectiveness are improved.

The invention discloses a suction device for treating otitis media of children, and belongs to the technical field of treatment of otitis media of children. The suction device is provided with a fixing spring, a connecting sleeve, a suction catheter, a fixing needle sleeve and a clamping sleeve, and after a fixing clamping block on the inner wall of the clamping sleeve corresponds to an arc-shaped clamping groove in position, the fixing needle sleeve is inserted into the arc-shaped clamping groove; a connecting sleeve is loosened, a first moving block is jacked up to reset in a strip-shaped mounting groove under the springback effect of a fixed spring, the connecting sleeve is driven to move from the surface of the mounting sleeve to the surface of a clamping sleeve, and meanwhile, the connecting sleeve extrudes the clamping sleeve, so that the clamping sleeve is clamped on the surface of a fixed needle sleeve until a fixed clamping block is clamped into an annular clamping groove; meanwhile, a connecting sleeve is tightly attached to a limiting stop block, so that the inner wall of the connecting sleeve extrudes a second rubber clamping ring, the connecting sleeve is clamped and fixed to the surface of a clamping clamping sleeve, and it is guaranteed that when the suction needle head stretches into the auditory meatus of the child for suction treatment, the fixing needle sleeve cannot fall off from the surface of the suction catheter randomly due to struggling of the child.

The invention discloses a chronic otitis media CT report automatic generation system based on a visual-language large model, and belongs to the technical field of radiation medicine. The system comprises a data acquisition and processing module for acquiring image data and text data and preprocessing the data; the vision-language large model training module is used for inputting the preprocessed data into a vision-language large model for training and adjusting and optimizing model parameters; and the report generation interaction module is used for generating a structured report by utilizing the trained vision-language large model. According to the system, the visual-language large model is applied to the field of CT report generation and typing diagnosis of chronic otitis media for the first time, the technical blank in the field is filled, and a new path is developed for intelligent diagnosis of chronic otitis media.

The embodiment of the application discloses an otological image intelligent identification method based on a multi-modal artificial intelligence, and comprises the following steps: acquiring an otological image and clinical text information of a patient; fusing the otological image and the clinical text information to obtain multi-modal features; and identifying the multi-modal clinical text information features by using a multi-model integrated architecture to automatically determine the tympanic membrane state of the patient, wherein the tympanic membrane state comprises a normal tympanic membrane, a perforation, an inward protrusion, an effusion, a suppurative otitis media, calcification and otosclerosis. The embodiment realizes automatic intelligent identification of the tympanic membrane state.

An ultrasound signal processor uses an excitation generator to cause displacement of a tympanic membrane while a series of ultrasound pulses are applied to the tympanic membrane. Phase differences between a transmitted signal and received signal are examined to determine the movement of the tympanic membrane in response to the applied excitation. An examination of the phase response of the tympanic membrane provides a determination as to whether the fluid type behind the tympanic membrane is one of: no fluid, serum fluid, or purulent fluid.

An ultrasonic transducer can include a plurality of capacitive ultrasonic transducer elements and a base having a maximum dimension sized and shaped to be disposed within an external ear canal, wherein the plurality of capacitive ultrasonic transducer elements are mounted on the base. Each capacitive ultrasonic transducer element and the ultrasonic transducer are specifically constructed to achieve selected desired performance characteristics. The ultrasonic transducer can have an angular beam that propagates through a gaseous medium that is greater than 15 degrees and an attenuation loss through the gaseous medium that is greater than 10 dB measured at a distance of 12.5 mm to 25 mm along a primary transmission axis of the ultrasonic transducer. The ultrasonic transducer can be particularly useful for characterizing fluid behind a tympanic membrane to diagnose otitis media.

Provided is an otitis media treatment instrument and, more particularly, to an otitis media treatment instrument having a ventilation tube installed thereon, the otitis media treatment instrument including: a cutting sheath which is configured in a tube shape, and which has an inner diameter larger than the outer diameter of the ventilation tube; and a suction pipe formed to be able to move relative to the cutting sheath inside the cutting sheath along the longitudinal direction of the cutting sheath, the suction pipe having, on the front end portion thereof, an insertion portion having an outer diameter smaller than the inner diameter of the ventilation tube and having a fixing portion which extends toward the front end of the insertion portion, and which has an outer diameter larger than the inner diameter of the ventilation tube.

An ultrasound transducer may include: a plurality of capacitive ultrasound transducer elements; and a base having a largest dimension sized and shaped to be disposed with an external ear canal, wherein the plurality of capacitive ultrasound transducers is mounted on the base. Each capacitive ultrasound transducer element and the ultrasound transducer are specifically constructed to achieve select desired performance characteristics. The ultrasound transducer may have an angular beam spread through a gaseous medium of greater than 15 degrees and an attenuation loss through the gaseous medium of greater than 10 dB measured at a distance 12.5 mm to 25 mm along a primary transmission axis of the ultrasound transducer. The ultrasound transducer may be particularly useful for characterizing fluid behind an ear drum to diagnose otitis media.

The utility model belongs to the technical field of medical nursing materials, and particularly relates to a device for preventing water from entering an ear canal after a child otitis media operation, which comprises an earmuff used for wrapping the ear of a child, the inner end of the earmuff is provided with a containing protection cavity used for containing the ear of the child, and the earmuff is provided with a reinforcing sheet, a first waterproof adhesive and a protection cover. The ear protection cover is used for covering the outer end of the ear of a child patient, the ear of the child patient can be effectively protected, liquid is prevented from entering the ear canal of the child patient to cause the infection phenomenon, the ear canal of the child patient can be protected, and the ear canal of the child patient can be protected from being infected. Meanwhile, due to the arrangement of the double waterproof mucilage glue, the fixing effectiveness and the waterproof performance can be further improved, and the situation that normal use of the waterproof function is affected due to the fact that the double waterproof mucilage glue falls off is prevented.

According to the construction method and application of the acute otitis media Bama miniature pig model, the acute otitis media Bama miniature pig model which is easy to operate, high in success rate, typical in symptom and high in postoperative survival rate is established, and the acute otitis media Bama miniature pig model is used for research on acute otitis media pathogenesis and treatment schemes. And a new way is provided for the treatment research of acute otitis media.

Provided are topically administered pharmaceutical compositions for the treatment of fungal infected eye and ear diseases, such as fungal keratitis, otitis externa or otitis media caused by fungal infection, and methods of making the same. The pharmaceutical composition comprises a triazole antifungal agent as an active ingredient, a non-aqueous solvent and an optional tension regulator, and can be a non-aqueous composition without preservatives. The non-aqueous composition has one or more of the following advantages: the non-aqueous composition is high in stability, free of preservatives and low in irritation, the concentration of antifungal drugs in local tissues is increased, the toxic and side effects of the whole body are reduced, the residence time of the antifungal drugs in the local tissues is prolonged, the administration frequency is reduced, and the compliance of patients is improved.

A composition includes a therapeutic compound, a liposome shell, and a pharmaceutically acceptable carrier comprising a stimuli-responsive hydrogel encapsulating the therapeutic compound. The liposome shell includes a plurality of hydroxyl-containing lipids.

The invention belongs to the technical field of medicines, and particularly relates to a tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet as well as a preparation method and application of the tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet. The preparation method comprises the following steps: preparing a copper indium phosphorus sulfur nanosheet; then connecting tannic acid with the copper indium phosphorus sulfur nanosheet through a Fenton reaction to obtain a tannic acid modified copper indium phosphorus sulfur nanosheet; and finally, reacting the amino-modified aptamer with tannic acid to jointly modify the copper-indium-phosphorus-sulfur nanosheet, so as to obtain the tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet. The tannic acid and aptamer modified copper indium phosphorus sulfur nanosheet can simultaneously have dsDNA and NETs / EETs binding capacity, RONS removal capacity and antibacterial capacity, and shows an excellent regulation effect on disordered inflammation in a secretory otitis media rat model so as to improve hearing loss.

The invention relates to a compound ear drop for treating otitis media, which comprises chloramphenicol, dexamethasone sodium phosphate, a stabilizer, a preservative, a pH regulator, a chelating agent and a solvent, and the weight ratio of chloramphenicol to dexamethasone sodium phosphate is (1-4): 1. The stabilizer is selected from one or more of sodium hyaluronate, polyethylene glycol, povidone, polyvinylpyrrolidone and poloxamer. The ear drops take effect quickly when being used for treating ear diseases, symptoms can be relieved basically after the ear drops are generally used for 3-4 days, after the symptoms are relieved, the ear drops can be re-diagnosed or reduced to be used for one week, and due to the fact that the effect taking time and the treatment course are short, adverse side effects hardly occur.

The invention discloses application of an umbilical cord mesenchymal stem cell exosome in preparation of a medicine for treating otitis media. Belongs to the technical field of biological medicine. The hUCMSCs-Exos extracted by the invention can obviously improve mouse hearing function loss caused by otitis media, relieve pathological injury of middle ear tissues caused by otitis media, relieve local inflammatory factor expression in middle ears and relieve otitis media symptoms. Different from traditional antibiotic drugs, hUCMSCs-Exos provides a brand new drug candidate and a treatment method for clinically solving otitis media.

The present application discloses a kind of composite nanoparticles, including inorganic nanoparticles and polypeptide attached to the surface of the inorganic nanoparticles.The composite nanoparticles of the present application can overcome bacterial drug resistance and better treat otitis media.

The invention relates to the technical field of otitis media treatment, and provides a medicine formula for non-surgical treatment of suppurative otitis media and a use method of the medicine formula. 3-9g of dried alum; 1-3 g of borneol; 6-12 g of rheum officinale; 10 to 15g of fructus forsythiae; 10 to 15 g of isatis root; the medicine provided by the invention is simple in formula, convenient to prepare, remarkable in curative effect and small in side effect, is a safe and effective method for non-surgical treatment of the suppurative otitis media, is suitable for treating the suppurative otitis media, particularly acute suppurative otitis media and chronic suppurative otitis media in the acute attack stage, and has a wide application prospect. Through the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and astringing and promoting tissue regeneration, symptoms such as ear pain and suppuration can be rapidly relieved, repair of auditory meatus mucous membranes and tympanic membranes is promoted, cleaning cotton is prevented from falling into auditory meatus when fester is cleaned through the specially-made medicine feeding device, and the safety of non-surgical treatment for treating suppurative otitis media is improved.

This invention belongs to the field of medical information technology and relates to a method and system for constructing a rat model of secretory otitis media. Specifically, it includes: performing modeling treatment on experimental rats and collecting initial tympanic membrane response data to construct an initial middle ear state; applying controlled perturbation to the middle ear and simultaneously collecting response data during the perturbation process, extracting dynamic response features and identifying feature points to obtain the corresponding perturbation intensity; constructing response trajectories during loading and recovery based on the perturbation intensity and extracting trajectory difference features; combining perturbation data from different directions to extract directional response features and directional response difference features; fusing the perturbation intensity, trajectory difference features, and directional response difference features to construct a middle ear fluid state determination model and calculate middle ear fluid state parameters; and screening experimental rats to determine individuals where the model construction is complete. This invention also discloses a corresponding system. This invention can achieve stability and reproducibility in constructing a secretory otitis media model.

The invention belongs to the technical field of medical equipment, and discloses an intelligent temperature control flushing device for otitis media treatment, the intelligent temperature control flushing device comprises a flushing base body, the flushing base body is connected with a liquid storage box body, a liquid drawing assembly, a heating assembly and a control module, the liquid drawing assembly comprises a liquid drawing box body and a motor, and the liquid drawing box body is provided with a liquid drawing chamber; a liquid drawing gear is arranged on the inner side of the liquid drawing chamber, the liquid drawing chamber is communicated with the liquid storage box body through a liquid drawing pipe, the liquid drawing chamber is communicated with a liquid guide cylinder, and the liquid guide cylinder is communicated with a flushing head through a liquid guide pipe; the heating assembly comprises a sliding rod, a heating resistor and a storage battery, the heating resistor is arranged on the outer side of the liquid guide pipe in a sleeving mode, the sliding rod abuts against the heating resistor in a sliding mode, and the sliding rod and the heating resistor are electrically connected with the positive electrode and the negative electrode of the storage battery respectively. According to the ear canal flusher, the liquid suction assembly is used for sucking flushing liquid to flush the ear canal, and the flushing flow and pressure are controllable; the heating assembly is used for heating the sucked flushing fluid, and the temperature of the flushing fluid is constant and uniform during flushing.

A tympanic membrane classification device (30) is provided with: a communication unit into which image data including a tympanic membrane is input; a first classification unit (31b) that uses an algorithm to extract characteristics from the inputted image data and classifies the tympanic membrane as acute otitis media or as other than acute otitis media; and a second classification unit (31c) that uses an algorithm to extract characteristics from the image data classified as other than acute otitis media and classifies the tympanic membrane as normal or exudative otitis media, and the tympanic membrane classification device (30) outputs information on acute otitis media or normal tympanic membrane or exudative otitis media from the communication unit on the basis of the classification results of the first classification unit (31b) and the second classification unit (31c).

An eardrum classification apparatus 30 includes: a communication unit that receives an input of image data including an eardrum; a first classification unit 31b that extracts features from the input image data by using an algorithm and classifies the eardrum as having acute otitis media or something other than acute otitis media; and a second classification unit 31c that extracts features, by using an algorithm, from the image data classified as having something other than acute otitis media, and classifies the eardrum as being normal or having exudative otitis media. On the basis of the classification results given by the first classification unit 31b and the second classification unit 31c, the communication unit provides an output indicating acute otitis media, normal eardrum, or exudative otitis media.