14 results about "Media otitis" patented technology

The embodiment of the invention provides a clinical intervention decision-making method and device, electronic equipment and a storage medium, and belongs to the technical field of artificial intelligence. The method comprises the steps that secretory otitis media clinical data of a to-be-evaluated user are acquired, and the secretory otitis media clinical data comprise multiple etiological clinical features; obtaining a target secretory otitis media disease probability prediction model; on the basis of a target secretory otitis media disease probability prediction model, performing feature evaluation on the clinical features of the multiple etiologies to obtain multiple user feature scores; based on the target secretory otitis media disease probability prediction model and the plurality of user feature scores, performing disease probability prediction on the to-be-evaluated user to obtain user disease prediction data; and based on the user disease prediction data, performing clinical intervention decision on the to-be-evaluated user. According to the application, the secretory otitis media can be effectively prevented, the accuracy of clinical intervention decisions can be improved, and in addition, the treatment effect of the secretory otitis media can be effectively evaluated.

This invention discloses a wearable ultrasound delivery device for treating otitis media, comprising a wearable main body with a flexible structure adapted to the shape of the patient's ear canal, and a through-hole central channel; an ultrasound drug delivery device, detachably disposed within the central channel, comprising a drug carrier for carrying the therapeutic drug to be delivered, an ultrasound transducer assembly for providing an ultrasound-guided drug delivery mode, and a handheld controller for adjusting the millimeter-level displacement of the drug carrier into the middle ear cavity; wherein, the ultrasound transducer assembly comprises a flexible substrate and multiple piezoelectric transducer units integrated on the flexible substrate, the multiple piezoelectric transducer units constituting a phased array transducer array. This device solves the technical problems of inaccurate drug delivery, low drug delivery efficiency, inability to adapt to the ear canal structure, and complex operation in the prior art.

The present invention relates to a middle ear inflammation treatment device. Disclosed is a middle ear inflammation treatment device installed with a ventilation tube, the device comprising: a handle; a cutting sheath connected to the handle and having a tubular shape with an inner diameter greater than an outer diameter of the ventilation tube, and wherein the ventilation tube is inserted into the cutting sheath; and a suction tube formed to be relatively movable to the cutting sheath in a length direction of the cutting sheath within the cutting sheath, wherein the suction tube has a tubular shape to suck and remove exudate in a middle ear through the suction tube; and a moving tool located outside the handle and relatively moving the suction tube to the cutting sheath.

The invention discloses a chronic otitis media CT report automatic generation system based on a visual-language large model, and belongs to the technical field of radiation medicine. The system comprises a data acquisition and processing module for acquiring image data and text data and preprocessing the data; the vision-language large model training module is used for inputting the preprocessed data into a vision-language large model for training and adjusting and optimizing model parameters; and the report generation interaction module is used for generating a structured report by utilizing the trained vision-language large model. According to the system, the visual-language large model is applied to the field of CT report generation and typing diagnosis of chronic otitis media for the first time, the technical blank in the field is filled, and a new path is developed for intelligent diagnosis of chronic otitis media.

The embodiment of the application discloses an otological image intelligent identification method based on a multi-modal artificial intelligence, and comprises the following steps: acquiring an otological image and clinical text information of a patient; fusing the otological image and the clinical text information to obtain multi-modal features; and identifying the multi-modal clinical text information features by using a multi-model integrated architecture to automatically determine the tympanic membrane state of the patient, wherein the tympanic membrane state comprises a normal tympanic membrane, a perforation, an inward protrusion, an effusion, a suppurative otitis media, calcification and otosclerosis. The embodiment realizes automatic intelligent identification of the tympanic membrane state.

An ultrasonic transducer can include a plurality of capacitive ultrasonic transducer elements and a base having a maximum dimension sized and shaped to be disposed within an external ear canal, wherein the plurality of capacitive ultrasonic transducer elements are mounted on the base. Each capacitive ultrasonic transducer element and the ultrasonic transducer are specifically constructed to achieve selected desired performance characteristics. The ultrasonic transducer can have an angular beam that propagates through a gaseous medium that is greater than 15 degrees and an attenuation loss through the gaseous medium that is greater than 10 dB measured at a distance of 12.5 mm to 25 mm along a primary transmission axis of the ultrasonic transducer. The ultrasonic transducer can be particularly useful for characterizing fluid behind a tympanic membrane to diagnose otitis media.

According to the construction method and application of the acute otitis media Bama miniature pig model, the acute otitis media Bama miniature pig model which is easy to operate, high in success rate, typical in symptom and high in postoperative survival rate is established, and the acute otitis media Bama miniature pig model is used for research on acute otitis media pathogenesis and treatment schemes. And a new way is provided for the treatment research of acute otitis media.

The invention belongs to the technical field of medicines, and particularly relates to a tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet as well as a preparation method and application of the tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet. The preparation method comprises the following steps: preparing a copper indium phosphorus sulfur nanosheet; then connecting tannic acid with the copper indium phosphorus sulfur nanosheet through a Fenton reaction to obtain a tannic acid modified copper indium phosphorus sulfur nanosheet; and finally, reacting the amino-modified aptamer with tannic acid to jointly modify the copper-indium-phosphorus-sulfur nanosheet, so as to obtain the tannic acid and aptamer modified copper-indium-phosphorus-sulfur nanosheet. The tannic acid and aptamer modified copper indium phosphorus sulfur nanosheet can simultaneously have dsDNA and NETs / EETs binding capacity, RONS removal capacity and antibacterial capacity, and shows an excellent regulation effect on disordered inflammation in a secretory otitis media rat model so as to improve hearing loss.

The invention discloses application of an umbilical cord mesenchymal stem cell exosome in preparation of a medicine for treating otitis media. Belongs to the technical field of biological medicine. The hUCMSCs-Exos extracted by the invention can obviously improve mouse hearing function loss caused by otitis media, relieve pathological injury of middle ear tissues caused by otitis media, relieve local inflammatory factor expression in middle ears and relieve otitis media symptoms. Different from traditional antibiotic drugs, hUCMSCs-Exos provides a brand new drug candidate and a treatment method for clinically solving otitis media.

The present application discloses a kind of composite nanoparticles, including inorganic nanoparticles and polypeptide attached to the surface of the inorganic nanoparticles.The composite nanoparticles of the present application can overcome bacterial drug resistance and better treat otitis media.

This invention belongs to the field of medical information technology and relates to a method and system for constructing a rat model of secretory otitis media. Specifically, it includes: performing modeling treatment on experimental rats and collecting initial tympanic membrane response data to construct an initial middle ear state; applying controlled perturbation to the middle ear and simultaneously collecting response data during the perturbation process, extracting dynamic response features and identifying feature points to obtain the corresponding perturbation intensity; constructing response trajectories during loading and recovery based on the perturbation intensity and extracting trajectory difference features; combining perturbation data from different directions to extract directional response features and directional response difference features; fusing the perturbation intensity, trajectory difference features, and directional response difference features to construct a middle ear fluid state determination model and calculate middle ear fluid state parameters; and screening experimental rats to determine individuals where the model construction is complete. This invention also discloses a corresponding system. This invention can achieve stability and reproducibility in constructing a secretory otitis media model.

The invention belongs to the technical field of medical equipment, and discloses an intelligent temperature control flushing device for otitis media treatment, the intelligent temperature control flushing device comprises a flushing base body, the flushing base body is connected with a liquid storage box body, a liquid drawing assembly, a heating assembly and a control module, the liquid drawing assembly comprises a liquid drawing box body and a motor, and the liquid drawing box body is provided with a liquid drawing chamber; a liquid drawing gear is arranged on the inner side of the liquid drawing chamber, the liquid drawing chamber is communicated with the liquid storage box body through a liquid drawing pipe, the liquid drawing chamber is communicated with a liquid guide cylinder, and the liquid guide cylinder is communicated with a flushing head through a liquid guide pipe; the heating assembly comprises a sliding rod, a heating resistor and a storage battery, the heating resistor is arranged on the outer side of the liquid guide pipe in a sleeving mode, the sliding rod abuts against the heating resistor in a sliding mode, and the sliding rod and the heating resistor are electrically connected with the positive electrode and the negative electrode of the storage battery respectively. According to the ear canal flusher, the liquid suction assembly is used for sucking flushing liquid to flush the ear canal, and the flushing flow and pressure are controllable; the heating assembly is used for heating the sucked flushing fluid, and the temperature of the flushing fluid is constant and uniform during flushing.

A tympanic membrane classification device (30) is provided with: a communication unit into which image data including a tympanic membrane is input; a first classification unit (31b) that uses an algorithm to extract characteristics from the inputted image data and classifies the tympanic membrane as acute otitis media or as other than acute otitis media; and a second classification unit (31c) that uses an algorithm to extract characteristics from the image data classified as other than acute otitis media and classifies the tympanic membrane as normal or exudative otitis media, and the tympanic membrane classification device (30) outputs information on acute otitis media or normal tympanic membrane or exudative otitis media from the communication unit on the basis of the classification results of the first classification unit (31b) and the second classification unit (31c).

A system and method are disclosed for the remote detection of otitis media in children at home or in other locations for use in a telemedicine environment. The system runs on a smartphone application and is easy for a child's caregiver to use. The system also includes a pop-open soundwave guide that directs an audio signal from a smartphone's speaker to the patient's eardrum and back to the smartphone's microphone.