Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation

A technology for wound repair and skin regeneration, which is applied to skin diseases, pharmaceutical formulas, medical preparations with non-active ingredients, etc., to achieve the effects of good skin elasticity, low price, and easy operation

Active Publication Date: 2012-07-25
江苏慰泽创伤医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the wound secretions need to be scraped off when changing the dressing, and the wound heals slowly, it is easy to cause wound infection and scar hyperplasia, which brings pain to the patient
[0004]2. In terms of application method, since the moist burn ointment must constantly scrape off the wound secretions, it often touches the growth of fresh granulation on the wound surface, especially the residue on the easily damaged wound surface. Skin islands, resulting in prolonged wound healing, especially in patients with unbearable pain within seven days after burns
[0005]3. MEBO is expensive and used in a large amount, which is generally unbearable for patients with large areas, and the healing of pure third-degree wounds with small areas is slow, and a small number of patients are prone to allergies cause wound ulceration
[0006] At present, there is a lack of effective treatment drugs for deep burn wounds, especially repair drugs for deep second-degree burn wounds, or mixed deep second-degree and third-degree burn wounds

Method used

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  • Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation
  • Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation
  • Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] By weight: 100 parts of bletilla striata, 1 part of camphor, and 0.1 part of borneol;

[0063] Weigh raw materials according to the above formula, crush and sieve Bletilla striata over 60 meshes; dissolve camphor and borneol in ethanol solution, add Bletilla striata, add water to suspend, heat to obtain finished product directly or concentrate to extract to obtain finished product, bottled , 121 ° Celsius high pressure or cobalt 60 radiation sterilization. The above-mentioned heating conditions are 80° C. for 50 minutes; the ethanol is 95% ethanol.

[0064] Liu XX male, 30 years old, employee of Yancheng Institute of Technology, in April 1991, the boiler boiled water to account for 65% of the body surface area and had a deep second degree burn. After being treated by the present invention for 15 days, the dressing was changed once a day for treatment. The wound surface healed without any scars, and the skin smooth normal.

Embodiment 2

[0066] By weight: 100 parts of bletilla striata, 10 parts of camphor, and 5 parts of borneol. Weigh raw materials according to the above formula, crush and sieve Bletilla striata over 60 meshes; dissolve camphor and borneol in ethanol solution, add Bletilla striata, add water to suspend, heat to obtain finished product directly or concentrate to extract to obtain finished product, bottled , 121 ° Celsius high pressure or cobalt 60 radiation sterilization. The above heating conditions are 100° C. for 60 min; the ethanol is 65% ethanol.

[0067] Yao X, male, 29 years old, employee of Yancheng Institute of Technology, suffered mixed deep II°~III° burns on both lower limbs accounting for 15% of the body surface area due to lime in July 1989, and needed skin grafting for 31 days in the Burn Department of the First Hospital of Yancheng City. After 23 days of treatment, the dressing was changed once a day, and the skin was cured without skin grafting. Now both lower limbs have no sc...

Embodiment 3

[0069] By weight: 90 parts of bletilla striata, 1 part of camphor, and 0.1 part of borneol. Weigh raw materials according to the above formula, crush and sieve Bletilla striata over 60 meshes; dissolve camphor and borneol in ethanol solution, add Bletilla striata, add water to suspend, heat to obtain finished product directly or concentrate to extract to obtain finished product, bottled , 121 ° Celsius high pressure or cobalt 60 radiation sterilization. The above-mentioned heating conditions are 90° C. for 50 minutes; the ethanol is 75% ethanol.

[0070] Wu XX male, 25 years old, on August 26, 1993, due to deep II°~III° burns accounting for 50% of the body surface area, he was treated by the Burn Department of the First Hospital of Yancheng City for 2 days and then treated by the present invention. The dressing was changed once a day. Days of treatment, he recovered and was discharged from the hospital, with no scars and no dysfunction. (Note: The comparison photos before an...

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PUM

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Abstract

The invention belongs to a traditional Chinese preparation, in particular to a traditional Chinese medicine recipe for restoring deep burnt wound, promoting tissue regeneration and inhibiting scar hyperplasia. A traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion is characterized by comprising the following ingredients in parts by weight: 0.1 to 100 parts of bletilla, 0.1 to 10 parts of camphor and 0.1 to 5 parts of borneol. The traditional Chinese compound preparation can be used for treating residual burn wound surfaces, chilblain, bedsore, deep skin scratch, lower limb ulcer and chemoradiotherapy skin tissue injury, the restoration is fast, and the effect is obvious.

Description

technical field : [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine formula for repairing deeply burned wounds, promoting tissue regeneration and inhibiting scar hyperplasia. Background technique : [0002] Burns mainly refer to damage to the skin, mucous membranes, and even deep tissues caused by heat, chemicals, electric energy, and radiation. Among them, skin thermal burns (such as flames, boiling water, etc.) are the most common. According to statistics, the number of deaths due to accidental injuries every year, burns are second only to traffic accidents, ranking second, and there are also a large number of wounded combined with burns in traffic accident injuries. The annual incidence of burns in China is about 1.5% to 2%, that is, about 20 million people suffer from burns of varying degrees every year, and about 5% of burn patients need hospitalization. The ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K47/32A61K47/34A61K47/36A61K47/38A61P17/02A61K31/045A61K31/125A61K31/635A61K31/496A61K33/06A61K33/22A61K33/24
Inventor 沈慰平
Owner 江苏慰泽创伤医药有限公司
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