300 results about "Radiation Sterilization" patented technology

A surgical instrument including a first portion and a second portion, wherein the second portion can be sterilized separately from the first portion. The first portion can comprise an anvil, a staple cartridge channel and / or staple cartridge, and a movable cutting member. The second portion can comprise electronic components configured to control the surgical instrument and / or record data collected during the use of the surgical instrument. The first portion can be sterilized using a gamma radiation sterilization process while the second portion can be sterilized using a different sterilization process, such as steam, ethylene oxide, ozone, and / or hydrogen peroxide sterilization processes, for example. As a result, the first and second portions can be sterilized separately and delivered in two separate containers. The second portion can be stored within a sealed bag and can include an electrical terminal which can penetrate the bag and communicate with the first portion.

Applicators for storing, sterilizing, and dispensing adhesives are provided. The applicators comprise a porous tip, a body, and a container containing a polymerizable cyanoacrylate monomer adhesive. The applicators are sterilized by radiation, and following sterilization, the adhesive remains substantially unpolymerized for about twenty four months.

The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprises (a) a release region and (b) at least one therapeutic agent and the release region comprises a phenoxy resin block.

The present invention provides, among other things, sterilization containers, inner bags, and methods for the radiation sterilization of liquid products. In particular, the invention provides sterilization containers for the irradiation sterilization of a pooled volume of liquid product greater than about, fifteen liters, and methods for the irradiation sterilization of liquid products.

A radiation sterilization method of a disposable medical device and a manufacturing method are provided, which method comprising the steps of packaging a disposable medical device, which has applied thereto with hydrophilic polymer coating, with a gas permeable packaging material, controlling a product moisture content of the thus packaged medical device by maintaining the device in a given humidity atmosphere for not less than a time at which an equilibrated moisture content is reached, and subjecting, to radiation sterilization, the medical device whose product moisture content has been controlled, so that an eluted matter is reduced in amount and a sliding performance is ensured according to the radiation sterilization method of the hydrophilic polymer-coated, disposable medical device and the manufacturing method.

Highly expandable materials have been developed for filling an aneurysm sac and for sealing of endoluminal devices vessel walls. The expandable materials have appropriate chemical and physical properties to withstand radiation, sterilization, or storage in sterilizing solution, without loss of expandable characteristics. The expandable materials may contain protectants, prophylactic, diagnostic, therapeutic, or imaging agents. The expandable materials form a seal that actively conforms to vascular anatomy sealing any leaks that may occur after device implantation. In one embodiment, the technology is used to prevent leaks associated with abdominal aortic aneurysm (AAA) repair, especially for complex AAA repair.

The invention provides a natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing which is composed of a backing layer, a hydrogel dressing layer and a strippable layer. A synthesis method of the natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing comprises performing radiation crosslinking on raw materials, namely 10-40% of natural polysaccharide, 0.1-10% of nano-TiO2, 0.1%-5% of radiation sensitizer, 0.1%-3% of pH regulator, 0.1%-3% of surfactant and 60%-95% of water, by use of an electron beam or gamma ray by a radiation dose of 10-150kGy and at a dose rate of 10-80kGy / pass. The natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing is sheared, bagged and sterilized by radiation, and then stored for a long time. The natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing has the advantages that the maximization and optimization of the properties of the composite hydrogel, light-sensitive and antimicrobial properties are united organically, and the multiple-element composite synergic antimicrobial effect of the nano-TiO2-natural polysaccharide hydrogel is also realized; meanwhile, the composite hydrogel dressing has the characteristics of air permeability, no bonding with tissues, good flexibility and the like, and thus is suitable for protecting and treating various wounds.

Sterilizable separator tubes and methods of utilization of same are presented. Methods include providing a separator tube containing a separator substance that can be polymerized to a desired hardness following sterilization using radical generating radiation. The separator substance is formulated to have a density between that of the average densities of separable fractions derived from a sample fluid such as blood, and to be flowable. Upon centrifugation of a separator tube containing a fluid sample, the separator substance forms a barrier between the fractions. The barrier subsequently hardens to form a solid barrier when triggered by a suitable energy source.

Disclosed herein is a method of radiation sterilizing a plurality of medical devices.

The invention provides a method for quickly aging and tenderizing beef, which comprises the following steps: during the beef chilling aging process, cattle pancreas is prepared into homogenate; Ca2+ is utilized to activate various zymogens in the pancreas; active pancreas injection solution is prepared and directly injected into the beef, so that trypsin in the beef can decompose muscle protein; and simultaneously, by the action of ultrasonic wave, the original structure of muscle is damaged, the tenderness is improved, the aging purpose can be achieved within three to five days, and the natural aging time can be shortened by about 50%. In the aspect of keeping quality, vacuum packaging and radiation sterilization are combined, so that the storage period of the cut beef can be prolonged for 3-5 times; in the aspect of the quality of the beef, the cut beef prepared by the method has organoleptic, physicochemical and other indexes which can meet the requirements of 'GB2707 Hygienic Standard for Fresh (Frozen) Meat of Livestock'; and the cutting force is 4.2-5.3kg, and people can obtain the best mouthfeel. The method maintains the specific flavor and nutrition of the beef, and has the characteristics of quick aging speed, long shelf life, energy saving effect and high production efficiency.

A biological material for medical purpose, and method for preparation and use, the preparing method includes taking collagen or gelatin 30-70 parts, gluglucosan 20-40 parts, chondroitin sulfate 0-40 parts and chitosan 0-40 parts. The preparing process comprises the steps of stirring homogeneously, decompressing, de-aerating, drying, steeping, deionized water washing, drying, split charging, packaging, and radiation sterilization treatment.

A method for inhibiting adverse reaction of the contents of a prefilled container during a radiation sterilization procedure is disclosed. In the method, a container which is made of a material including a radiation stable polyolefin is prefilled with a medium prior to being subjected to a gamma irradiation sterilization treatment. By using a radiation stable polyolefin material as the container, such as a polyolefin with a radiation stabilizer additive, and by prefilling the container prior to the gamma irradiation treatment, the container can be effectively sterilized without adversely affecting its contents.

Disclosed herein is a method of radiation sterilizing a plurality of medical devices.

The present invention provides a method of using a medical tubing with a pump for administering measured amounts of a beneficial fluid over time to a patient comprising the steps of providing a tubing having a first layer selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the copolymers of ethylene are an ethylene monomer copolymerized with at least one monomer selected from the group consisting of lower alkyl olefins, lower alkyl esters of a carboxylic acid, and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene having from 3 to 18 carbons, the tubing having been exposed to a sterilization dosage of radiation of from about 15 to about 45 kGys; and pumping fluid through the tubing with the pump.

The invention discloses a preparation method of a functional hydrogel medical dressing. The preparation method comprises the following steps: 1. blending a biopolymer material, a chemical synthesized polymer material, a transforming growth factor TGF-beta and distilled water so as to form a physical-crosslinked hydrogel, wherein the biopolymer material consists of carboxymethyl chitosan, chitosan quaternary ammonium salt, gelatin, gellan gum and sodium alginate; and the chemical synthesized polymer material consists of polyvinyl alcohol and polyvinylpyrrolidone; 2. coating and processing the physical-crosslinked hydrogel obtained in the step 1 by virtue of a coating machine; and 3. conducting radiation sterilization on the hydrogel which is coated in the step 2, and implementing radiation crosslinking during the process of radiation sterilization. The method, through physical crosslinking and radiation crosslinking, can form the hydrogen of a dual-network structure; and the hydrogel medical dressing is high in strength and melting-up property, and the dressing is capable of protecting wound surfaces, stopping bleeding, relieving pain, inhibiting bacteria and promoting the growth of epithelial cell.

The invention discloses bioprotein sponge and a preparation method thereof. According to the characteristics that internal cells of a human body and an animal body adapt to cell growth environments, the bioprotein is freezed into a dry sponge shape through freeze drying technology by utilizing intercellular substances as controlled-release carrieres of growth factors and acts on the trauma of the human body or the animal body in controlled-release medicament feeding mode. The preparation method of the bioprotein sponge changes the traditional preparation process, adopts S / D virus inactivation, and adds protective agent to reduce probability of virus cross infection of people and livestock simultaneously. The CM cation chromatographic purification process improves purity of bioprotein, promotes stanching and tissue union effect of the bioprotein sponge and reduces clinical side effect. An ultrafiltration process is adopted to replace a dialysis process, so that preparation period is shortened, activity of the bioprotein is protected, and production cost is reduced. A method of heating inactivation virus replaces the method of cobalt60 radiation sterilization, so that the fact that radiation rays bring damage to products is avoided, the activity of the bioprotein is protected, and safe and reliable use of products in clinical application is achieved.

Methods are disclosed for conditioning a polymeric stent after sterilization, and / or after crimping and before packaging, such that the properties of the polymeric stent fall within a narrower range of values. The stent is exposed to a controlled temperature at or above ambient for a period of time after radiation sterilization and / or after crimping and before sterilization. As a result, the polymeric stent properties, particularly radial strength and number-average molecular weight of the polymer of the polymeric stent, fall within a narrower range.

The invention discloses amorphous hydrocolloid dressing formed by high-energy ray irradiation proper crosslinking. The amorphous hydrocolloid dressing disclosed by the invention has good deformability, film forming property, moisture retention, biocompatibility and wound healing facilitation, and can protect various surgical incisions, cover various acute and chronic wounds and wound surfaces, prevent infection, accelerate healing and relive cicatrization. The amorphous hydrocolloid dressing is suitable for the filling covering protection on various wounds with tissue defects and for the protection and treatment of the surgical incisions and burns and scales including the wound surfaces formed by chemical burns as well as various acute and chronic wounds and wound surfaces. Moreover, through radiation sterilization, the amorphous hydrocolloid dressing can be stored for a long time. The formula of the amorphous hydrocolloid dressing disclosed by the invention comprises the following components in percentage by weight: 2-8% of sodium carboxymethylcellulose, 1-6% of chitosan and the balance of water. The amorphous hydrocolloid dressing also can comprise 0.1-0.3% of silver nitrate or silver chloride, 3-8% of polyvinyl alcohol, 15-25% of propylene glycol and the like all by weight. The amorphous hydrocolloid dressing is subjected to high-energy ray irradiation proper crosslinking and sterilization, thus the irradiation dose is 5-15KGy.

The invention provides a method for preparing radiation and aging resistant polypropylene alloys. Reactive hindered amine stabilizers are grafted on a polypropylene molecular chain by a reactive extrusion method to improve the aging resistance of materials after the alloys are subjected to radiation sterilization. The radiation and aging resistant polypropylene alloys prepared by a reactive grafting method have the advantages of uniform dispersion of the stabilizers, difficult precipitation, durable aging resistance and the like. The radiation and aging resistant polypropylene alloys have simple preparation method, have no pollution to the environment, and are easy to realize mass continuous production. The radiation and aging resistant polypropylene alloys prepared by the method can be applied in fields such as medical infusion instruments, food packaging, medicament packaging and the like; and after a radiation sterilization method is adopted for sterilization and within one year of storage period, the elongation at break of products is reduced and is less than 50 percent, the tensile strength is reduced and is less than 2MPa, and the yellowness index is increased and is less than 1. Therefore, the radiation and aging resistant polypropylenes have strong radiation and aging resistance.

The present invention discloses a factory processing and sterilization method of a crab paste, which contains processing method of the flavoring with tea polyphenol and radiation sterilization. The processed crab paste is packed into quantitative soft package plastic cup, sealed with plastic film, sterilized by r-ray that produced by isotope cobalt 60, and stored in cold storage with the temperature is below -6 centigrade. The process steps have the following procedures: selecting materials, cleaning the materials, clearing the materials, crushing the materials, burdening, packing in cup, sterilizing and storing. The present invention is characterized in that tea polyphenol is added and materials need to be sterilized by radiation. The crab paste belongs to salted food, so the sterilization can not be use high temperature or other disinfectants to marinate, and r-ray produced by isotope cobalt 60 is used to sterilize is the best way. The present invention is packed by innocuous transparent plastic soft package, the target is: first, the product can be taken, opened and eaten conveniently; second, the package will not become dark after the package is sterilized by radiation, while the glass bottle will, so the appearance is not influenced.

A sensor device has an optical sensor (1), a container (2) and a compartmentalizer (3) that temporarily divides the container into a main space (4) and an adjacent space (5), in which the optical sensor (1) is located. The gas volume in the direct vicinity of the optical sensor (1) is reduced, as are also, consequently, the reactive products generated by radiation sterilization. The adjacent space (5) can be united with the main space (4) after the sterilization as a result of the temporary compartmentalization. The optical sensor is suitable for implementation in containers and laboratory products, such as, for example, disposable bioreactors, that are sterilized by gamma radiation.

A radiation sterilization method of a disposable medical device and a manufacturing method are provided, which method comprising the steps of packaging a disposable medical device, which has applied thereto with hydrophilic polymer coating, with a gas permeable packaging material, controlling a product moisture content of the thus packaged medical device by maintaining the device in a given humidity atmosphere for not less than a time at which an equilibrated moisture content is reached, and subjecting, to radiation sterilization, the medical device whose product moisture content has been controlled, so that an eluted matter is reduced in amount and a sliding performance is ensured according to the radiation sterilization method of the hydrophilic polymer-coated, disposable medical device and the manufacturing method.

The invention discloses a novel process of performing pine pollen fermentation by probiotics. The process comprises the following steps of: (1) collecting pine pollen, timely drying the pine pollen in the sun, sieving the pine pollen for removing impurities, and carrying out drying treatment on the sieved pine pollen; (2) carrying out sterilization treatment on the pine pollen by a 60Co gamma radiation sterilization process; (3) carrying out fermentation by lactobacillus plantarum Lp-115 and lactobacillus paracasei Lpc-37 which are taken as pine pollen zymogens; and (4) after the fermentation is ended, drying a fermentation product in a drying box at 40-50 DEG C or performing reduced pressure evaporation on the fermentation product until the water content of the product is 5%-7%. The novel process for performing pine pollen fermentation by plantarum Lp-115 and lactobacillus paracasei Lpc-37 has the beneficial effects that the solubility, mouthfeel and special flavor of the pine pollen can be significantly improved, the nutritional value of the pine pollen is improved, and the crude protein content of the fermented pine pollen is enhanced by more than 16.89%. Moreover, the amount of active probiotics in the fermented pine pollen can reach 9.21*109cfu / g, so that the pine pollen has the efficacies of pollen and probiotics, and can be taken as an ideal ingredient of a health care product.

The invention discloses a ship ballast water treating method which comprises the following steps: (1), filtering seawater by a filter; (2), carrying out ozone oxidization and sterilization; (3), carrying out ultrasonic-wave cavitation and sterilization; (4), carrying out ultraviolet sterilization; (5), conveying the water into a ballast bin as ballast water; (6), carrying out back-flushing with seawater for a filter after a ballasting process is ended; (7), treating according to the steps (2), (3) and (4) before the ballast water is exhausted; (8), exhausting the treated and qualified ballast water. According to the invention, synergistic effects of ozone oxidization and sterilization, ultrasonic-wave cavitation and sterilization and ultraviolet-light radiation sterilization are performed, equipment is small in size, low in energy consumption, high in treating efficiency and wide in range of application. Moreover, treatment scale can be flexibly regulated by increasing or reducing number of ozone generators, ultrasonic transducers, low-pressure mercury lamps, so that the treatment capacity can be 20m<3> / h-5000m<3> / h. Besides, organic pollutants in seawater can be degraded while microorganisms are killed, so that the water quality of the exhausted ballast water is improved.

A method of making a ready-to-use catheter assembly and a ready-to-use catheter are provided, which avoids any degradation of the catheter during sterilization. The method comprises: placing a catheter with a hydrophilic coating and a wetting fluid in a catheter package made of low moisture transmission material while the package is in a first condition wherein an insertable length of the hydrophilic coating of the catheter is not in contact with the wetting fluid, sterilizing the catheter package with the catheter and the wetting fluid by radiation sterilization while the catheter package is kept in a condition in which the insertable length is not in contact with the wetting fluid, transferring the catheter package with the catheter and the wetting fluid into a second condition, bringing the wetting fluid into contact with at least the insertable length and activating the insertable length via gravity and / or via inertia.

The present invention discloses rosa sterilis var. leioclada enzymes based on liquid fermentation and a preparation method thereof. The rosa sterilis var. leioclada is washed and cleaned, the cleaned rosa sterilis var. leioclada is cut into two halves, the cut rosa sterilis var. leioclada is subjected to a radiation sterilization, the sterilized rosa sterilis var. leioclada is transferred into a fermentation tank, 1-10 parts of edible honey, 80-100 parts of mountain spring water and 1-5 parts of fermenting micro-organisms are added, the mixture is subjected to an initial fermentation, and during the period, one stirring is conducted once a day; and after a still fermentation, the initially fermented products and the stand fermented products are mixed, the mixture is subjected to the still and closed fermentation, the temperature of a fermentation barrel is kept, the mixture is subjected to a natural fermentation, and the fermented mixture is filtered to obtain rosa sterilis var. leioclada enzyme fermented liquid. During the preparation process, the nutrients of the rosa sterilis var. leioclada enzyme raw materials are not lost or destroyed, so that the nutritional and health-care values of the prepared rosa sterilis var. leioclada enzymes are significantly improved. The rosa sterilis var. leioclada enzymes are simple in preparation technology, controllable in preparation processes, and stable in quality, can be stored at room temperature, are suitable for a large-scale production, and have good market prospects.

The invention relates to a fresh-keeping flex-can of red beets and a preparation method thereof. All the recent canned red beets in the world adopt glass or iron cans, which are produced by high-temperature sterilization technology. The invention aims to solve the problems that the red beets are no longer fresh and become soft. The invention adopts non-high-temperature sterilization technology, such as radiation sterilization method, microwave sterilization method, super-high-pressure sterilization method, intense magnetic field sterilization method, ultrasonic sterilization method, chitosan sterilization method, antibiotic enzyme sterilization method and the like, to produce vacuum flex-cans with complex-film. Fresh flex-canned red beets not only are fresh, spicy, crisp and soft which maintain taste, quality and nutrition of food and overcome the disadvantages of high-temperature sterilization, but also have small sizes and light weight, thus reducing costs of transportation and warehousing and increasing additional values.