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Medicament for treating cyclomastopathy and hyperprolactinemia and preparation method of medicament

A technology for hyperprolactinemia and mammary gland hyperplasia, which is applied in the field of medicine to achieve the effects of reducing the level of model prolactin, low toxicity and side effects, and improving the degree of breast tissue hyperplasia

Inactive Publication Date: 2012-10-10
吴金虎 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no medicine to treat these two diseases simultaneously in this field, and to achieve better results

Method used

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  • Medicament for treating cyclomastopathy and hyperprolactinemia and preparation method of medicament
  • Medicament for treating cyclomastopathy and hyperprolactinemia and preparation method of medicament
  • Medicament for treating cyclomastopathy and hyperprolactinemia and preparation method of medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Raw malt 600g Prunella vulgaris 100g Scrophulariaceae 30g Fritillaria 30g

[0048] Salvia 30g Turmeric 30g White Mustard Seed 20g Oyster 20g

[0049] Shan Arrowhead 20g Light Kelp 20g

[0050] Take the above 10 medicinal materials, add water to extract twice, add 5400g water for the first time, extract for 1 hour, add 5400g water for the second time, extract for 1 hour; combine the extracts, concentrate to an extract with a relative density of 1.15 at 80°C, Add ethanol until the volume percentage concentration of alcohol content is 40%, stir evenly, let stand for 8 hours, filter, and concentrate the filtrate to an extract with a relative density of 1.15 at 80°C to obtain the active ingredient.

Embodiment 2

[0052] Raw malt 2000g Prunella vulgaris 600g Scrophulariaceae 200g Fritillaria 200g

[0053] Salvia 200g Turmeric 200g White Mustard Seed 150g Oyster 150g

[0054] Shan Arrowhead 150g Light Kelp 150g

[0055] Take the above 10 herbs, add water to extract twice, add 48000g water for the first time, extract for 2 hours, add 48000g water for the second time, extract for 2 hours; combine the extracts, concentrate to an extract with a relative density of 1.30 at 80°C, Add ethanol until the volume percentage concentration of alcohol content is 70%, stir evenly, let stand for 12 hours, filter, and concentrate the filtrate to an extract with a relative density of 1.30 at 80°C to obtain the active ingredient.

Embodiment 3

[0057] The active ingredient is mixed with an appropriate amount of sucrose, made into granules, and dried to obtain the granules of the present invention.

[0058] Raw malt 800g Prunella vulgaris 200g Scrophulariaceae 50g Fritillaria 50g

[0059] Danshen 50g Turmeric 50g White mustard seed 30g Oyster 30g

[0060] Shan Arrowhead 30g Light Kelp 30g

[0061] Take the above 10 medicinal materials, add water to extract twice, add 13200g water for the first time, extract for 2 hours, add 12000g water for the second time, extract for 3 hours; combine the extracts, concentrate to an extract with a relative density of 1.20 at 80°C, Add ethanol until the volume percentage concentration of alcohol content is 70%, stir evenly, let stand for 32 hours, filter, and concentrate the filtrate to an extract with a relative density of 1.25 at 80°C to obtain the active ingredient.

[0062] The active ingredient is mixed with an appropriate amount of sucrose and preservatives, and water is added...

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Abstract

The invention discloses a medicament for treating cyclomastopathy and hyperprolactinemia and the preparation method of the medicament. The medicament is prepared by a traditional medicament process based on green malt, selfheal, radix scrophulariae, fritillary bulb, salviae miltiorrhizae, radix curcumae, semen brassicae, concha ostreae, rhizoma pleionis and herba laminariae as main ingredients. The process is scientific and reasonable, various preparations can be prepared. The medicament has the characteristics of accurate effects and low toxic and side effects in the aspects of treating cyclomastopathy and hyperprolactinemia, and has good application prospects.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for treating mammary gland hyperplasia and hyperprolactinemia and a preparation method thereof. [0002] Background technique [0003] Hyperprolactinemia is a common hypothalamic-pituitary-gonadal axis disorder, which is caused by a variety of factors that cause excessive secretion of prolactin (>25ng / ml) by eosinophils in the anterior pituitary gland, most of which are The onset in women is clinically manifested as galactorrhea, amenorrhea, oligomenorrhea, and infertility. Clinically, most of the medicines for treating hyperprolactinemia are Chinese patent medicines, which are mainly used to soothe the liver and relieve depression, nourish yin and tonify the kidney, promote qi and resolve phlegm, and break blood stasis to stimulate menstruation. [0004] Mammary gland hyperplasia, also known as breast dysplasia, is caused by adverse mental stimulation, etc., which lead to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P15/14A61P5/08
Inventor 吴金虎陈永刚王雄
Owner 吴金虎
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