Flos chrysanthemi indici effective ingredient and application thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
An effective part, the technology of wild chrysanthemum, applied in the field of biomedicine
Inactive Publication Date: 2012-10-24
ZHENGZHOU UNIV
View PDF3 Cites 6 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
However, we have found through research that the alcohol extract of wild chrysanthemum has a more significant effect of inhibiting hepatitis B virus, and by optimizin
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0017] The effective parts of the wild chrysanthemum of the present invention are extracted by following steps:
[0018] 1) Take wild chrysanthemum, add 5 times the weight of 90% ethanol to extract three times, combine the extracts, filter and concentrate the filtrate to extract;
[0019] 2) Take the extract and add water to make a suspension, add the extract to extract three times, the extract uses petroleum ether-ethyl acetate, the volume ratio is 40:1, after three extractions, combine and recover the solvent under reduced pressure to obtain the effective part .
Embodiment 2
[0021] The effective parts of the wild chrysanthemum of the present invention are extracted by following steps:
[0022] 1) Take wild chrysanthemum, add 8 times the weight of 75% ethanol to extract three times, combine the extracts, filter and concentrate the filtrate to extract;
[0023] 2) Take the extract and add water to make a suspension, add the extract to extract three times, the extract uses petroleum ether-ethyl acetate-ethanol, the volume ratio is 30:3:0.5, after three extractions, combine and recover the solvent under reduced pressure, That is, the effective part is obtained.
Embodiment 3
[0025] The effective parts of the wild chrysanthemum of the present invention are extracted by following steps:
[0026] 1) Take wild chrysanthemum, add 10 times the weight of 60% ethanol to extract three times, combine the extracts, filter and concentrate the filtrate to extract;
[0027] 2) Take the extract and add water to make a suspension, add the extract to extract five times, the extract uses petroleum ether-ethyl acetate-ethanol, the volume ratio is 10:5:1, and after five extractions, combine and recover under reduced pressure Solvent, that is, to obtain the effective site.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses a flos chrysanthemi indici effective ingredient, which is extracted by a method comprising the following steps of: 1) taking flos chrysanthemi indici, adding 60-90% ethanol which is 5-10 times of the weight of the flos chrysanthemi indici to extract, filtering the extracting solution, and concentrating the filtrate into extract; and 2) adding water into the extract to prepare suspension, adding extract liquor to extract, and recovering the extract liquor to obtain the flos chrysanthemi indici effective ingredient. Experiments show that the flos chrysanthemi indici effective ingredient can more obviously inhibit hepatitis B virus, can also inhibit the glutamic-oxalacetic transaminease (AST) and glutamic-pyruvic transaminease (ALT) indexes of liver serum of the damaged liver, can reduce the tumor necrosis factor (TNF) content, liver indexes and malondialdehyde content of the liver serum of the damaged liver, and has good liver protection function. The flos chrysanthemi indici effective ingredient can be used as the active ingredient, and can be prepared into anti-hepatitis B virus medicaments or compositions with the liver protection function, such as food, drinks, health care products, drugs and the like, and the medicaments or compositions can be prepared into tablet, capsule, powder, injections and any other medically acceptable formulations.
Description
technical field [0001] The invention relates to an effective part of wild chrysanthemum flower for anti-hepatitis B virus and liver protection, as well as the application of the effective part, and belongs to the technical field of biomedicine. Background technique [0002] Hepatitis B is an infectious liver disease caused by the continuous replication of hepatitis B virus (HBV). my country is a big country with "hepatitis B", and there are more than 120 million hepatitis B carriers. The mortality rate of liver cirrhosis and liver cancer caused by hepatitis B ranks fifth in my country, and is called the "silent killer". Hepatitis still lacks effective means of control and a thorough solution, and there is no specific drug. Therefore, the research and development of effective drugs for treating hepatitis B has great social and practical significance. Traditional Chinese medicine has become the focus and hot spot of international attention because of its obvious overall effect...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more