Compound detoxifying agent for treating locoweed poisoning of livestock and preparation method of agent

A technology of locopoisoning and antidote, which is applied in antidote, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as heavy workload, inconvenient operation, and poor safety of raw material composition ratio, etc., to achieve Facilitate production, remove intestinal toxins, and save breeding costs

Inactive Publication Date: 2014-01-01
TIBET ACAD OF AGRI & ANIMAL HUSBANDRY SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In order to overcome the deficiencies in the above-mentioned prior art, the present invention provides a compound detoxification liquid for treating locoweed poisoning in livestock and a preparation method thereof. Inconvenient operation and heavy workload

Method used

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  • Compound detoxifying agent for treating locoweed poisoning of livestock and preparation method of agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A compound antidote lotion for treating animal loco-weed poisoning is prepared by dissolving 1000 parts of sterilized water in an antidote combined according to the following weight ratio, and the composition of the antidote is:

[0046] Yeast mannan 0.35-0.45 grams,

[0047] L-rhamnose 0.85-0.95 grams,

[0048] 3.5-4.5 grams of magnesium sulfate,

[0049] Sodium orthophosphate 8.5-9.5 g

[0050] The preparation method of the compound detoxification liquid for treating livestock locoweed poisoning includes the following steps:

[0051] ①Preparation of raw materials and quality ratio composition: yeast mannan 0.35-0.45g, L-rhamnose 0.85-0.95g, magnesium sulfate 3.5-4.5g, sodium orthophosphate 8.5-9.5g,

[0052] Sterilized water: 1000 grams (1 liter).

[0053] ②Dissolution: Dissolve the yeast mannan, L-rhamnose, magnesium sulfate, and sodium orthophosphate prepared in step ① in sterile water, stir with a glass rod to fully dissolve, and adjust the pH value with an acid-base titrator ...

Embodiment 2

[0057] A compound antidote lotion for treating animal loco-weed poisoning is prepared by dissolving 1000 parts of sterilized water in an antidote combined according to the following weight ratio, and the composition of the antidote is:

[0058] Yeast mannan 0.25 grams,

[0059] 0.8 grams of L-rhamnose,

[0060] Magnesium sulfate 3 grams,

[0061] 8 grams of sodium orthophosphate,

[0062] The preparation method of the compound detoxification liquid for treating livestock locoweed poisoning includes the following steps:

[0063] ①Preparation of raw materials and quality composition: 0.25 g yeast mannan, 0.8 g L-rhamnose, 3 g magnesium sulfate, 8 g sodium orthophosphate, sterilized water: 1000 g (1 liter).

[0064] ②Dissolution: Dissolve the yeast mannan, L-rhamnose, magnesium sulfate, and sodium orthophosphate prepared in step ① in sterile water, stir with a glass rod to fully dissolve, and adjust the pH value with an acid-base titrator To 6.9;

[0065] ③ Dispense and seal. Use autoclaved ...

Embodiment 3

[0067] A compound antidote liquid for treating animal loco-weed poisoning is prepared by dissolving 1000 parts of sterilized water in an antidote combined according to the following weight ratio, and the composition of the antidote is:

[0068] Yeast mannan 0.5 g,

[0069] 1 g of L-rhamnose,

[0070] 5 grams of magnesium sulfate,

[0071] 10 grams of sodium orthophosphate,

[0072] The preparation method of the compound detoxification liquid for treating livestock locoweed poisoning includes the following steps:

[0073] ①Preparation of raw materials and quality ratio composition: yeast mannan 0.5 g, L-rhamnose 1 g, magnesium sulfate 5 g, sodium orthophosphate 10 g, sterilized water: 1000 g (1 liter).

[0074] ②Dissolve the yeast mannan, L-rhamnose, magnesium sulfate, and sodium orthophosphate prepared in step ① in a sterilized ultrapure aqueous solution (the sterilized ultrapure water is the purified water, and then Autoclave into ultra-pure sterilized water), stir with a glass rod to f...

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Abstract

The invention relates to a compound detoxifying agent for treating locoweed poisoning of livestock and a preparation method of the agent. The compound detoxifying agent is prepared by dissolving an antidote into 1000 parts of sterilization water, and the antidote is prepared from the following components in part by weight: 0.25-0.5 part of yeast mannan, 0.8-1 part of L-rhamnose, 3-5 parts of magnesium sulfate and 8-10 parts of sodium orthophosphate. The compound detoxifying agent for treating locoweed poisoning of the livestock with the formula provided by the invention has definite components, is proven to have no toxic and side effect of teratogenesis, mutagenesis, carcinogenesis and the like by safety toxicology experiments, and is safe and reliable when being applied to production.

Description

technical field [0001] The invention relates to an antidote for treating locoweed poisoning in livestock, in particular to a compound antidote liquid and a preparation method thereof. Background technique [0002] "Locoweed" (Locoweed) is Oxytropis genus ( Oxytropis DC.) and Astragalus ( Astragalus L .) is a general term for poisonous plants, which are the most serious poisonous weeds that endanger grassland animal husbandry in the world. The annual loss in western Tibet reaches more than 100 million yuan, and the annual loss in Ngari County alone reaches more than 40 million yuan. Yuan, many herdsmen became extinct households, and their lives were extremely difficult. More than 2,000 species have been discovered so far. Locoweeds in my country are mainly distributed in western pastoral areas such as Qinghai, Tibet, Gansu, Ningxia, Inner Mongolia, Shaanxi and Xinjiang. [0003] Local livestock generally do not take the initiative to feed on locograss, and only eat whe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/42A61K31/715A61P39/02A61K33/04A61K31/7004
Inventor 次仁多吉王保海刘建枝梁剑平郝宝成杨贤鹏王学红陶蕾王敬龙夏晨阳郭文柱郭志廷刘宇尚若锋陈慧权晓娣
Owner TIBET ACAD OF AGRI & ANIMAL HUSBANDRY SCI
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