Traditional Chinese medicine monomer combination capable of resisting oxidation and improving eyeground blood circulation
A monomer composition and anti-oxidation technology, which can be used in drug combinations, medical preparations containing active ingredients, anti-toxins, etc., and can solve the problem of BBB permeability reduction and other issues
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[0020] The above and other technical features and advantages of the present invention will be described in more detail below in conjunction with examples and test data.
[0021]The present invention uses the diabetic rat (Wista) model to feed the diabetic rats with the four main monomer components of the traditional Chinese medicine "Siwu Decoction" for 12 weeks, and observes its influence on malondialdehyde (MDA) in the retinal tissue , using the orthogonal experiment to screen out the optimal dose of the traditional Chinese medicine monomer component prescription, and using the above optimal prescription to raise the diabetic rats again for 12 weeks, then observe the retinal tissue with a perspective electron microscope, mainly to observe the structure of visual cells and the ultrastructure of retinal capillaries Variety. In this study, the optimal ratio of ligustrazine=80mg / kg / d, catalpol=7mg / kg / d, ferulic acid=40mg / kg / d, paeoniflorin=100mg / kg / d was obtained through the dia...
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