Natural medicine composition as well as preparation method and application thereof

A technology of natural medicines and compositions, applied in the directions of drug combinations, pharmaceutical formulations, antitumor drugs, etc., to achieve the effects of convenience, obvious synergies, and high industrial practicability

Inactive Publication Date: 2014-03-26
张宗升
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Chemotherapy-related diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but there is no Chinese patent medicine that can relieve diarrhea in anti-cancer chemotherapy

Method used

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  • Natural medicine composition as well as preparation method and application thereof

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Comparison scheme
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Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of concentrated extract from water decoction of Burnet longum longum

[0037] According to the compatibility ratio of 1-4:1, take Burnet and Piper longum, soak in distilled water, heat and decoct, filter, add distilled water to the medicine dregs, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate, and supernatant Membrane filtration, drying under reduced pressure, that is.

[0038] (2) Preparation of total saponins from Burnet burnet

[0039] The dried Burnet medicinal material is crushed, soaked in 70% ethanol overnight, heated and refluxed 3 times, and the extracts are combined to recover the ethanol extract, the ethanol extract is dissolved in water, extracted 3 times with an equal volume of n-butanol, the solvent is recovered under reduced pressure, and vacuum dried. have to.

[0040] (3) Preparation of ethanol extract of Piper longum

[0041] Take longum ...

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Abstract

The invention relates to a natural medicine composition as well as a preparation method and application thereof. The natural medicine composition comprises a sanguisorba officinalis and fructus piperis longi water decoction concentration extract, sanguisorba officinalis total saponins, a fructus piperis longi ethanol extract and piperine, wherein the ratio of the sanguisorba officinalis fructus piperis longi water decoction concentration extract to the sanguisorba officinalis total saponins to the fructus piperis longi ethanol extract to the piperine is (1-5):(3-7):(2-6):(4-7). The composition has curative effect on cancer chemotherapy-induced diarrhea.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of concentrated extract of water decoction of longum burnet, total saponins of burnet, ethanol extract of longipinosa and piperine, the natural medicine The preparation method of the composition and the application of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, which can cause diarrhea and other side effects when used alone or in combination. Diarrhea after tumor chemothe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/739A61P1/12A61P35/00A61K36/67A61K31/4525
Inventor 张宗升
Owner 张宗升
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