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Pure component traditional Chinese medicinal formulation for treating functional dyspepsia and preparation method of formulation

A technology for indigestion and component traditional Chinese medicine, which is applied to the digestive system, medical preparations containing active ingredients, drug combinations, etc., and can solve problems such as many side effects, high costs, and easy recurrence.

Inactive Publication Date: 2014-05-07
湖南中医药大学第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are no specific drugs and treatment methods for functional dyspepsia in Western medicine, mainly using gastrointestinal motility drugs, acid-suppressing drugs, radical cure of HP infection, antidepressant and anxiety drugs and psychotherapy and other symptomatic treatments
However, there are defects such as high cost, easy recurrence, and many side effects after long-term use.

Method used

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  • Pure component traditional Chinese medicinal formulation for treating functional dyspepsia and preparation method of formulation
  • Pure component traditional Chinese medicinal formulation for treating functional dyspepsia and preparation method of formulation
  • Pure component traditional Chinese medicinal formulation for treating functional dyspepsia and preparation method of formulation

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Experimental program
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Effect test

Embodiment 1

[0070] Li, female, 35 years old, came to the Department of Gastroenterology, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine on May 21, 2009. Immediately after the first visit, she found: epigastric distension and pain, lack of appetite, belching, ecstasy, red tongue The fur is white and greasy, and the pulse is stringy and slippery. Gastroscopy examination was: chronic superficial gastritis, Hp: (‐). Give 10 parts of Bupleurum bupleuri, 8 parts of Corydalis Corydalis, 10 parts of Radix Paeoniae Alba, 8 parts of Rhizoma Cyperi, 9 parts of Citrus aurantium, 8 parts of Inula, 6 parts of Toosendan, and 15 parts of Atractylodes macrocephala. After the above-mentioned traditional Chinese medicine components are extracted by flash extraction technology, tablets are made. Take this component of traditional Chinese medicine A+B+C+D+E+F (A:B:C:D:E:F=2:1:1:1:2:1). A total of 60 tablets, 3 tablets orally once, 2 times a day.

[0071] The specific prep...

Embodiment 2

[0074] Huang Moumou, male, 46 years old, came to the Department of Gastroenterology, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine on October 12, 2009. Immediately after the first visit, he saw: epigastric distension and pain, belching, hiccups, nausea, red tongue The fur is white and greasy, and the pulse is stringy and slippery. Gastroscopy examination was: chronic superficial gastritis, Hp: (‐). Give 15 parts of Bupleurum, 8 parts of Corydalis Corydalis, 15 parts of Paeoniae Alba, 8 parts of Cyperus Cyperi, 10 parts of Citrus aurantium, 8 parts of Inula, 6 parts of Toosendan, 15 parts of Atractylodes Rhizoma, 10 parts of Jiao Shenqu (in the basic formula without this ingredient). After the above-mentioned traditional Chinese medicine components are extracted by flash extraction technology, tablets are made. Take this component of traditional Chinese medicine A+B+C+D+E+F (A:B:C:D:E:F=2:1:1:1:2:1). A total of 60 tablets, 3 tablets orally...

Embodiment 3

[0078] Chen Moumou, male, 23 years old, came to the Department of Gastroenterology, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine on April 15, 2010. Immediately after the first visit, he found: epigastric distension and pain, lack of appetite, belching, nausea, red tongue The fur is white and greasy, and the pulse is stringy and slippery. Gastroscopy examination was: chronic superficial gastritis, Hp (‐). Give 15 parts of Bupleurum, 8 parts of Corydalis Corydalis, 10 parts of Radix Paeoniae Alba, 10 parts of Cyperus Cyperi, 9 parts of Citrus Aurantium, 8 parts of Inula inula, 10 parts of Toosendan, 15 parts of Atractylodes Rhizome, and 10 parts of Jiao Shenqu. After the above-mentioned traditional Chinese medicine components are extracted by flash extraction technology, tablets are made. Take this component of traditional Chinese medicine A+B+C+D+E+F (A:B:C:D:E:F=2:1:1:1:2:1). A total of 60 tablets, 3 tablets orally once, 2 times a day.

...

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Abstract

The invention relates to a pure component traditional Chinese medicinal formulation for treating functional dyspepsia, which is prepared by taking Radix Bupleuri (Bupleurum chinense and / or Bupleurum scorzonerifolium), Paeonia lactiflora (Radix Paeoniae Alba), Cyperus rotundus, Atractylodes macrocephala, Melia toosendan fruit, Flos Inulae (Inula japonica and / or Inula britannica), Fructus Aurantii Immaturus (Citrus aurantium and / or Citrus sinensis) and Corydalis yanhusuo as a basic prescription, extracting a component A which uses volatile oil as a main ingredient, a component B which uses sesquiterpene lactone as main ingredient, a component C which uses alkaloid as a main ingredient, a component D which uses flavone as a main ingredient, a component E which uses saponin as a main ingredient and a component F which uses polysaccharide as a main ingredient from the basic prescription with a flash extraction technology, wherein the traditional Chinese medicinal formulation comprises the following components in parts by weight: 5-35 parts of the component A, 5-35 parts of the component B, 5-45 parts of component C, D 5-40 parts of the component D , 10-25 parts of the component E, and 5-40 parts of the component F. The traditional Chinese medicinal formulation is used for treating functional dyspepsia which belongs to liver-stomach disharmony in traditional Chinese medicine with symptoms of stomach duct swelling and pain, pain action or pain worse in case of worry, pain relief after belching and intestinal flatus from anus, chest distress, belching, inhibited defecation, thin and white tongue, and wiry pulse.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pure-component traditional Chinese medicine preparation for treating functional dyspepsia and a preparation process. Background technique [0002] Functional dyspepsia (Functional dyspepsia, FD) is a common clinical chronic non-organic gastrointestinal dysfunction disease, mainly manifested as postprandial fullness, early satiety, epigastric pain, epigastric burning sensation, and excludes explanations Organic, systemic, metabolic diseases of the symptoms. The occurrence of FD is mainly related to gastrointestinal motility disorder, increased visceral sensitivity, changes in gastrointestinal hormones and neurotransmitters, autonomic nervous dysfunction, psychosocial and psychological factors, Helicobacter pylori (HP) infection, gastric acid, genetics, etc. Factors are related, and gastrointestinal motility disorder is the main pathophysiological basis of FD. The g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P1/14
Inventor 王小娟郭建生郭璇徐寅罗燕饶文娟
Owner 湖南中医药大学第一附属医院
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