Colorectal polyps plant inhibitor and preparation method

Abstract

The invention discloses a colorectal polyps biological inhibitor. Its raw material formula contains, by weight, phenacetin, poplar bark, Saw palmetto fruit, Cryptolepis sanguinolenta (Lindl.)Schlecter, Armillariella tabescensand woad. When applied to a patient with colorectal polyps, the colorectal polyps plant inhibitor can effectively inhibit growth of colorectal polyps and further make colorectal polyps atrophy and disappear. When applied to high-risk groups with colorectal polyps at low doses, the colorectal polyps plant inhibitor can effectively reduce morbidity of colorectal polyps for an experimental group. Meanwhile, the inhibitor provided by the invention also can effectively inhibit relapse of colorectal polyps after recovery and prevent conversion of colorectal polyps to tumor. Effectiveness of a placebo is excluded out of the above effects. Moreover, obvious toxic or side effect never appears. The inhibitor is of great significance for improving living quality of patients, prolonging lifetime of patients and reducing morbidity and mortality of colorectal cancer.

Description

technical field [0001] The invention relates to the technical field of application of plant medicinal components, in particular to a plant inhibitor of large intestine polyps and a preparation method thereof. Background technique [0002] Colorectal polyps are chronic epithelial raised lesions that occur in the large intestine, accounting for more than 80% of intestinal polyps, most of which are located in the sigmoid colon or rectum, and are more common in solitary cases, with more males than females. The incidence of colorectal polyps increases with age. In 2003, 20,000 people in Beijing underwent physical examination, and it was found that the detection rate of colonoscopic polyps increased with age, and the detection rate reached 40% for those over 50 years old. According to autopsy data, 60 -The proportion of patients aged 80 is 25%-50%. Pathologically, colorectal polyps can be divided into adenomatous polyps, inflammatory polyps, structural neoplastic polyps, and othe...

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Problems solved by technology

In fact, since the pathogenesis of colorectal polyps has not been elucidated, treatment measures targeting the etiology cannot be obtained. The pathological types of colorectal polyps are complex and diverse, and the progress of occurrence and development is different. The treatment measures cannot be unified, and colorectal polyps are prone to canceration and conservative treatment The risk is high, and the current drug treatment of colorectal polyps has not yet achieved ideal results

In view of the above reasons, although the above studies have proved that aspirin can indeed effectively prevent the recurrence of colorectal polyps, it is still far from the goal of its application in the pre-clinical treatment of colorectal polyps

In addition, long-term use of aspirin and its products is prone to serious adverse reactions. Even taking low-dose aspirin enteric-coated tablets daily will significantly increase the probability of gastrointestinal bleeding and induce fatal aspirin asthma

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