34 results about "Sigmoid colon" patented technology

A colonic overtube for maintaining a sigmoid colon in a straightened configuration has a proximal end for location externally of a colon, and a distal end for insertion into a colon. A colonoscope lumen extends through the overtube to facilitate passing the overtube over a colonoscope. The overtube has a convoluted corrugation which extends along the entire length of the overtube from the proximal end to the distal end. The corrugated configuration of the overtube provides the overtube with laterally flexibility so that the overtube may flex substantially without kinking during advancement of the overtube through a colon. A flexible seal, in the form of a tubular silicone sheath of film material, is provided at the distal end of the overtube for sealing between the overtube and a colonoscope extending through the colonoscope lumen. The flexible nature of the seal enables the seal to adapt itself to the size of the colonoscope extending through the colonoscope lumen to achieve a secure, effective seal between the overtube and a colonoscope regardless of the colonoscope size.

A medical instrument used as a sigmoidoscope (1) for internal examination of the rectum and sigmoid colon of a patient. The instrument includes an outer tubular member in the form of a speculum (2) having a forward insertion end (3) and a rearward observation end (4). An inner tapered guide tube (10) is disposed at least partially within the speculum (2). A retractable obturation tube (15) is disposed between the speculum (2) and the inner guide tube (10) for relative movement between a retracted position substantially within the speculum (2) and an extended position in which the obturation tube (15) protrudes longitudinally beyond the forward end (3) of the speculum (2).

Systems and methods for determining whether the data for a growth curve represents or exhibits valid or significant growth. A data set representing a sigmoid or growth-type curve, such as a PCR curve, is processed to determine whether the data exhibits significant or valid growth. A first or a second degree polynomial curve that fits the data is determined, and a statistical significance value for the curve fit is determined. If the significance value exceeds a significance threshold, the data is considered to not represent significant or valid growth. If the data does not represent significant or valid growth, the data set may be discarded. If the significance value does not exceed the significance threshold, the data is considered to represent significant or valid growth. If the data set is determined to represent valid growth, the data is further processed to determine a transition value in the sigmoid or growth curve, such as the end of the baseline region or the elbow value or Ct value of a PCR amplification curve.

A method for inserting an endoscope into the colon of a patient includes providing a generally rigid insert having proximal and distal ends and having a curved channel passing therethrough with a lateral opening at the distal end. The insert is inserted into the patient's rectum so that the distal end is in proximity to the sigmoid flexure of the colon. The endoscope is then passed through the channel and into the sigmoid colon.

A sigmoidoscope (1) adapted for use in conjunction with a removable obturator to facilitate internal examination of the sigmoid colon of a patient. The sigmoidoscope includes a generally tubular speculum (2) having a sidewall defining a forward insertion end (3), a rearward observation end (4) and an internal lumen (5). The lumen (5) defines a substantially unobstructed viewing path between the observation end and the insertion end. Manually operable insufflation means (10) in fluid communication with the lumen of the speculum are provided for insufflation of the sigmoid colon with an insufflation medium. A coupling element (20) has a proximal end (21) for releasable connection to the observation end (4) of the speculum, a distal end (26) adapted for releasable connection to an optical head (30), and an optically transparent observation window (32) effectively isolating the distal end from the proximal end. The coupling element (20) is adapted upon connection to substantially seal the observation end of the speculum and to prevent direct contact between the optical head (30) and the speculum, without visually obstructing the viewing path.

The invention relates to an auxiliary device for colonoscopy, which effectively solves the problems that the prior medical personnel are very inconvenient to press the abdomen, the patient is not fixed in body position in the examination process, the legs often slide off the bed, and the patient is pushed off the table in the process of pressing the abdomen. The technical scheme comprises a left bedplate and a right bedplate, two sets of clamping splints are arranged on the left bedplate and the right bedplate, and the two sets of clamping splints are staggered to assist the patient in realizing lateral lying posture. A left bedplate and a right bedplate are provide with an abdominal pressing device. An abdominal pressing device comprises four pressing pushrods. The four push rods are allslidably matched with the fixing box and the pressing head fixedly arranged at the front end faces the abdomen of the patient, and the positions of the pressing heads at the front end of the four pushrods are consistent with the colon curve, respectively corresponding to the positions of the sigmoid colon, the colon splenic curve, the middle section of the transverse colon, and the colon hepaticcurve of the abdomen. The invention has ingenious structure, strong practicability, and good operation effect.

Disclosed are diagnostic tests helpful in indicating presence of an inflammatory bowel disease (IBD) in a human patient. In one embodiment, the test comprises obtaining a sample of mucosal tissue from the ileum or sigmoid colon of the patient; evaluating sample quality by testing for cadaverine and continuing the diagnostic test if the sample has no detectable cadaverine; testing the cadaverine negative sample for N-acetylated spermine; and correlating a detectable level of N-acetylated spermine in the sample with presence of IBD in the patient. Another, less invasive, method disclosed includes a diagnostic test comprising isolating mononuclear leukocytes from the patient's blood; testing the isolated mononuclear leukocytes for level of spermidine; and correlating a level of spermidine higher than that in mononuclear leukocytes of normal subjects as indicative of an inflammatory bowel disease in the patient.

The invention discloses a universal oral abdominal and gastrointestinal tract image examination development additive. The universal oral abdominal and gastrointestinal tract image examination development additive is prepared from the following components in parts by weight: 30 to 40 parts of high-permeability contrast substance, 40 to 60 parts of expansion substance, 0.2 to 5 parts of defoaming agent, 10 to 30 parts of stabilizing agent, and 0.02 to 5 parts of corrigent, wherein the high-permeability contrast substance is one or two of mannitol or xylitol; the expansion substance is one or multiple of polyvinylpyrrolidone, Arabic gum or xanthan gum; the stabilizing agent is maltodextrin; the corrigent is one or two of lemon essence or stevioside. The invention also discloses a preparation method of the development additive. The universal oral abdominal and gastrointestinal tract image examination development additive is used for the contrasting display of gastrointestinal tracts (stomach, duodenum and jejunum), rectum and sigmoid colon (enema) during the B-ultrasonic, CT (computed tomography) and magnetic resonance examination, the comparison and description of abdominal solid organs, retroperitoneal structures and diseases, and the elimination of gas and artifacts.

A device and method for treatment of constipation wherein a horizontal bar is positioned a sufficient distance above a toilet that a person using the toilet can passively "semi-hang". The act of passively "semi-hanging" partially removes weight from the perianal area and straightens the torso thereby unfolding the sigmoid colon, increasing the sigmoid-rectal angle and the anorectal angle to facilitate defecation.

The pregressive intestinal canal dilator includes four portions of head end, supporting portion, tail end and operation bar. Said dilator possesses the pregressive increment of dilatation, accurate dilatation, is easy to be operated and controlled, can alleviate patient's suffering, has no need of anesthetization, and does not produce complicating diseases of laceration of intestinal wal, bleeding and intestinal fistula.

A device and method for treatment of constipation wherein a horizontal bar is positioned a sufficient distance above a toilet that a person using the toilet can passively "semi-hang". The act of passively "semi-hanging" partially removes weight from the perianal area and straightens the torso thereby unfolding the sigmoid colon, increasing the sigmoid-rectal angle and the anorectal angle to facilitate defecation.

In the current sigmoid colon and rectum partial resection, the conventional method finishes colorectal anastomosis by inserting a circular anastomat through an anus; the circular anastomat can be smoothly inserted just by fully expanding the sigmoid colon and rectum cavity at the remote end of a smoothing anastomotic stoma before anastomosis; and when the anastomosis part exceeds the anus by 15cm to the sigmoid colon section, because the enteric cavity is astringent, the circular anastomat with longer specification is more difficult to place, and the increase of the factor of operative complication risks is easy to cause in the placing process, a special machine needs to be designed for realizing the full expansion and smoothing of the sigmoid colon and the rectum. The invention provides the sigmoid colon expanding bar which can bring enough lubricant into the sigmoid colon and rectum cavity and fully expand the enteric cavity to solve the clinic problems.

A portable digital rectosigmoidoscope single-handed, digital intestinal endoscope, used by suitably trained healthcare workers to digitally view the anus, rectum and distal sigmoid colon in people with anorectal symptoms at point of care.

The present invention relates to a method and apparatus for treating fecal incontinence. A smooth muscle sphincter is implanted about the distal part of the large intestine in the region of internal anal sphincter or the anal canal, the rectum or the sigmoid colon. The smooth muscle sphincter is electrically stimulated by a stimulator device, in order to contract the smooth muscle sphincter and maintain continence. Stimulation is ceased or varied in order to allow the smooth muscle sphincter to relax and the patient to defecate.

The present invention lies within the field of personalised medicine. More particular the invention relates to biomarkers useful for predicting treatment efficacy and prognosis in cancer patients. Thus the invention provides microRNAs (miRNAs) which are useful for predicting efficacy of anti-angiogenic treatment. In particular, miR-664 for the prediction of response to bevacizumab in colorectal cancer of sigmoid colon or rectum.

The invention provides compositions, kits, and methods for inducing growth arrest, differentiation, or senescence of cancer cells that express thymine DNA glycosylase, and treating the cancer accordingly. The methods comprise inhibiting expression or biologic activity of thymine DNA glycosylase in cancer cells. Inhibition of thymine DNA glycosylase in cancer cells may induce the cells to revert to a healthy, non-cancerous phenotype and / or may induce the cells to senesce. Cancer cells include melanoma, lung, prostate, pancreatic, ovarian, brain, colon, recto-sigmoid colon, and breast cancer cells.

The invention provides a traditional-Chinese-medicine preparation for postoperative rehabilitation of sigmoid colon cancer. The traditional-Chinese-medicine preparation adopts radix ginseng rubra, royal jelly, astragalus membranaceus, raphanus sativus, mulberry, water chestnuts, lotus root, human placenta and rhizoma polygonati as monarch and minister medicines to realize the effects of supplementing more vitality, restoring the pulse and relieving depletion, soothing the liver and regulating qi, inhibiting the cancer-cell dispersion and improving the body immunity, adopts shepherdspurse herb, mangnolia officinalis, rhizoma sparganii, poria cocos, curcuma zedoary, flos sophorae, dianthus superbus, cortex ailanthi, nutgall, glabrous sarcandra glabrous herb and pawpaw to enhance the effects of the monarch and minister medicines and achieve the effects of benefiting the stomach and moistening the intestines, activating blood and stopping bleeding, clearing heat and promoting diuesis, purging fire and removing toxicity and enhancing the appetite of patients. The traditional-Chinese-medicine preparation provided by the invention has the advantages that after the medicines are combined, better effects for improving the symptoms of postoperative patients, relieving or suppressing general reaction, protecting the functions of all organ systems, improving the effective rate for treating the sigmoid colon cancer and reducing the death rate of the patients are achieved.

The invention provides a colon sigmoideum targeting empty capsule. The colon sigmoideum targeting empty capsule comprises a capsule wall material made from gelatin or vegetable gelatin and a coating layer outside the capsule wall material and is characterized in that the coating layer is ethyecellulose, ferric oxide is contained in the capsule wall material, the colon sigmoideum targeting empty capsule comprises the following components in percentage by weight: 65%-75% of gelatin or vegetable glue, 20-30% of the ethyecellulose, and 3-5% of the ferric oxide. The colon sigmoideum targeting empty capsule does not disintegrate within two hours in gastric juice with the pH value of 2, cannot dissolve or disintegrate within 3 hours in intestinal juice with the pH value of 6.8, does not disintegrate within 1 hour in intestinal juice with the pH value of 7.8, disintegrates within 30 minutes in colon sigmoideum juice with the pH value of 8.0 and can rapidly reach a colon sigmoideum part under the guidance of an external magnetic field.

The invention discloses a colonic multifunctional treatment device comprising an anal dilation device, a guide wire, a rectal catheter, a sigmoid colon catheter, a descending colon catheter and a transverse colon catheter. According to the device, colorectal multiple symptoms are treated according to colorectal anatomical characteristics, a colonic multifunctional treatment catheter and a series of catheters used with the colonic multifunctional treatment catheter in a matching manner are designed, optional positions of the colon can be reached by manual placing the treatment catheter at bedsides, the device is convenient and rapid to use and safe and reliable, and diagnosis and treatment purposes of pressure releasing and exhausting, drug injection, and pressure measurement can be achieved accordingly.

The invention provides a colon sigmoideum targeting empty capsule. The colon sigmoideum targeting empty capsule comprises a capsule wall material made from gelatin or vegetable gelatin and a coating layer outside the capsule wall material and is characterized in that the coating layer is ethyecellulose, ferric oxide is contained in the capsule wall material, the colon sigmoideum targeting empty capsule comprises the following components in percentage by weight: 65%-75% of gelatin or vegetable glue, 20-30% of the ethyecellulose, and 3-5% of the ferric oxide. The colon sigmoideum targeting empty capsule does not disintegrate within two hours in gastric juice with the pH value of 2, cannot dissolve or disintegrate within 3 hours in intestinal juice with the pH value of 6.8, does not disintegrate within 1 hour in intestinal juice with the pH value of 7.8, disintegrates within 30 minutes in colon sigmoideum juice with the pH value of 8.0 and can rapidly reach a colon sigmoideum part under the guidance of an external magnetic field.

The invention relates to a kidney-shaped elastic rectoscope which is a rectoscope applied to surgery, check, medicine injection and the like of the rectum and the sigmoid flexure. A rectoscope body of a traditional rectoscope is a straight-cylinder-shaped circular tube and made of non-elastic materials, so that when the traditional rectoscope is used, the traditional rectoscope must be fixed by external force and is inconvenient to use. The kidney-shaped elastic rectoscope is made of elastic high-polymer materials. A whole rectoscope body is a kidney-shaped circular tube with the middle portion thin and the two ends thick, the upper portion of the rectoscope body is a long straight-cylinder-shaped circular tube, the middle of the rectoscope body is a thin kidney-shaped circular tube, and the lower portion of the rectoscope body is a short straight-cylinder-shaped tube or a trapezoid circular tube. The rectoscope can be folded and placed in the rectum and after the folded rectoscope is placed in the rectum, the rectoscope can be restored to the kidney-shaped tube through the elasticity and expansion through appropriate external force. The rectum is expanded by the upper portion of the rectoscope, the anus is expanded by the middle portion, and the rectoscope is held and fixed through the anal sphincter, fixation through the external force is not needed, and use is convenient. The kidney-shaped elastic rectoscope is suitable for the processes of endoscopic surgery, taking out of a sample, check, medicine injection and the like conducted for a rectum sigmoid flexure disease or conducted in the anorectum.

The invention relates to a viscera massage method. The viscera massage method comprises the following steps of: A, performing abdomen inspection and palpation; B, allowing blood to pass through the uterus; C, pressing the Lanmen acupoint and the Ren meridians; D, reversely kneading the liver region to the appendix region from top to bottom; E, pressing various acupoints of the Ren meridians, and rubbing the Shenque acupoint; F, inversely rubbing agglomeration in the spleen region, smoothly rubbing to tonify the spleen, and inversely rubbing the sigmoid colon region from top to bottom; G, carding rims of ribs, and raising and pressing stomach meridians; H, lifting and gathering the Belt vessle and proceeding belly Eight Diagrams; I, improving viscera qi by tremor; J, pressing the Tiantu acupoint; K, opening large and small Tianmen acupoints, and kneading neck meridian tendons and lymph; and L, performing point kneading on the Yingxiang acupoint, and massaging hands to recover the power. In the massage process, no tool is needed, all that is needed is to practice various power exerting skills and manipulation functions in a stepping mode, operation is conducted according to the viscera massage theory, and safety and convenience are achieved.

The invention discloses a method for treating congenital nonvagina by improved sigmoid colon vaginoplasty, which is characterized by comprising the following operation steps: S1, preoperative preparation: preparing intestinal tracts of patients in three days before the operation by using metronidazole for oral administration, preparing full intestinal tracts by using fluid in one day before the operation, and cleaning and enema before and after the operation and in the morning of the same day of the operation; and 200 metronidazole liquid is used for retention enema. According to the method, through preoperative preparation, a measurement method of intestinal canal cutting length, intestinal canal cutting, vaginal cavity formation, intestinal canal underneath arrangement and fixation, and postoperative management, a treatment method of too short colon sigmoid mesangial and a reconstructed vagina peculiar smell prevention treatment are matched, and due to the fact that the anatomical part where the colon sigmoid is located is good for dissection, the colon sigmoid is loose enough when used in the operation; a plurality of bent blood vessels are supplied from the submesenteric artery, so that a section of tissue with proper length and rich in blood supply can be cut out, thus to function like a normal vagina, and the secretion volume of the intestinal canal is moderate, so that the perineal skin cannot be wetted.

The invention is directed to a device (1) for sealingly protective and at the same time stool-discharging tamponade of a circular anastomosis of two ends of the large intestine, as occur for example in the surgical resection of a rectal carcinoma, wherein a thin-walled balloon body (5) is placed in the region of the anastomosis, and the balloon (5), providing a tamponade, is filled with a filling medium in such a way that the lowest possible pressure necessary for the sealing tamponade of the anastomosed portion of the intestine can be maintained continuously, and, even in the event of a peristaltic contraction of the rectosigmoid colon, the pressure predefined by the user is maintained as constant as possible, wherein sufficiently high volumetric flows of the pressurizing medium supplied to and removed from the balloon (5) are achieved, such that the sealing contact between the balloon (5) and the intestinal wall is maintained in all segments of the balloon body in the course of a peristaltic contraction wave running from the sigmoid to the anus.

The invention discloses an auxiliary device used for anal tube gas exhaust. The auxiliary device comprises a negative pressure attraction part and an intestinal tract movement acceleration part, wherein the negative pressure attraction part comprises a first bottle body; the bottle mouth of the first bottle body is sealed through a first bottle cap; a first pipeline is installed on the first bottle cap in a penetration way; the first end of the first pipeline is positioned above the first bottle body; the second end of the first pipeline is connected to the first end hole of a tee joint; the second end hole of the tee joint is connected to the second end of an anal tube; the tee joint can selectively communicate with the first end hole and the second end hole or the second end hole and a third end hole according to requirements; the first end of the anal tube is used for being inserted into the rectum of a subject; an intestinal tract movement acceleration part comprises an abdominal belt body, wherein one side, which faces the abdomen of the subject, of the abdominal belt body forms a plurality of independent first air bags; the first air bags are subjected to air inflation in sequence according to an extension path of the ascending colon, the transverse colon, the descending colon, the sigmoid colon and the rectum, and an air inflation state is kept; and the intestinal tractmovement acceleration part and the negative pressure attraction part can simultaneously work.

The invention relates to a traditional Chinese medicine sigmoid colon drip preparation for treating infantile exogenous fever as well as a preparation method and application thereof. The preparation is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 4-8 parts of radix puerariae, 4-8 parts of radix bupleuri, 8-12 parts of radix scutellariae, 12-18 parts of gypsum, 2-4 parts of rheum officinale, 4-8 parts of fructus gardeniae, 4-8 parts of rhizoma curcumae, 8-12 parts of folium chimonanthinitentis, 10-12 parts of fructus citrus sarcodactylis, 4-6 parts of cicada slough, and 2-4 parts of radix glycyrrhizae. The traditional Chinese medicine sigmoid colon drip preparation for treating the infantile exogenous fever, provided by the invention, has the characteristics of 'quick response, good treatment effect, low possibility of rebounding of body temperature, obvious symptom relief, small untoward effect' and the like in treatment of the infantile exogenous fever, and has a better effect of treating wind-heat stagnant type infantile exogenous fever.

The invention relates to the technical field of medical equipment, and discloses a fecal drainage device of retention enema type. The device comprises a drainage corrugated pipe, an enema device and acollection device. One end of the drainage corrugated pipe is fixedly sleeved with a cannula, and one end of the cannula far away from the drainage corrugated pipe is fixedly sleeved with the enema device. In the fecal drainage device of retention enema type, an enema catheter made of silica gel goes deep into sigmoid colon, and continuous irrigation and flushing functions of the sigmoid colon and the rectum position thereof are achieved by a design of six side holes; in addition, a high-strength film is naturally extruded by the anus to achieve retention enema without external pressure, so as to ensure the full effect of drugs on the sigmoid colon and the rectum position thereof; and the fecal drainage device of retention enema type solves the problem that the existing enema device doesnot have the function of retention enema, so that some patients with low colon diseases such as ulcerative colitis, chronic non-specific colitis, and rectal diseases cannot be treated.

The invention relates to a diagnostic marker, in particular to a biological marker for detecting colorectal cancer and application thereof. Experiment and study find that a PAPPA (pregnancy-related plasma protein A) gene has obvious difference between the mRNA expression levels in colorectal adenocarcinoma tissues, mucinous colorectal adenocarcinoma tissues, cecal adenocarcinoma tissues, sigmoid colorectal carcinoma tissues and rectal adenocarcinoma tissues and the mRNA expression level in the tissues of healthy reference substances; the PAPPA protein expression level in serum of a colorectalcancer patient is significantly higher than the protein expression level in the serum of a normal person. The biological marker has the characteristics that the correlation between the PAPPA and the colorectal cancer is put forward for the first time; experiment proves that the PAPPA can be used for diagnosing the colorectal cancer; the operation is simple, the specificity is high, and the sensitivity is high.

The invention provides an environment-friendly pollution control full-degradable disposable medical device base material and a manufacturing method thereof. The environment-friendly pollution control full-degradable disposable medical device base material is characterized by being prepared from a full-degradable macromolecule main material which is a pure polylactic acid base material with molecular weight equal to or greater than two millions. The full-degradable base material can be used for manufacturing the following disposable medical devices: a disposable cervical dilator, a disposable uterine probe, a disposable uterine curet, a disposable vagina dilator, a disposable intrauterine device extractor, a disposable fallopian tube pick-up hook, a disposable fallopian tube pick-up plate, a disposable cervix uterus biopsy sampler, a disposable umbilical clamp, a disposable tongue depressor, a disposable bite block, a disposable oropharynx air passage, a disposable anaesthetic laryngoscope, a disposable rhinoscope, a disposable otoscope, a disposable anoscope, a disposable rectum, a sigmoid colon biopsy forceps, a disposable nasopharynx biopsy forceps, a purging head of a disposable flusher, a disposable surgical knife handle, a disposable oral cavity impression tray and the like. The used disposable medical devices do not need to be incinerated, can be treated in compost environments and fully degraded by microorganisms, thus achieving the purposes of environmental protection, energy conversation, no environment pollution, safety, health, benefit of mankind and the like.