Radiobiological functional experiment box

Abstract

The invention discloses a radiobiological functional experiment box which comprises a box body and matched fixing supports. The box body comprises a box rear plate structure, a box bottom bin structure, a three-dimensional fixing substrate structure, a sterile sleeve opening structure, a box chamber, box side plates and an incident center point. The matched fixing supports comprise an in-vitro cell experiment fixing support, an insertion piece fixing support, a clamshell type fixing support and a limb end locating type fixing support. Functions of the radiobiological functional experiment box include irradiation, anatomy, injection, temporary rearing and the like, the coverage of use objects is wide, sterile operation and ingenious fixing of irradiated portions can be achieved, and it is guaranteed that experimental subjects keep awake and alive. Multiple animals can be fixed and irradiated at the same time, so that specific operation time of experiments is shortened, and a dose is reduced. The radiobiological functional experiment box is reasonable in design, convenient and safe to operate, environmentally friendly and high in practicality and universality.

Description

technical field [0001] The invention relates to an experimental appliance, in particular to a radiation biology multifunctional experiment box. Background technique [0002] The subject of radiation oncology has developed rapidly in recent years, and the related basic and clinical research has also developed rapidly. Generally, the verification of radiobiological results needs to be confirmed by biological (animal) experiments. The most common is experimental research by establishing tumor animal models. In the experiment, the fixation of the experimental object is a problem, especially the fixation of small animals is a difficult problem. Moreover, the research on bioradiation auxiliary devices at home and abroad has always been a blank. Irradiation experiments on ordinary rats and mice have relatively low requirements on the environment and mouse state. We mostly use more intuitive, primitive, and rough methods. As long as the fixed method can meet the experimental requ...

AI Technical Summary

Problems solved by technology

[0004] 1. The experimental operation is complicated, laborious and time-consuming: the process of fixing mice is complicated, and the cell multi-plate comparison experiment needs to be irradiated in batches, and the process steps are numerous;

[0005] 2. Low versatility and serious waste of resources: mice of different ages need to use different test tubes or order different lead boxes, and the production cost is high;

[0006] 3. Insufficient fixation: the mouse may move and break free, the cell culture vessel is easy to overturn during the transfer process, and the culture vessel may slide and shift during irradiation;

[0007] 4. The layout of the irradiation field is not accurate enough: according to the fixed position, the size needs to be adjusted at any time, and it is time-consuming and complicated, which increases human error;

[0008] 5. Poor sterility: directly exposed to the outside air during transfer and irradiation, which cannot meet the basic requirements of the experiment;

[0009] 6. The survival rate of rats is low, and the mechanical force is difficult to control when the rats are immobilized, which can easily injure the rat body, and it is easy to die when exposed to the external environment or die from hypoxia and suffocation;

[0010] 7. Unable to meet environmental protection requirements: the high production cost of using a large amount of lead blocking, environmental pollution, and frequent use of disinfectant;

[0011] 8. Increased uncertainties: There are many experimental steps, more links that need to be disinfected, poor sterility, cumbersome control steps such as constant temperature, and require caution, which increases the risk factor;

[0012] 9. The protection of normal non-irradiated areas is not good: the irradiation of normal organs is caused by factors such as displacement and field placement

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