A kind of anti-swine foot-and-mouth disease composition, freeze-dried powder, preparation method and application

Abstract

The invention discloses an anti-swine foot-and-mouth disease composition, freeze-dried powder, preparation method and application, and belongs to the technical field of animal feed additives. The composition is composed of the following components in parts by weight: 95-100 parts of anti-swine foot-and-mouth disease egg yolk antibody, and 1-5 parts of anti-swine foot-and-mouth disease transfer factor. The freeze-dried powder is composed of the following components by weight: 95-97 parts of anti-swine foot-and-mouth disease yolk antibody, 1-2 parts of anti-swine foot-and-mouth disease transfer factor, 0.2-0.3 parts of inactivator, 0.01-0.02 parts of preservative, heat-resistant 2.05-3.6 parts of freeze-dried protective agent; it has the advantages of reducing storage conditions, prolonging storage time, high antibody titer, and good biological activity. The combined use of anti-foot-and-mouth disease transfer factor and anti-foot-and-mouth disease egg yolk antibody has the effect of preventing and treating porcine foot-and-mouth disease. Improve pig immunity and survival rate, easy to use and low cost.

Description

technical field [0001] The invention specifically relates to an anti-foot-and-mouth disease composition for a feed additive, and also relates to an anti-foot-and-mouth disease freeze-dried powder as well as a preparation method and application thereof, belonging to the technical field of animal feed additives. Background technique [0002] Foot-and-mouth disease (FMD) is an infectious disease that is caused by foot-and-mouth disease virus (FMDV) and is characterized by blisters on the mouth and hooves of sick animals. Foot-and-mouth disease is characterized by acute onset and rapid spread. In addition to being transmitted through solid objects contaminated by infected animals, it can also be transmitted over long distances through the air in the form of aerosols. The morbidity rate can reach 100%. Piglets often die suddenly without symptoms, and the mortality rate can reach 100% when severe. Once the disease occurs, if the early eradication is delayed, the epidemic situati...

AI Technical Summary

Problems solved by technology

Once the disease occurs, if the early eradication is delayed, the epidemic will often expand rapidly, resulting in an unmanageable situation, and it is difficult to eradicate

Effective measures to control and exterminate porcine foot-and-mouth disease are to cull diseased pigs and suspected infected pigs, restrict animal movement and meat marketing, thus causing serious economic losses

[0003] The pig industry accounts for a relatively large share in my country's breeding industry. In 2009, only Henan Province produced 4.1032 million tons of pork. From this, it can be deduced that my country's annual meat production demand is quite large, and it is showing a rapid increase trend. However, pig farming There are also various diseases in the pig industry. In recent years, the continuous occurrence of pig foot-and-mouth disease has caused great economic losses to the pig industry.

[0004] At present, people use vaccines to immunize porcine foot-and-mouth disease. The early effect is better, but multiple vaccinations are required, the operation is troublesome, the cost is high, and it is easy to cause stress reactions in livestock and poultry. In addition, the vaccines have strict requirements for storage conditions. Refrigerate at low temperature, and expire at room temperature for a period of time

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