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Activated carbon nanosphere and application thereof to tumor boundary and lymph gland tracing

A technology of nano-microspheres and activated carbon, applied in the field of nanoparticles, can solve problems such as technical difficulties, and achieve the effect of obvious lymphatic tracing effect, remarkable tracing effect and simple method.

Inactive Publication Date: 2014-12-17
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, there are still great technical difficulties in the application of activated carbon as a carrier for tracers.

Method used

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  • Activated carbon nanosphere and application thereof to tumor boundary and lymph gland tracing
  • Activated carbon nanosphere and application thereof to tumor boundary and lymph gland tracing
  • Activated carbon nanosphere and application thereof to tumor boundary and lymph gland tracing

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Embodiment Construction

[0034] The technical solution of the present invention will be described in detail below in conjunction with the accompanying drawings. The embodiments of the present invention are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the invention can be modified or equivalently replaced , without departing from the spirit and scope of the technical solution of the present invention, all of which shall be covered by the claims of the present invention.

[0035] The activated carbon composite nano-microspheres involved in this embodiment are prepared as follows

[0036] First, place the activated carbon in a ball mill to grind, take it out, put it in water and let it stand for two days, take the upper layer suspension, and obtain activated carbon nanospheres wit...

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Abstract

The invention discloses an activated carbon nanosphere which is prepared by taking activated carbon particles with the particle sizes of 10-100nm as carriers, and the surfaces of the activated carbon particles are compounded with an organic dyestuff. The activated carbon nanosphere disclosed by the invention is rather strong in dyeing property, remarkable in tracing effect and capable of remarkably showing a lymph tracing effect for a tested living body within half a hour, realizing multi-mode imaging and directly observing the trace of the nanosphere from tumors, tissues or organs through naked eyes.

Description

technical field [0001] The invention relates to a nano particle, in particular to a composite nano particle prepared with activated carbon as a carrier, and the application of the nano particle in determination of tumor boundaries and lymph node metastasis tracing. Background technique [0002] At present, there are nearly 3 million cancer deaths in my country every year, and surgery is still the first choice and the most effective treatment. However, the postoperative survival rate at home and abroad has remained at a low level. Taking gastric cancer as an example, the postoperative 5-year survival rate is mostly hovering at 20-30%. A big reason is that the lymph nodes were not completely removed during the tumor resection, and the infiltrating tumor cells passed through the lymphatic vessel wall and transferred along the lymphatic vessel with the lymph fluid, causing the patient to relapse or metastasize and die within a short period of time after surgery. [0003] Chines...

Claims

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Application Information

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IPC IPC(8): A61K49/00A61K47/04
Inventor 崔大祥高国孙容瑾邱培宇张英鸽王玉霞
Owner SHANGHAI JIAO TONG UNIV
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