The invention relates to a spreadsheet-based fast customization and integration method for a satellite design system and belongs to the field of design of spacecrafts. The method includes the first step of sorting and summarizing the general flow of designing remote sensing satellites or other types of spacecrafts on the basis of a traditional process expression mode, the second step of conducting mapping to generate a DSM matrix, conducting statistics on DSM items and conducting structured quantitative analysis item by item to obtain a perfect parameter correlation list, and the third step of utilizing the spreadsheet-based middleware technology to achieve storage of a spreadsheet in a database, establishing four modules through existing functions of middleware of the spreadsheet and then achieving fast customization of the spacecraft design system, wherein the four modules are an engineering application module, a DSM modeling module, a project management module and an import and export module. According to the method, the existing spacecraft design process is mapped to generate a DSM, the DSM is stored into the database for maintenance, the Excel spreadsheet is used as a front-end interface, and consequently a foundation is laid for follow-up optimization.