The invention discloses an AES parallel implementation method based on OpenCL. According to the scheme, when an AES performs parallel running on an AMD GPU based on OpenCL, optimum performance can be achieved. The method includes the following steps that first, the number of plaintext/ciphertext and the number of round key groups are determined, and plaintext /ciphertext and round key data are prepared; second, an executing mode of the AES is determined, and preparation is made for writing of a KiReadyThread; third, the KiReadyThread is written; fourth, a master OpenCL program file is written, and preparation is made for execution of an OpenCL program; fifth, program running parameters are set, memory space is allocated, and the program runs; sixth, the encryption and decryption result is acquired, and resources are released. According to the method, in parallel running process of the AES, data are reasonably allocated in a memory and parallel granularity is reasonably selected so that running performance can be improved, and the method can be used for fast encryption and decryption or password cracking machines.