48 results about "Lymph fluid" patented technology

The utility model discloses a breast cancer postoperative affected limb position adjusting device, which belongs to the technical field of medical instruments and comprises a scapular fixing pad and an affected limb adjusting pad, the scapular fixing pad is laid under the back of a patient and connected with the affected limb adjusting pad, and the affected limb adjusting pad can slide relative to the scapular fixing pad to adjust the height of the affected limb adjusting pad. A diseased limb placing cavity is formed in the diseased limb adjusting pad, the width of the diseased limb placing cavity is adjusted according to the height of the diseased limb adjusting pad, when the height of the diseased limb adjusting pad is increased, the width of the diseased limb placing cavity is synchronously increased, and when the height of the diseased limb adjusting pad is reduced, the width of the diseased limb placing cavity is synchronously reduced. The height of the affected limb adjusting pad can be adjusted according to the weight of a patient, meanwhile, the width of the affected limb containing cavity is synchronously adjusted, the hand of the patient is always higher than the elbow, the elbow is higher than the heart, backflow of blood or lymph is facilitated, and the affected limb containing cavity can be used for containing the limbs of the patient all the time.

The invention discloses an electrical stimulation lymphedema rehabilitation device, and relates to the technical field of lymphedema rehabilitation, and the device comprises a housing, and also comprises an electrical stimulation mechanism which is installed at the top of the housing and comprises a plurality of electrode plates; the limb supporting mechanism is installed on the two sides of the shell and comprises a first lantern ring and a second lantern ring; the multi-section massage mechanism is installed in the shell and comprises a plurality of air bags, and one side of each air bag is communicated with an electromagnetic valve; the uniform pressing mechanism is connected with the multi-section massage mechanism and comprises a downward moving anti-sticking mechanism and a translation switching mechanism; the electrical stimulation mechanism further comprises a controller fixed to the top of the shell, and the controller is electrically connected with the multiple electrode slices. By installing the uniform pressing mechanism, uniform massage is achieved, the pressing position of the air bag is changed, the whole limb is pressed uniformly, the pressing strength of all parts of the limb is prevented from being different, the problem that the whole limb is pressed unevenly is effectively solved, and therefore lymph circulation is more efficiently promoted.

The utility model relates to breast nursing technical field especially a breast nursing dredging device, including handle, the surface screw thread connection of handle has the cover cup, the inner chamber of cover cup is provided with the massage head, the inner chamber of cover cup is provided with the adjusting mechanism, the adjusting mechanism includes the massage block, the massage block swing setting is in the inner chamber of cover cup, the surface of massage block is connected with the cannula, the surface of handle is provided with the liquid adding pipe, one end of liquid adding pipe is connected with the connecting pipe, the utility model discloses through the cooperation of massage head, massage block, cannula, liquid adding pipe, connecting pipe, ring pipe, liquid warehouse pipe, driving motor, sliding mouth and ball, is equipped with rolling massage head and sliding mouth, can add the liquid of alleviating automatically in the massage process, utilizes driving motor to drive the ball rolling massage and liquid alleviating combination, can more deeply stimulate breast cell, promotes blood and lymphatic fluid circulation, accelerates the dredging and recovery of breast.

The invention discloses an anastomosis instrument for connecting multiple lymphatic vessels and blood vessels. The anastomosis instrument comprises a blood vessel connecting piece and a plurality of lymphatic connecting tubes. According to the integrated anastomosis instrument, the multiple lymphatic vessels can be connected to the lymphatic connecting tubes respectively through the arrangement of the integrated anastomosis instrument with the multiple lymphatic connecting tubes, and the lymphatic vessels are finally guided into the same vein blood vessel through the through holes; therefore, an efficient connection mode of multiple lymphatic vessels and a single blood vessel is realized, the surgical operation is greatly simplified, the surgical time is shortened, the surgical difficulty is greatly reduced, and the risks of postoperative bleeding, inflammation and vascular stenosis are reduced; in addition, due to the establishment of a plurality of drainage channels, the total drainage efficiency of lymph is effectively improved, and the device is more suitable for clinical conditions with large lymphatic load.

The invention provides a lower limb lymphedema rehabilitation training device which comprises a supporting plate, a first rotating plate is rotatably installed on one side of the supporting plate, a second rotating plate is rotatably installed on the side, away from the supporting plate, of the first rotating plate, and protection assemblies are arranged on the side face of the first rotating plate and the side face of the second rotating plate. A training assembly with adjustable resistance is arranged between the first rotating plate and the supporting plate, and an elastic positioning assembly is arranged between the first rotating plate and the second rotating plate. The lower limb lymphedema rehabilitation training device is used for lower limb training when a patient lies in bed, lymph backflow is assisted by raising legs, rehabilitation treatment of the lower limb lymphedema patient is facilitated, medical staff can adjust the strength of the training device according to the physical quality of the patient in the training process, and the lower limb lymphedema rehabilitation training device is suitable for being used by different staff; meanwhile, the training device can be used for massaging the shanks of the patient, dredging channels and promoting lymph backflow, has ventilation and perspiration functions and is convenient for the patient to use.

A system and method are provided for a body fluid management system for pumping body fluids such as lymph. The body fluid management system may include an implantable pump having: a rotor having a magnetic portion; and inlet and outlet pipes connected to a fluid chamber. The fluid chamber has a volume that can be selectively decreased or increased via the rotor. The rotor is designed to periodically open and close a bend valve at each of the inlet and outlet pipes to allow body fluid to enter the fluid chamber during an inhalation cycle and exit the fluid chamber during an exhalation cycle. The magnetic portion of the rotor can be rotated by an external controller positioned outside the body and near the pump. The external controller may have a magnet magnetically coupled to the rotor to rotate it.

The utility model discloses a novel circumcision anastomat which comprises an inner ring and an outer ring, the inner ring is used for supporting the inner side of a prepuce, the outer ring is composed of a pair of outer ring lock catches which can be mutually locked, a dull knife is arranged on the inner side of each outer ring lock catch, a drainage assembly is arranged on each dull knife, and the outer ring lock catches are buckled on the outer side of the inner ring. The blunt knife extrudes the foreskin tissue on the outer side of the inner ring, the to-be-cut tissue and the reserved tissue are isolated through the arranged inner ring and the locking mechanism, so that the to-be-cut tissue necroses and falls off, then cutting is completed, in addition, tissue fluid is guided out to be away from the isolation belt through the drainage assembly, and it is guaranteed that the position nearby the tissue fluid is kept dry; lymph accumulation and flowing around are avoided, and cross infection is reduced, so that edema is relieved, and healing is faster.

Systems, devices, and methods of connecting two anatomical structures to facilitate fluid communication between the structures may utilize percutaneous and / or endovascular entry routes to the anatomical structures so that they may be positioned proximate to one another and a channel for facilitating fluid communication between them may be formed. In some cases, a first anatomical structure is a vein and a second anatomical structure is a lymph node and, in these instances, the lymph node may be positioned proximate to the vein so that a channel that allows lymphatic fluid to drain into the vein may be formed as a way of treating and / or preventing lymphedema.

The present application relates to the field of biophysics technology, especially to a kind of calculation method for considering the contribution of biological activity to human sensory function.It includes a new type of calculation analysis model for considering the motion of cochlear acoustic function key support structure of biological activity based on physical mechanics principle.The present application deduces the periodic variation of the stiffness of basilar membrane in space and time while coupled with lymphatic fluid motion equation, and is solved.I.e.develop a kind of calculation method for considering the contribution of biological activity to human sensory function, and the correctness of the analytical method is verified by computer numerical simulation.The method established by the present application is easy to operate, feasible, efficient and accurate.

This invention discloses an instrument for connecting lymphatic vessels and blood vessels, comprising a vascular connecting tube, a connecting lumbar tube, and at least one connecting branch tube. The connecting branch tube includes interconnected primary and secondary branches, through which lymph fluid can enter the bloodstream. This instrument enables a stable connection between lymphatic vessels and blood vessels via the instrument itself, rather than relying solely on surgical sutures. This simplifies the surgical procedure, reduces the stringent requirements on the surgeon's skills, significantly reduces the difficulty and risk of the surgery, decreases the incidence of postoperative complications, improves patient recovery speed and treatment effectiveness, and provides a more convenient and reliable connection method, greatly enhancing the convenience, safety, and effectiveness of connecting lymphatic vessels and blood vessels.

This invention relates to a cannulation device and manufacturing method for draining intestinal lymphatic fluid in small animals. The device includes a catheter and a guidewire. The catheter includes an insertion section and a drainage section, the outer and inner diameters of which are smaller than those of the drainage section. The guidewire can be inserted along the catheter, and its outer diameter is smaller than the inner diameter of the insertion section. The insertion tip of the guidewire is blunt and rounded, and the tail end of the guidewire is provided with a handle. By using the cannulation device of this invention, the problems of difficult catheter insertion and significant damage to the mesenteric lymphatic vessels during pretreatment in existing intestinal lymphatic fluid drainage cannulation techniques are solved, reducing the difficulty of surgical operation, shortening the operation time, reducing tissue damage, and improving the success rate of surgery.

The invention relates to the technical field of teaching aids, and discloses a manipulative lymphatic drainage teaching aid for lymphedema and an operation evaluation system.The teaching aid is provided with a sleeve which can be worn on the arm of a student, and the sleeve is provided with an inner layer, a middle layer and an outer layer which are sequentially arranged from inside to outside; the middle layer is provided with a plurality of independent light-emitting units, the light-emitting units can emit light of various colors, and the light-emitting colors are adjustable; each light-emitting unit is connected with a pressure sensor, and each pressure sensor is used for detecting the pressure borne by the corresponding light-emitting unit. The middle layer is further provided with a controller, the controller is connected with the pressure sensors and the light-emitting units, and the controller is used for controlling the light-emitting colors of the corresponding light-emitting units according to the pressure detected by the pressure sensors and a control instruction. The device can simulate lymph and realize the flow of the lymph through pushing, can feed back the pushing strength of a student in real time, can be worn on the student, does not need to take off a coat, and effectively improves the teaching effect of manipulative lymphatic drainage training.

This invention discloses a hair cell protectant based on a ferritin nanoplatform and its application in treating hearing loss, belonging to the field of biomedicine. The ferritin nanoparticles of this invention, loaded with cimicifugin, include ferritin (Fn) as a carrier and cimicifugin (Ci@Fn) loaded within the ferritin. By loading cimicifugin (Ci), an extract of cimicifugin, into ferritin, it is endowed with additional anti-inflammatory and tissue-protective functions, thereby achieving a more precise and effective therapeutic effect. After injection through the round window membrane (RWM) behind the ear, Ci@Fn is transported to the basement membrane along with the flow of perilymph and endolymph, ultimately targeting the inner ear hair cells (HCs). After entering the hair cells, Ci@Fn is taken up and degraded by lysosomes, releasing cimicifugin (Ci), thereby exerting a protective effect on the hair cells.

The invention discloses a knee joint fixing brace and a using method thereof, and belongs to the technical field of medical instruments, the knee joint fixing brace comprises a thigh fixing support and a shank fixing support, air bags are arranged on the inner side walls of the thigh fixing support and the shank fixing support, the air bags are connected with an external pressure pump through air pipelines, and air pressure valves are arranged on the air pipelines; the thigh fixing support and the shank fixing support are connected together through a connecting assembly to form a cylindrical structure, an upper connecting rod is arranged on the outer side wall of the thigh fixing support, a lower connecting rod is arranged on the outer side wall of the shank fixing support, and the upper connecting rod and the lower connecting rod are connected together through a hinge assembly. Gradient pressure changes are applied to limbs, the limbs are regularly inflated and deflated, the effect similar to muscle contraction and relaxation is generated, blood backflow and lymph circulation are promoted, blood supply of local tissue is improved, blood circulation is promoted, edema is relieved, and the risk of lower limb deep vein thrombosis is reduced.

1. Name of the product in this design: Medical colorimeter ruler. 2. Purpose of this design: This design is used to compare the colors of patient drainage fluids, secretions, and excretions, such as the color of blood, vomit, stool, sputum, urine, bile, lymph, and various drainage fluids. 3. The key design features of this product are the combination of pattern and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color. 6. Other situations requiring explanation: This design is a two-dimensional product, and the top view, bottom view, left view, and right view are omitted.

The utility model relates to comfortable pressurizing underwear special for breast cancer postoperation, and aims to solve the problems that breast and armpit areas of a patient after breast cancer operation are insufficiently supported, the pressurizing effect is not ideal, infection is prone to occurring, and the comfort degree is poor. The underwear comprises an underwear main body, chest cushion layers, oxter cushion layers, chest and oxter interlayer grooves, chest and oxter pressurizing cushions, adjusting row buckles and the like. The underwear main body is made of a high-elasticity, breathable and skin-friendly fabric, and an antibacterial and anti-infection material is embedded into the underwear main body; the chest and the oxter cushion layer provide necessary support; the design of the interlayer groove and the pressurizing pad realizes personalized pressurizing bandaging; the row buckles are adjusted to adapt to patients with different body types. In addition, the underwear is further provided with the axilla cushion layers which are arranged in a suitable mode, and the requirement for single-side or double-side mammary gland pressurization is met. By means of the comprehensive design, the postoperative comfort of a patient is effectively improved, lymph backflow is promoted, edema is reduced, wound healing is accelerated, the infection risk is reduced, and comprehensive and effective recovery support is provided for the breast cancer postoperative patient.

1. The name of the design product: vertical dynamic interference electric treatment instrument. 2. The use of the design product: for promoting the backflow of blood and lymph by causing muscle contraction and relaxation through interference current. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

This invention relates to the field of cognitive data processing technology, and more particularly to a method and system for physical stimulation-driven lymphatic circulation and cognitive enhancement. The system includes a physical stimulation frequency impact assessment module, a stimulation mechanical vibration analysis module, a lymphatic circulation vibration calibration module, and a stimulation frequency drive adjustment module. It utilizes pressure and temperature sensors to monitor the corresponding physical stimulation pressure and the surface temperature of the stimulated skin in real time, performing stimulation frequency impact assessment and stimulation mechanical vibration analysis to generate a physical stimulation mechanical vibration effect. It also acquires lymphatic fluid flow velocity and EEG neural activity signals, performing neurocognitive level analysis and vibration response calibration. Simultaneously, it performs lymphatic circulation cognitive regression analysis and stimulation frequency drive adjustment to generate a physical stimulation frequency drive adjustment scheme corresponding to lymphatic circulation cognitive enhancement. This invention can accurately analyze the correlation between physical stimulation and lymphatic circulation and cognitive enhancement.

The utility model relates to a groin pressurizing device. The groin pressurizing device comprises a pressing sandbag and an auxiliary sandbag connected with the pressing sandbag, the auxiliary sandbag is connected with the compression sandbag through a connecting belt, and a fixing assembly used for fixing the connecting belt is arranged on the compression sandbag; the whole pressing sandbag is of a structure with the front pointed and the rear wide, and the width and the thickness of the pressing sandbag from the front end to the rear end are in a gradually-increasing trend. And the compression sandbag is detachably connected with the self-adhesion fuzzing cloth. Compared with the prior art, the groin pressurizing device has the advantages that effective sandbag fixing of a groin postoperative patient can be achieved, a better pressurizing recovery effect is achieved, bleeding, exudation and edema can be reduced, lymph backflow is promoted, and the risk of postoperative complications is reduced.

The application belongs to the technical field of biology, and discloses a system for continuous drainage of mesenteric lymph fluid and application thereof, which comprises a mesenteric lymph vessel catheter for being inserted into a mesenteric lymph vessel to drain mesenteric lymph fluid, a jugular vein catheter for being inserted into a jugular vein, a collector for collecting lymph fluid, and a conscious activity device comprising a quick connection button VAB and a mesenteric lymph fluid collecting tube, wherein the outlet end of the mesenteric lymph fluid collecting tube is in the same height as the inlet end of the mesenteric lymph vessel catheter. The method can realize real-time and long-term collection of lymph fluid under the conditions of free activity, unrestricted diet and water and normal physiological state of rats, can avoid the influence of surgical stress, general anesthesia or animal restriction on experimental results, can reflect the real state of lymph fluid, and can be applied to the fields of research on lymph vessel absorption capacity and functional state and explanation of disease mechanism.

The utility model provides an otolithiasis semicircular canal three-dimensional model, which relates to the technical field of medical models, and comprises a base, a pillar is fixedly connected above the base, the end part of the pillar is rotatably connected with a model arc frame, and the inside of the model arc frame is rotatably connected with a simulation head model through a fulcrum shaft. The simulation semicircular canal model is fixed outside the simulation head model in a popular and easy-to-understand manner, so that the inclination angle of the simulation semicircular canal model is consistent with the inclination angle of the semicircular canal in a human body, understanding of a patient is facilitated, and the simulation semicircular canal model is filled with a glycerin solution for simulating internal lymph in the semicircular canal, so that the simulation head model can be used for simulating the internal lymph in the semicircular canal. Along with the inclination and rotation of the simulation head model, the movement track and path of the otolith crystal model in the simulation semicircular canal model in the internal lymph can be observed, and the problem that a patient cannot clearly understand the treatment process of otolithiasis due to the fact that the patient cannot easily understand the structure of the patient and the relation between the angle of the canal body model and the angle of the head of the human body is solved.

The application discloses a preparation method of silkworm blood lymph fluid with inhibited melanization reaction and low endotoxin, which comprises the following steps: low endotoxin silkworm variety selection, silkworm body disinfection and impurity removal, silkworm body low-temperature anesthesia, blood lymph fluid collection, anti-melanization treatment, phenol oxidase inactivation treatment, sediment removal and anaerobic preservation, so as to finally obtain the silkworm blood lymph fluid with inhibited melanization reaction and low endotoxin. The silkworm blood lymph fluid extracted by the prior art contains a large amount of endotoxin, which is extremely harmful to in-vitro cell culture and is one of the bottlenecks for replacing fetal bovine serum with insect blood lymph fluid. The application can reduce the endotoxin concentration in the silkworm lymph fluid. In view of the problems caused by quinone derivatives generated by melanization reaction, the application can reduce the phenol oxidase proenzyme activity in the silkworm blood lymph fluid, long-term inhibit the melanization reaction of the blood lymph fluid, reduce the accumulation of toxic quinones, and make the prepared silkworm blood lymph fluid capable of being used for long-term in-vitro cell culture.

Some non-limiting examples of the disclosure provide a medical device. The medical device can include a tube. The tube can include a wire scaffold coupled to and surrounding a carrier. The wire scaffold can structurally support the carrier. The carrier can include a therapeutic agent. The wire scaffold can be radiopaque and can be biodegradable. When the medical device is positioned in a lymphatic channel of a subject, the wire scaffold can dissolve, exposing the carrier to the lymph fluid of the lymphatic channel to release the therapeutic agent from the carrier. The therapeutic agent can be configured to treat a condition.

The utility model discloses a kind of negative pressure treatment devices, it is related to medical instrument and rehabilitation technical field.The utility model includes negative pressure handle, detachably connected with negative pressure cup body at the bottom of negative pressure handle, and top end is equipped with electrical mixed pipeline, negative pressure cup body bottom circumferential surface is equipped with negative pressure ring, negative pressure ring is equipped with negative pressure mouth between negative pressure cup body bottom surface, negative pressure handle inside is equipped with negative pressure pipeline, negative pressure handle inside is equipped with vibration motor, negative pressure pipeline bottom end is communicated with negative pressure mouth, and another end is connected with electrical mixed pipeline, electrical mixed pipeline is equipped with instrument body away from the one end of negative pressure handle, instrument body is built-in with control unit, and is equipped with solenoid valve, solenoid valve is electrically connected with negative pressure pump.The utility model is lifted to the skin of patient and carries out vibration, for blocked lymphatic fluid to carry out active drainage, and can be aimed at patient's condition Suction adjustment, while to lymphatic fluid blocked passage carries out line dredging, improve dredging treatment effect.

The invention relates to the technical field of estimation, and discloses a reverse transcriptase-polymerase chain reaction combination optimization system for malignant tumor lymphatic invasion judgment. Comprising a data acquisition module used for acquiring different gene data in a tumor gene library, performing systematic clustering analysis on omics statistic indexes in the gene data, and combining a gene expression combination with statistical possibility through a systematic clustering method; the linear elimination module is used for arranging corresponding PCR (Polymerase Chain Reaction) primers on different exons of the gene aiming at the gene expression combination so as to eliminate the colinearity of the gene and mRNA (Messenger Ribonucleic Acid); the integral collaboration module is used for respectively optimizing the reverse transcription reaction and the PCR reaction in the two-step reverse transcriptase polymerase chain reaction to realize integral collaboration of the reverse transcription reaction and the PCR reaction; and the invasion judgment module is used for simultaneously analyzing various genes in the lymph by utilizing the optimized reverse transcriptase polymerase chain reaction so as to judge the lymph invasion condition of the malignant tumor.

The utility model discloses a multi-cavity mechanical flow dividing device for thrombus prevention after a lower limb operation, and belongs to the technical field of thrombus prevention after the lower limb operation. The device comprises a cover body part, a mechanical gas distribution mechanism and a power device. The mechanical gas distribution mechanism is located at the bottom end of the cover body part, the power device is installed below the mechanical gas distribution mechanism, and the power device, the mechanical gas distribution mechanism and the cover body part are tightly connected through the elastic sealing connecting part. And the power device drives the cover body part to rotate, so that the gas inlet of the mechanical gas distribution mechanism is connected with an external gas source, and gas distribution and output are realized. The human body air bags are sequentially inflated with air, circulating pressure is formed from the telecentric end to the proximal end, backflow of venous blood and lymph is promoted, and deep venous thrombosis is prevented. By optimizing the mechanical structure, simplifying the sealing design and increasing the gas flow, the inflation efficiency and the sealing performance are remarkably improved, meanwhile, the production cost is reduced, and the device is suitable for being used in medical institutions and families.

While primary lymphedema is rare, numerous cancer patients develop secondary lymphedema, or the retention of lymphatic fluid. Lymphedema is characterized by progressive, irreversible fibroadipose tissue deposition. Non-surgical approaches such as compression therapy are the most common strategies to address lymphedema but are inadequate in the long term. Surgical procedures can reconstitute lymphatic drainage, but this approach is not curative. A new approach is needed to mitigate fibroadipose tissue deposition in lymphedema.

The presently disclosed subject matter relates to methods and devices for decompressing the lymphatic system. In particular, the present disclosure provides devices for actively or passively decompressing the lymphatic system and methods of their use and deployment within a subject. In certain non-limiting embodiments, a device of the present disclosure can include a pump for actively transferring lymph fluid from the lymphatic fluid into the venous system.

The application discloses a kind of acellular artificial lymph fluid drainage tube and its preparation method and application, the preparation method of acellular artificial lymph fluid drainage tube includes the following steps: with animal blood vessel as raw material, the raw material is treated, washing treatment, enhancement treatment, pore preparation treatment and drying treatment are carried out.This application preparation method is prepared to the acellular artificial lymph fluid drainage tube of preparation, can solve the problem that current lymphatic vessel-venous anastomosis operation is long, operation is difficult, can drain the lymph of patient swelling site to venous system in time after implantation, can quickly relieve swelling symptom.The acellular artificial lymph fluid drainage tube of the application supports the growth, migration, proliferation of autologous cells, and has good biocompatibility, the degradation time can be adjusted to match the reconstruction time of autologous lymphatic return system, to ensure long-term patency.

The application belongs to the technical field of biological medicine, and particularly relates to a VEGFR3 receptor specific binding peptide and application thereof, wherein the amino acid sequence of the VEGFR3 receptor specific binding peptide is shown as SEQ ID NO. 1. The VEGFR3 receptor specific binding peptide can specifically bind with the VEGFR3 receptor on the cell membrane, thereby activating a downstream signal path, stimulating the migration and proliferation of lymphatic endothelial cells, forming a new lymphatic network, and increasing the permeability of the lymphatic vessel, thereby providing convenience for the flow of lymph fluid and further promoting the function of the lymphatic vessel. The VEGFR3 receptor specific binding peptide not only has a significant effect of promoting the proliferation and migration of human lymphatic endothelial cells, but also shows good biocompatibility and biological activity. In addition, the VEGFR3 receptor specific binding peptide can also promote the proliferation and migration of human umbilical vein endothelial cells.