30 results about "Lymph fluid" patented technology

The utility model discloses a breast cancer postoperative affected limb position adjusting device, which belongs to the technical field of medical instruments and comprises a scapular fixing pad and an affected limb adjusting pad, the scapular fixing pad is laid under the back of a patient and connected with the affected limb adjusting pad, and the affected limb adjusting pad can slide relative to the scapular fixing pad to adjust the height of the affected limb adjusting pad. A diseased limb placing cavity is formed in the diseased limb adjusting pad, the width of the diseased limb placing cavity is adjusted according to the height of the diseased limb adjusting pad, when the height of the diseased limb adjusting pad is increased, the width of the diseased limb placing cavity is synchronously increased, and when the height of the diseased limb adjusting pad is reduced, the width of the diseased limb placing cavity is synchronously reduced. The height of the affected limb adjusting pad can be adjusted according to the weight of a patient, meanwhile, the width of the affected limb containing cavity is synchronously adjusted, the hand of the patient is always higher than the elbow, the elbow is higher than the heart, backflow of blood or lymph is facilitated, and the affected limb containing cavity can be used for containing the limbs of the patient all the time.

The invention discloses an electrical stimulation lymphedema rehabilitation device, and relates to the technical field of lymphedema rehabilitation, and the device comprises a housing, and also comprises an electrical stimulation mechanism which is installed at the top of the housing and comprises a plurality of electrode plates; the limb supporting mechanism is installed on the two sides of the shell and comprises a first lantern ring and a second lantern ring; the multi-section massage mechanism is installed in the shell and comprises a plurality of air bags, and one side of each air bag is communicated with an electromagnetic valve; the uniform pressing mechanism is connected with the multi-section massage mechanism and comprises a downward moving anti-sticking mechanism and a translation switching mechanism; the electrical stimulation mechanism further comprises a controller fixed to the top of the shell, and the controller is electrically connected with the multiple electrode slices. By installing the uniform pressing mechanism, uniform massage is achieved, the pressing position of the air bag is changed, the whole limb is pressed uniformly, the pressing strength of all parts of the limb is prevented from being different, the problem that the whole limb is pressed unevenly is effectively solved, and therefore lymph circulation is more efficiently promoted.

The utility model relates to breast nursing technical field especially a breast nursing dredging device, including handle, the surface screw thread connection of handle has the cover cup, the inner chamber of cover cup is provided with the massage head, the inner chamber of cover cup is provided with the adjusting mechanism, the adjusting mechanism includes the massage block, the massage block swing setting is in the inner chamber of cover cup, the surface of massage block is connected with the cannula, the surface of handle is provided with the liquid adding pipe, one end of liquid adding pipe is connected with the connecting pipe, the utility model discloses through the cooperation of massage head, massage block, cannula, liquid adding pipe, connecting pipe, ring pipe, liquid warehouse pipe, driving motor, sliding mouth and ball, is equipped with rolling massage head and sliding mouth, can add the liquid of alleviating automatically in the massage process, utilizes driving motor to drive the ball rolling massage and liquid alleviating combination, can more deeply stimulate breast cell, promotes blood and lymphatic fluid circulation, accelerates the dredging and recovery of breast.

The invention discloses an anastomosis instrument for connecting multiple lymphatic vessels and blood vessels. The anastomosis instrument comprises a blood vessel connecting piece and a plurality of lymphatic connecting tubes. According to the integrated anastomosis instrument, the multiple lymphatic vessels can be connected to the lymphatic connecting tubes respectively through the arrangement of the integrated anastomosis instrument with the multiple lymphatic connecting tubes, and the lymphatic vessels are finally guided into the same vein blood vessel through the through holes; therefore, an efficient connection mode of multiple lymphatic vessels and a single blood vessel is realized, the surgical operation is greatly simplified, the surgical time is shortened, the surgical difficulty is greatly reduced, and the risks of postoperative bleeding, inflammation and vascular stenosis are reduced; in addition, due to the establishment of a plurality of drainage channels, the total drainage efficiency of lymph is effectively improved, and the device is more suitable for clinical conditions with large lymphatic load.

The invention provides a lower limb lymphedema rehabilitation training device which comprises a supporting plate, a first rotating plate is rotatably installed on one side of the supporting plate, a second rotating plate is rotatably installed on the side, away from the supporting plate, of the first rotating plate, and protection assemblies are arranged on the side face of the first rotating plate and the side face of the second rotating plate. A training assembly with adjustable resistance is arranged between the first rotating plate and the supporting plate, and an elastic positioning assembly is arranged between the first rotating plate and the second rotating plate. The lower limb lymphedema rehabilitation training device is used for lower limb training when a patient lies in bed, lymph backflow is assisted by raising legs, rehabilitation treatment of the lower limb lymphedema patient is facilitated, medical staff can adjust the strength of the training device according to the physical quality of the patient in the training process, and the lower limb lymphedema rehabilitation training device is suitable for being used by different staff; meanwhile, the training device can be used for massaging the shanks of the patient, dredging channels and promoting lymph backflow, has ventilation and perspiration functions and is convenient for the patient to use.

A system and method are provided for a body fluid management system for pumping body fluids such as lymph. The body fluid management system may include an implantable pump having: a rotor having a magnetic portion; and inlet and outlet pipes connected to a fluid chamber. The fluid chamber has a volume that can be selectively decreased or increased via the rotor. The rotor is designed to periodically open and close a bend valve at each of the inlet and outlet pipes to allow body fluid to enter the fluid chamber during an inhalation cycle and exit the fluid chamber during an exhalation cycle. The magnetic portion of the rotor can be rotated by an external controller positioned outside the body and near the pump. The external controller may have a magnet magnetically coupled to the rotor to rotate it.

The utility model discloses a novel circumcision anastomat which comprises an inner ring and an outer ring, the inner ring is used for supporting the inner side of a prepuce, the outer ring is composed of a pair of outer ring lock catches which can be mutually locked, a dull knife is arranged on the inner side of each outer ring lock catch, a drainage assembly is arranged on each dull knife, and the outer ring lock catches are buckled on the outer side of the inner ring. The blunt knife extrudes the foreskin tissue on the outer side of the inner ring, the to-be-cut tissue and the reserved tissue are isolated through the arranged inner ring and the locking mechanism, so that the to-be-cut tissue necroses and falls off, then cutting is completed, in addition, tissue fluid is guided out to be away from the isolation belt through the drainage assembly, and it is guaranteed that the position nearby the tissue fluid is kept dry; lymph accumulation and flowing around are avoided, and cross infection is reduced, so that edema is relieved, and healing is faster.

This invention discloses an instrument for connecting lymphatic vessels and blood vessels, comprising a vascular connecting tube, a connecting lumbar tube, and at least one connecting branch tube. The connecting branch tube includes interconnected primary and secondary branches, through which lymph fluid can enter the bloodstream. This instrument enables a stable connection between lymphatic vessels and blood vessels via the instrument itself, rather than relying solely on surgical sutures. This simplifies the surgical procedure, reduces the stringent requirements on the surgeon's skills, significantly reduces the difficulty and risk of the surgery, decreases the incidence of postoperative complications, improves patient recovery speed and treatment effectiveness, and provides a more convenient and reliable connection method, greatly enhancing the convenience, safety, and effectiveness of connecting lymphatic vessels and blood vessels.

This invention relates to a cannulation device and manufacturing method for draining intestinal lymphatic fluid in small animals. The device includes a catheter and a guidewire. The catheter includes an insertion section and a drainage section, the outer and inner diameters of which are smaller than those of the drainage section. The guidewire can be inserted along the catheter, and its outer diameter is smaller than the inner diameter of the insertion section. The insertion tip of the guidewire is blunt and rounded, and the tail end of the guidewire is provided with a handle. By using the cannulation device of this invention, the problems of difficult catheter insertion and significant damage to the mesenteric lymphatic vessels during pretreatment in existing intestinal lymphatic fluid drainage cannulation techniques are solved, reducing the difficulty of surgical operation, shortening the operation time, reducing tissue damage, and improving the success rate of surgery.

1. Name of the product in this design: Medical colorimeter ruler. 2. Purpose of this design: This design is used to compare the colors of patient drainage fluids, secretions, and excretions, such as the color of blood, vomit, stool, sputum, urine, bile, lymph, and various drainage fluids. 3. The key design features of this product are the combination of pattern and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color. 6. Other situations requiring explanation: This design is a two-dimensional product, and the top view, bottom view, left view, and right view are omitted.

The utility model relates to comfortable pressurizing underwear special for breast cancer postoperation, and aims to solve the problems that breast and armpit areas of a patient after breast cancer operation are insufficiently supported, the pressurizing effect is not ideal, infection is prone to occurring, and the comfort degree is poor. The underwear comprises an underwear main body, chest cushion layers, oxter cushion layers, chest and oxter interlayer grooves, chest and oxter pressurizing cushions, adjusting row buckles and the like. The underwear main body is made of a high-elasticity, breathable and skin-friendly fabric, and an antibacterial and anti-infection material is embedded into the underwear main body; the chest and the oxter cushion layer provide necessary support; the design of the interlayer groove and the pressurizing pad realizes personalized pressurizing bandaging; the row buckles are adjusted to adapt to patients with different body types. In addition, the underwear is further provided with the axilla cushion layers which are arranged in a suitable mode, and the requirement for single-side or double-side mammary gland pressurization is met. By means of the comprehensive design, the postoperative comfort of a patient is effectively improved, lymph backflow is promoted, edema is reduced, wound healing is accelerated, the infection risk is reduced, and comprehensive and effective recovery support is provided for the breast cancer postoperative patient.

This invention relates to the field of cognitive data processing technology, and more particularly to a method and system for physical stimulation-driven lymphatic circulation and cognitive enhancement. The system includes a physical stimulation frequency impact assessment module, a stimulation mechanical vibration analysis module, a lymphatic circulation vibration calibration module, and a stimulation frequency drive adjustment module. It utilizes pressure and temperature sensors to monitor the corresponding physical stimulation pressure and the surface temperature of the stimulated skin in real time, performing stimulation frequency impact assessment and stimulation mechanical vibration analysis to generate a physical stimulation mechanical vibration effect. It also acquires lymphatic fluid flow velocity and EEG neural activity signals, performing neurocognitive level analysis and vibration response calibration. Simultaneously, it performs lymphatic circulation cognitive regression analysis and stimulation frequency drive adjustment to generate a physical stimulation frequency drive adjustment scheme corresponding to lymphatic circulation cognitive enhancement. This invention can accurately analyze the correlation between physical stimulation and lymphatic circulation and cognitive enhancement.

The utility model relates to a groin pressurizing device. The groin pressurizing device comprises a pressing sandbag and an auxiliary sandbag connected with the pressing sandbag, the auxiliary sandbag is connected with the compression sandbag through a connecting belt, and a fixing assembly used for fixing the connecting belt is arranged on the compression sandbag; the whole pressing sandbag is of a structure with the front pointed and the rear wide, and the width and the thickness of the pressing sandbag from the front end to the rear end are in a gradually-increasing trend. And the compression sandbag is detachably connected with the self-adhesion fuzzing cloth. Compared with the prior art, the groin pressurizing device has the advantages that effective sandbag fixing of a groin postoperative patient can be achieved, a better pressurizing recovery effect is achieved, bleeding, exudation and edema can be reduced, lymph backflow is promoted, and the risk of postoperative complications is reduced.

The application belongs to the technical field of biology, and discloses a system for continuous drainage of mesenteric lymph fluid and application thereof, which comprises a mesenteric lymph vessel catheter for being inserted into a mesenteric lymph vessel to drain mesenteric lymph fluid, a jugular vein catheter for being inserted into a jugular vein, a collector for collecting lymph fluid, and a conscious activity device comprising a quick connection button VAB and a mesenteric lymph fluid collecting tube, wherein the outlet end of the mesenteric lymph fluid collecting tube is in the same height as the inlet end of the mesenteric lymph vessel catheter. The method can realize real-time and long-term collection of lymph fluid under the conditions of free activity, unrestricted diet and water and normal physiological state of rats, can avoid the influence of surgical stress, general anesthesia or animal restriction on experimental results, can reflect the real state of lymph fluid, and can be applied to the fields of research on lymph vessel absorption capacity and functional state and explanation of disease mechanism.

The utility model provides an otolithiasis semicircular canal three-dimensional model, which relates to the technical field of medical models, and comprises a base, a pillar is fixedly connected above the base, the end part of the pillar is rotatably connected with a model arc frame, and the inside of the model arc frame is rotatably connected with a simulation head model through a fulcrum shaft. The simulation semicircular canal model is fixed outside the simulation head model in a popular and easy-to-understand manner, so that the inclination angle of the simulation semicircular canal model is consistent with the inclination angle of the semicircular canal in a human body, understanding of a patient is facilitated, and the simulation semicircular canal model is filled with a glycerin solution for simulating internal lymph in the semicircular canal, so that the simulation head model can be used for simulating the internal lymph in the semicircular canal. Along with the inclination and rotation of the simulation head model, the movement track and path of the otolith crystal model in the simulation semicircular canal model in the internal lymph can be observed, and the problem that a patient cannot clearly understand the treatment process of otolithiasis due to the fact that the patient cannot easily understand the structure of the patient and the relation between the angle of the canal body model and the angle of the head of the human body is solved.

The application discloses a preparation method of silkworm blood lymph fluid with inhibited melanization reaction and low endotoxin, which comprises the following steps: low endotoxin silkworm variety selection, silkworm body disinfection and impurity removal, silkworm body low-temperature anesthesia, blood lymph fluid collection, anti-melanization treatment, phenol oxidase inactivation treatment, sediment removal and anaerobic preservation, so as to finally obtain the silkworm blood lymph fluid with inhibited melanization reaction and low endotoxin. The silkworm blood lymph fluid extracted by the prior art contains a large amount of endotoxin, which is extremely harmful to in-vitro cell culture and is one of the bottlenecks for replacing fetal bovine serum with insect blood lymph fluid. The application can reduce the endotoxin concentration in the silkworm lymph fluid. In view of the problems caused by quinone derivatives generated by melanization reaction, the application can reduce the phenol oxidase proenzyme activity in the silkworm blood lymph fluid, long-term inhibit the melanization reaction of the blood lymph fluid, reduce the accumulation of toxic quinones, and make the prepared silkworm blood lymph fluid capable of being used for long-term in-vitro cell culture.

Some non-limiting examples of the disclosure provide a medical device. The medical device can include a tube. The tube can include a wire scaffold coupled to and surrounding a carrier. The wire scaffold can structurally support the carrier. The carrier can include a therapeutic agent. The wire scaffold can be radiopaque and can be biodegradable. When the medical device is positioned in a lymphatic channel of a subject, the wire scaffold can dissolve, exposing the carrier to the lymph fluid of the lymphatic channel to release the therapeutic agent from the carrier. The therapeutic agent can be configured to treat a condition.

The utility model discloses a kind of negative pressure treatment devices, it is related to medical instrument and rehabilitation technical field.The utility model includes negative pressure handle, detachably connected with negative pressure cup body at the bottom of negative pressure handle, and top end is equipped with electrical mixed pipeline, negative pressure cup body bottom circumferential surface is equipped with negative pressure ring, negative pressure ring is equipped with negative pressure mouth between negative pressure cup body bottom surface, negative pressure handle inside is equipped with negative pressure pipeline, negative pressure handle inside is equipped with vibration motor, negative pressure pipeline bottom end is communicated with negative pressure mouth, and another end is connected with electrical mixed pipeline, electrical mixed pipeline is equipped with instrument body away from the one end of negative pressure handle, instrument body is built-in with control unit, and is equipped with solenoid valve, solenoid valve is electrically connected with negative pressure pump.The utility model is lifted to the skin of patient and carries out vibration, for blocked lymphatic fluid to carry out active drainage, and can be aimed at patient's condition Suction adjustment, while to lymphatic fluid blocked passage carries out line dredging, improve dredging treatment effect.

The invention relates to the technical field of estimation, and discloses a reverse transcriptase-polymerase chain reaction combination optimization system for malignant tumor lymphatic invasion judgment. Comprising a data acquisition module used for acquiring different gene data in a tumor gene library, performing systematic clustering analysis on omics statistic indexes in the gene data, and combining a gene expression combination with statistical possibility through a systematic clustering method; the linear elimination module is used for arranging corresponding PCR (Polymerase Chain Reaction) primers on different exons of the gene aiming at the gene expression combination so as to eliminate the colinearity of the gene and mRNA (Messenger Ribonucleic Acid); the integral collaboration module is used for respectively optimizing the reverse transcription reaction and the PCR reaction in the two-step reverse transcriptase polymerase chain reaction to realize integral collaboration of the reverse transcription reaction and the PCR reaction; and the invasion judgment module is used for simultaneously analyzing various genes in the lymph by utilizing the optimized reverse transcriptase polymerase chain reaction so as to judge the lymph invasion condition of the malignant tumor.

The utility model discloses a multi-cavity mechanical flow dividing device for thrombus prevention after a lower limb operation, and belongs to the technical field of thrombus prevention after the lower limb operation. The device comprises a cover body part, a mechanical gas distribution mechanism and a power device. The mechanical gas distribution mechanism is located at the bottom end of the cover body part, the power device is installed below the mechanical gas distribution mechanism, and the power device, the mechanical gas distribution mechanism and the cover body part are tightly connected through the elastic sealing connecting part. And the power device drives the cover body part to rotate, so that the gas inlet of the mechanical gas distribution mechanism is connected with an external gas source, and gas distribution and output are realized. The human body air bags are sequentially inflated with air, circulating pressure is formed from the telecentric end to the proximal end, backflow of venous blood and lymph is promoted, and deep venous thrombosis is prevented. By optimizing the mechanical structure, simplifying the sealing design and increasing the gas flow, the inflation efficiency and the sealing performance are remarkably improved, meanwhile, the production cost is reduced, and the device is suitable for being used in medical institutions and families.

The presently disclosed subject matter relates to methods and devices for decompressing the lymphatic system. In particular, the present disclosure provides devices for actively or passively decompressing the lymphatic system and methods of their use and deployment within a subject. In certain non-limiting embodiments, a device of the present disclosure can include a pump for actively transferring lymph fluid from the lymphatic fluid into the venous system.

The application discloses a kind of acellular artificial lymph fluid drainage tube and its preparation method and application, the preparation method of acellular artificial lymph fluid drainage tube includes the following steps: with animal blood vessel as raw material, the raw material is treated, washing treatment, enhancement treatment, pore preparation treatment and drying treatment are carried out.This application preparation method is prepared to the acellular artificial lymph fluid drainage tube of preparation, can solve the problem that current lymphatic vessel-venous anastomosis operation is long, operation is difficult, can drain the lymph of patient swelling site to venous system in time after implantation, can quickly relieve swelling symptom.The acellular artificial lymph fluid drainage tube of the application supports the growth, migration, proliferation of autologous cells, and has good biocompatibility, the degradation time can be adjusted to match the reconstruction time of autologous lymphatic return system, to ensure long-term patency.

The application belongs to the technical field of biological medicine, and particularly relates to a VEGFR3 receptor specific binding peptide and application thereof, wherein the amino acid sequence of the VEGFR3 receptor specific binding peptide is shown as SEQ ID NO. 1. The VEGFR3 receptor specific binding peptide can specifically bind with the VEGFR3 receptor on the cell membrane, thereby activating a downstream signal path, stimulating the migration and proliferation of lymphatic endothelial cells, forming a new lymphatic network, and increasing the permeability of the lymphatic vessel, thereby providing convenience for the flow of lymph fluid and further promoting the function of the lymphatic vessel. The VEGFR3 receptor specific binding peptide not only has a significant effect of promoting the proliferation and migration of human lymphatic endothelial cells, but also shows good biocompatibility and biological activity. In addition, the VEGFR3 receptor specific binding peptide can also promote the proliferation and migration of human umbilical vein endothelial cells.

Disclosed herein is a method of treating neurodegenerative diseases involving accumulation of abnormal proteins in the central nervous system (CNS) of a user. The method includes utilizing an intraoral device to apply photobiomodulation and vibration to specific points on hard and soft palates of the user to stimulate the user's glymphatic system and decongest hyperphosphorylated tau and amyloid proteins and toxins, and simultaneously with the utilization of the intraoral device, applying a transcranial device to exert vasopneumatic compression and photobiomodulation on the user's head and neck to stimulate the user's lymphatic system and enhance the flow of lymphatic fluid towards the subclavian lymphatic pathway.

An implantable lymph node replacement construct (10) comprising a body (12) having a plurality of inlets (24,26) and a lesser number of outlets (30). The body (12) further having an internal structure defining a fluid communication path through the body (12) from the inlets (24,26) to the outlet or outlets (30). The internal structure of the body (12) comprises an inlet portion (38), a convergent portion (40) and an outlet portion (42) such that lymph received by the construct (10) at the inlets (24,26) is conveyed through the inlet portion (38) of the internal structure to the convergent portion (40) whereupon the lymph is combined before passing to the outlet or outlets (30).

The invention discloses a shellfish hemolymph living body collection method which comprises the following steps: marking a puncture site which is a tail end point of a shellfish hinge part; marking a puncture auxiliary line, wherein the puncture auxiliary line is a straight line which passes through the puncture site and is tangent to the hinge part of the shellfish; the tip of the blood drawing needle head is placed at the puncture site, the straight line where the blood drawing needle head is located is collinear with the puncture auxiliary line, the blood drawing needle head is rotated anticlockwise with the tip of the blood drawing needle head as the circle center, the rotation angle is the puncture angle, the puncture angle is 22-45 degrees, and the puncture direction of the blood drawing needle head entering the shellfish is fixed; a blood drawing needle head enters the shellfish from the puncture site in the puncture direction; and after the tip of the blood drawing needle head reaches the position of the posterior adductor muscle of the shellfish, the shellfish hemolymph is drawn. The method has no damage, and the quality and the maximum extraction amount of extracted hemolymph liquid are obviously higher than those of a traditional shell breaking method.

Devices and methods of the disclosure use an intravascular catheter with deployable sealing elements to create a fluid trap around an outlet of a lymphatic duct and drain lymph passively to a collection vessel that may be pressurized to a predetermined pressure or a partial vacuum. Due to the fixed pressure, the device creates a low-pressure area at the lymphatic duct, which drains lymph passively without any mechanical pump or impeller. In certain aspects, a device includes a catheter for insertion into a vein of the venous angle of a patient, with proximal and distal sealing elements deployable to seal the vein to thereby define a fluid trap around the lymphatic outlet. A port within the fluid trap opens to a drainage lumen extending along the catheter to a collection vessel. The device may be configured such that the drainage lumen passively drains the fluid trap into the collection vessel.

This disclosure relates to improving the outflow of glymph / lymphophilic solutes from the central nervous system.

The invention discloses a construction method of a viral deafness mouse model, and relates to an animal model construction technology, the method comprises the following steps: (1) narcotizing a mouse, cutting the skin after ears, separating subcutaneous tissues, and exposing the stethoblister of the mouse; (2) preparing an opening in the stethoscope bubble to expose a cochlea round window; (3) puncturing and injecting a solution containing viruses into the cochlear lymph through the round window membrane of the round window; (4) sealing the operation area; according to the method, a round window membrane local micro-injection technology is adopted, the blood-lost barrier is effectively broken through, the technical problems that a traditional systemic infection model is high in death rate and unstable in model forming are solved, the model constructed through the method has the remarkable advantages of being high in survival rate, high in model forming rate and stable in phenotype, the pathological characteristics of human viral deafness are accurately simulated, and the method is suitable for large-scale popularization and application. And a standardized ideal experimental platform is provided for deafness-causing mechanism research and drug screening.

The utility model discloses an upper limb lymphedema limb lifting maintaining garment which comprises a jacket body, a first buckling piece and a second buckling piece, an affected limb side cuff and a healthy limb side cuff are sewn to the two sides of the jacket body respectively, sleeves are sewn to the affected limb side cuff, and connecting pieces extending to cover the corresponding palms of the human body are arranged at the cuff positions of the sleeves. The first buckling piece is arranged on the connecting piece, and the second buckling piece is arranged on the side, close to the healthy limb side cuffs, of the coat body. An inner pocket with two open sides is arranged on the front side of the jacket body. According to the limb lifting clothes, the connecting pieces covering the palms are arranged at the cuffs of the sleeves on the side of the affected limbs, and the first buckling pieces and the second buckling pieces are detachably buckled, so that after a patient wears the limb lifting clothes, the affected limbs are fixed to the chest and shoulder positions on the healthy side, the fingers at the far ends of the affected limbs are located at the high positions, and the arms form a step shape; and blood and lymph fluid can easily flow to a low position from a high position under the action of gravity, so that swelling improvement is facilitated.