Traditional Chinese medicine composition for warming and tonifying kidney-yang and anti-depression and its preparation method and use
A technology for warming and tonifying kidney-yang and composition, which is applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of unstable curative effect, etc. Effect
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Embodiment 1
[0030] Example 1 Toxicity Comparison of Different Compatible Prescriptions of Curculigo and Epimedium and Correlation between Toxicity and Content
[0031] Curculigo is a special medicine for warming the kidney and tonifying yang. Epimedium can also benefit the essence, qi and tonify the kidney and yang. The two medicines are compatible and must be used for each other. They complement each other. Ancient and modern records of the nature and flavor of curculigo are pungent or sweet, warm or hot, and poisonous. Theoretically speaking, the combination of "two immortals" may produce synergistic effect and detoxification, but whether it can indeed synergize and detoxify, and the compatibility ratio of synergistic effect and detoxification, the correlation with the content of ingredients, and the pharmacological mechanism need to be clarified. The following research focuses on the determination and comparison of the toxicity of Erxianyao to the water extracts and ethanol extracts of...
Embodiment 2
[0064] Example 2 Comparative study on the effect of supplementing kidney yang with different compatible prescriptions of Curculigo and Epimedium and the original prescription of Erxian Decoction
[0065] Erxian Decoction is a traditional Chinese medicine compound created by the famous doctor Zhang Berna in the 1950s. Erxian Decoction warms and invigorates kidney yang, nourishes blood and replenishes qi, and is mainly used for menopausal syndrome. Chinese medicine believes that menopausal syndrome is mainly caused by kidney deficiency, and Curculigo-Epimedium is the two king herbs in "Erxian Decoction". For the effect of qi and kidney yang, traditional Chinese medicine often combines the two with 1׃1. Our previous studies have shown that the combination of the two can reduce the poison of curculigo, but whether it can enhance the effect of tonifying kidney yang and the best combination of synergistic and attenuating toxicity remains to be further explored. In this experiment,...
Embodiment 3
[0153] Example 3 Comparison of Antidepressant Effects of Curculigo and Epimedium Huo with Different Compatibility Prescriptions and Erxian Decoction
[0154] Depression refers to psychological disorders caused by various reasons. It is a common and frequently-occurring disease that seriously endangers human physical and mental health. Currently, there is a lack of highly effective and low-toxic drugs for the treatment of depression. Curculigo curculigo and Epimedium (also known as Xianlingpi) are a well-known Chinese medicine pair called "Erxian", and they are also the two main ingredients in "Erxian Decoction" in traditional Chinese medicine. Studies have shown that Curculigo curculigo has antidepressant effect; its antidepressant material basis is phenolic components such as curculin and orcinol glucoside; the same Epimedium extract also has certain antidepressant effect, and its antidepressant effect is similar to that of Nerve cell protection. However, there is no relevan...
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